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Published by Mario Gietl & Max Griessinger
Beyond Lifespan is a longevity and biohacking podcast hosted by Mario Gietl and Max Griessinger. Join us on our journey to extend healthspan — not just lifespan. As medical doctors we live and breathe longevity 24/7: developing supplements, testing the latest health gadgets and wearables, and diving deep into the science of healthy aging. Every episode brings you evidence-based insights on longevity, biohacking, nutrition, and anti-aging — straight from the source. Whether you want to optimize your health, understand the science behind anti-aging, or discover what actually works, you'll get it all firsthand. Disclosure: This is an AI-translated English version of the original German podcast, using synthetic versions of the hosts’ voices with their consent.
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Bloating isn't always caused by excess gas or a food intolerance. Mario and Max explore how constipation, gut sensitivity, diaphragm coordination, stress and the menstrual cycle can contribute. They discuss food triggers, fiber, the limits of probiotics and digestive enzymes, and why a 10–15-minute walk after eating is worth building into your routine.
Protein quality matters—but how do whey, plant-based blends and collagen compare for muscle maintenance? Mario and Max explain essential amino acids, digestibility and leucine, challenge the supposed 30-gram-per-meal limit, and discuss what to check on supplement labels. They also tackle protein needs after menopause and share a practical way to make breakfast more protein-rich.
Five popular diets take very different approaches to healthy eating—but how do they compare for longevity? Mario and Max discuss Mediterranean, ketogenic, vegan, Paleo and carnivore diets, weighing the evidence, nutritional trade-offs and everyday practicality. They explain why processing levels matter, answer whether vegetarians can build muscle, and share a simple whole-food meal strategy built around protein and fiber.
Oral health and its possible connections to chronic inflammation take center stage as Mario and Max speak with biological dentist Dr. Fabian Schick. They explore fluoride and hydroxyapatite, the oral microbiome, amalgam fillings, wisdom tooth healing, root canal-treated teeth and ceramic implants. Schick explains his approach to individualized diagnostics and shares his daily oral-care routine, while acknowledging controversy around jawbone cavitations and the limits of individual case reports.
In this Community Hotline episode, Mario and Max answer your questions about blood tests, supplements, and sports nutrition. They explain why maltodextrin can be easier on the stomach during endurance exercise, discuss the infection risks associated with raw milk, and put elevated homocysteine levels into medical context.
In her early thirties, a multiple sclerosis diagnosis suddenly changed sports journalist Anna Kraft’s life. Mario and Max speak with her about how she manages chronic fatigue through a radical dietary change, targeted pacing, and comprehensive blood testing. The two physicians also assess the risks of vitamin overdoses and explain the three fundamental pillars of healthy longevity.
Breathe through your nose instead of your mouth? Mario and Max explain how nasal breathing more than doubles the release of nitric oxide, thereby noticeably increasing oxygen saturation in the body. They also explore how nasal strips, mouth taping, and nasal rinses can help with blocked airways.
Take a warm shower in the evening to cool down and fall asleep faster? Mario and Max explain the physiological process behind vasodilation and how a controlled drop in core body temperature can improve sleep efficiency. They also reveal why timing is crucial—and why just ten minutes in the sauna can be enough.
Acute stress cannot be switched off through willpower alone—but it can be regulated through breathing. Mario and Max explain the neurobiological effects of the physiological sigh, also known as cyclic sighing. They show how a double inhale reopens collapsed alveoli and how a slow exhale activates the vagus nerve.
Should you drink coffee immediately after waking up or wait 90 minutes? Mario and Max examine the widespread biohacking myth surrounding cortisol stacking and the typical afternoon slump. They explain why the timing of your last coffee is usually far more important for sleep quality than your first espresso of the day.
If you struggle to get out of bed in the morning, a lack of natural light indoors may be the reason. In this biohack, Mario and Max explain how daylight can increase morning cortisol levels by up to 40%—and why regular bathroom lighting simply isn’t enough.
Cold showers in the morning for better focus and fat burning? Mario and Max debunk myths about brown adipose tissue, explain how cold actually affects the nervous system, show how box breathing helps during ice baths, and explain why people who take cold showers get sick less often.
Constantly distracted, yet able to spend hours on something you love—is it ADHD? Medical Doctors Mario Gietl and Max Griessinger explore adult ADHD, dopamine, hyperfocus and late diagnosis. Plus: treatment approaches, a listener’s question about being diagnosed at 41, and this episode’s biohack on sleep timing.
Even one alcoholic drink can disrupt sleep, increase next-day stress and cause cellular damage. We explain why there is no risk-free level of alcohol consumption—and why drinking can still feel relaxing at first.
Up to 45% of dementia cases may be preventable or delayable through modifiable risk factors. We cover blood pressure, blood sugar, sleep, exercise, hearing loss, diet, social connection and lifelong learning—and the steps you can take now.
Taking magnesium or melatonin but still sleeping poorly? The problem is often not the supplement—it is light, caffeine, alcohol, late meals, temperature and stress. Learn why your circadian rhythm matters more than another sleep pill.
B vitamins are often considered harmless, yet deficiencies can have serious consequences and excessive vitamin B6 may cause nerve damage. We explain all eight B vitamins, common deficiencies, lab markers, risk groups and how to choose a B-complex.
Magnesium oxide, citrate, bisglycinate, malate, taurate or L-threonate—which form should you choose? We compare absorption, tolerance and uses, and explain how to read the elemental magnesium amount on the label.
Insulin resistance can develop years before fasting glucose or HbA1c becomes abnormal. We explain fasting insulin, HOMA-IR, early warning signs, testing pitfalls and the lifestyle strategies that can improve insulin sensitivity.
Collagen is marketed for skin, joints, tendons and connective tissue, but how strong is the evidence? We review benefits, limitations, risks and the differences between hydrolyzed collagen peptides, gelatin and vegan products.
Ranking source
Apple Podcasts rankings via the Mato Topic Intelligence Platform.
Observed November 4, 2026.
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