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Published by Sanjay Bhojraj MD
Rethinking heart health, one question at a time. I’m Dr. Sanjay Bhojraj—interventional cardiologist, functional medicine expert, and lifelong student of what really keeps us well. In this podcast, we go beyond prescriptions and procedures to explore the deeper drivers of health, disease, and healing. From inflammation to intuition, cholesterol to consciousness, I sit down with doctors, researchers, and changemakers who are reshaping how we think about the heart—and the whole human behind it. Whether you're a fellow clinician, a health seeker, or someone navigating your own transformation, this show will challenge what you thought you knew—and invite you to stay curious.
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High blood pressure is one of the most common cardiovascular problems in the world—but what if the number on the blood pressure cuff is only part of the story? In this episode of The Curious Cardiologist , Dr. Sanjay Bhojraj sits down with Mark Young, a functional medicine practitioner, entrepreneur, and CEO of Zona Health, to explore a different way of thinking about cardiovascular wellness. Mark shares his journey from academia and health marketing into functional medicine and explains why he became interested in the relationship between endothelial function, circulation, nitric oxide, and blood pressure. The conversation dives into the concept of isometric exercise —static muscle contractions such as planks, wall sits, and grip exercises—and how Zona Health has developed a guided hand-grip device around this type of exercise. Dr. Sanjay and Mark also discuss the importance of lifestyle interventions, patient ownership, cardiovascular conditioning, medication conversations, and the challenge of separating evidence-based health information from online wellness noise. The episode ultimately asks listeners to remain curious, question assumptions, and understand cardiovascular health as a system rather than simply a number on a blood pressure monitor. The conversation explores: Why blood pressure may be viewed as part of a larger cardiovascular picture What the endothelium is and why it matters The relationship between vascular function and blood pressure How nitric oxide contributes to vasodilation What isometric exercise actually does How grip-based isometric training works Why Zona Health developed a guided isometric device Cardiovascular conditioning and lifestyle interventions The importance of patient education and health ownership How to evaluate health information online Why Mark believes people need to remain curious rather than blindly accepting health claims TIMESTAMPS 00:00 — Meet Mark Young: Functional Medicine & Cardiovascular Health 07:37 — Taking Ownership of Your Health 14:30 — The Problem With Treating High Blood Pressure as Just a Number 19:00 — “Question Everything”: Rethinking the Standard of Care 25:09 — What Is the Endothelium? 29:50 — What Is Isometric Exercise? 32:41 — How the Zona Hand-Grip Device Works 40:54 — Sanjay Tests the Zona Device Live 43:02 — What Does the Research Say About Zona? 53:10 — Why a 12-Minute Lifestyle Change Can Feel So Difficult Connect with Mark Young: 🌐 Website: themarkyoung.com 📸 Instagram: @themarkyoung 💼 LinkedIn: Mark Young Learn more about Zona Health: 🌐 zona.com 📸 @zonahealth
What if hormone health is about far more than fertility and menopause symptoms? In this episode of The Curious Cardiologist , Dr. Sanjay Bhojraj sits down with double-boarded OB-GYN and integrative medicine physician Dr. Jennifer Roelands to explore the connection between hormones, metabolism, fertility, cardiovascular health and longevity. Dr. Jen shares her own experience discovering PCOS and thyroid disease after struggling to conceive her second child—and how being told she couldn't have PCOS because she was “skinny” ultimately changed the direction of her medical career. The conversation explores why PCOS should be viewed as more than a gynecological condition, why menstrual cycles can provide important clues about overall health, and how insulin resistance, inflammation and thyroid health fit into the picture. They then dive into perimenopause and menopause, including estrogen, progesterone and testosterone, and discuss hormone replacement therapy, healthspan, bone health, muscle, cardiovascular health and brain health. The conversation also covers testosterone and men's health, environmental endocrine disruptors, fertility, lifestyle, nutrition and why earlier intervention may matter when it comes to chronic disease prevention. In this episode, they explore: • Why PCOS is more than a gynecological condition • The connection between PCOS and metabolic health • Why menstrual cycles may provide important health information • Insulin resistance and inflammation • Fertility and mitochondrial health • Why women's health can be missed in conventional medicine • What happens during perimenopause • Estrogen, progesterone and testosterone • Symptoms associated with hormonal changes • Hormone replacement therapy and healthspan • Early menopause and long-term health considerations • Testosterone and men's health • TRT, fertility and endogenous testosterone production • Lifestyle factors that influence testosterone • Endocrine-disrupting chemicals • Consumer products and environmental exposures • Why prevention should begin earlier in life Dr. Jen also shares practical ways patients can become more informed about environmental exposures, including resources such as the Environmental Working Group's Skin Deep database. Where to find Dr. Jen: Pivot Book : https://drjenniferroelands.com/pivotbook/ Drs Guide : https://drjenniferroelands.com/guide/ YouTube Channe l: https://youtube.com/@drjenniferroelandsmd Website : https://drjenniferroelands.com/ Timestamps 00:00 — Introduction: Hormones and the Missing Piece of Women's Health 02:20 — Why Dr. Jen Left Conventional Medicine 02:48 — Her Personal PCOS and Fertility Story 04:08 — Discovering PCOS and Thyroid Disease 05:08 — “My Labs Look Normal, But I Don't Feel Normal” 06:30 — Treating PCOS Beyond Medication 08:26 — Why PCOS Is a Metabolic Problem 09:52 — Should Your Period Be a Vital Sign? 10:54 — Fertility, Mitochondria and Long-Term Health 12:47 — What Conventional Medicine Gets Wrong About Lifestyle 16:07 — Why PCOS Research Is Still Limited 16:39 — The Underfunding of Women's Health Research 17:35 — Birth Control vs. Hormone Replacement 18:29 — PCOS Meets Perimenopause 20:07 — Why Prevention Should Start Earlier 21:17 — Risk Stratifying Women for Long-Term Health 22:38 — Genetics, Epigenetics and PCOS 23:53 — Pregnancy as a Window Into Future Health 25:10 — Why OB-GYNs Often Become Primary Care 26:45 — What Does Longevity Medicine Really Mean? 27:36 — Menopause as Healthspan Therapy 28:17 — When Does Perimenopause Actually Start? 29:35 — The Symptoms of Perimenopause 31:10 — Palpitations, Progesterone and Hormonal Changes 32:25 — Estrogen, Memory, Skin, Bladder and More 33:14 — Why Testosterone Is the Undervalued Hormone 34:21 — Early Menopause and Cardiovascular Risk 35:26 — The Legacy of the Women's Health Initiative 36:29 — When Should Women Consider HRT? 37:33 — Why Timing May Matter 39:25 — Andropause and Testosterone in Men 40:29 — Insulin, SHBG and Testosterone 42:12 — Who Actually Needs Testosterone Therapy? 44:18 — Why HRT and TRT Can't Replace Lifestyle 45:30 — Testosterone, Fertility and Endogenous Production 46:44 — The Amazon Analogy for Free Testosterone 47:11 — Testosterone and Cardiovascular Health 48:41 — Testosterone Therapy in Younger Men 50:03 — Medical Optimization vs. Bodybuilding 50:32 — Testosterone Risks and Side Effects 51:30 — Endocrine Disruptors Are Everywhere 52:30 — Reducing Everyday Toxin Exposure 53:54 — Why “Natural” Doesn't Always Mean Safe 55:06 — Teaching the Next Generation to Be Savvy Consumers 55:59 — Menstrual Products and Environmental Exposures 56:53 — Endocrine Disruptors and Pregnancy 58:28 — Finding Hope in Prevention 59:34 — “Eat More Plants, Not What's Made in a Plant” 59:49 — Rapid Fire: Dr. Jen's Favorite Things
What if the heart could do more than pump blood? In this episode of The Curious Cardiologist , Dr. Sanjay Bhojraj sits down with entrepreneur, author and heart-centered leadership expert Mindie Kniss to explore the fascinating intersection of heart intelligence, heart coherence, intuition, spirituality, leadership and personal transformation . Mindie shares the remarkable story behind her work—from leaving a successful pharmaceutical career and moving into entrepreneurship, to experiencing bankruptcy, foreclosure and $100,000 of credit-card debt, and ultimately rebuilding her life and business. She also opens up about the devastating loss of her husband and how the practices she had spent years teaching helped her navigate grief and find a path forward. The conversation explores why we often live from the “head” instead of the heart, how stress can affect our ability to communicate clearly within ourselves, why gratitude may be more powerful when it is physically felt rather than simply thought, and how heart coherence can influence the people around us. They also discuss authentic leadership, radical ownership, intuition, purpose, Ikigai , and the importance of trusting yourself when life doesn't go according to plan. In this episode, you'll discover: • What “heart intelligence” means • Why the heart isn't simply a pump • The relationship between the heart and brain • What heart coherence is • How stress can affect internal communication • Why intuition may be more than pattern recognition • How gratitude can become a physiological experience • The difference between thinking gratitude and actually feeling it • How presence can help interrupt anxiety and overthinking • Why authentic leaders create stronger connections • What radical ownership looks like • How adversity can become part of your development • How Ikigai can help clarify purpose • Why trusting yourself is essential to meaningful leadership Mindie also discusses her books Heart of Consciousness and The Collective Heart , her Heart Path work, and her upcoming Heart Path book scheduled for publication through Hay House in March 2027. Timestamps 00:00 — Introduction: What Does It Mean to Lead With Your Heart? 00:58 — Meet Mindie Kniss 03:16 — From Traditional Career to Entrepreneurship 05:27 — The Golden Handcuffs of Corporate Success 06:55 — The “Slow Suicide to My Soul” 07:24 — A Life-Changing Fellowship in Kenya 10:53 — When the Universe Opened a Door 13:02 — The Entrepreneurial Crash 14:45 — $100,000 in Debt, Foreclosure and Rock Bottom 16:10 — Meeting Her Future Husband 18:08 — Rebuilding Her Business and Money Mindset 19:40 — The Tragedy That Changed Everything 20:05 — Grief, the Heart and Finding a Path Forward 21:50 — What Is Neurocardiology? 23:33 — Sedona, Nature and the Birth of Heart Path 25:57 — Why Personal Experience Makes a Better Coach 26:43 — Finding the Lesson in Your Worst Experiences 29:59 — The Science Behind Heart Intelligence 31:53 — The Heart-Brain Connection and Coherence 34:01 — Can One Person's Coherence Affect Another? 36:22 — Heart Coherence in Real Life 37:34 — How Calm People Change a Room 40:24 — The First Heart Key: Gratitude 42:14 — Why Thinking Gratitude Isn't Enough 44:04 — The Story of the Gifted Duck 45:59 — Emotional Resilience as a Muscle 49:41 — Moving Beyond the “Woo-Woo” 50:11 — Anxiety, Depression and Getting Out of Your Head 51:09 — The Fascinating Question of Heart Cancer 52:48 — Trust, Authenticity and Leadership 55:54 — Radical Ownership 57:10 — Why the Present Moment Matters 59:05 — The Only Way Through Is Through 1:00:18 — What Is Ikigai? 1:01:12 — Purpose, Dharma and Trust 1:01:44 — Mindie's Upcoming Hay House Book 1:02:12 — Rapid Fire: Favorite Place, Food and Curiosity 1:04:04 — Mindie's Books and Where to Find Her 1:05:21 — Final Thoughts: The Heart Is More Than a Muscle
Is fatigue, brain fog, weight gain, declining muscle, and loss of motivation simply part of getting older—or are your hormones trying to tell you something? In this episode of The Curious Cardiologist , Dr. Sanjay Bhojraj sits down with functional medicine expert Joya Van Der Laan to discuss the science of testosterone, estrogen, menopause, metabolic health, and longevity. They explore why hormone levels are changing across modern populations, the difference between "normal" and "optimal" lab values, and why muscle may be one of the strongest predictors of healthy aging. The conversation also covers bioidentical hormone replacement therapy, sleep, nutrition, strength training, cardiovascular health, and how functional medicine approaches root causes rather than simply treating symptoms. Whether you're navigating menopause, low testosterone, or simply looking to improve your health-span, this episode provides practical, evidence-informed insights to help you feel stronger, think clearer, and age with greater vitality. In this episode you'll learn: Why testosterone levels have declined over recent decades The difference between "normal" and "optimal" hormone levels Menopause, perimenopause, and andropause Strength training as the #1 longevity strategy Hormones and cardiovascular health Functional medicine vs conventional medicine Sleep apnea, snoring, and hormone health Bioidentical hormone replacement therapy (BHRT) Pellets vs creams vs injections Practical lifestyle strategies to optimize hormones naturally Timestamps 00:00 Introduction 01:45 Joya's Journey into Functional Medicine 04:15 Why Root-Cause Medicine Matters 05:30 Understanding Low Testosterone 08:00 Symptoms Most Men Ignore 10:30 Natural Ways to Support Testosterone 15:00 Free vs Total Testosterone 17:00 Exercise, Muscle & Longevity 22:00 "Normal" vs "Optimal" Hormone Levels 24:00 Testosterone & Metabolic Health 26:30 Sleep, Snoring & Hormones 30:00 Testosterone Therapy Options 33:00 Pellets vs Creams vs Injections 35:30 Women's Hormones & Menopause 39:00 Hormone Testing & Functional Medicine Labs 43:00 Hormones After Cancer: What Does the Evidence Say? 49:00 The Future of Functional Medicine 53:00 Final Takeaways
South Asians develop heart disease, diabetes, and metabolic dysfunction at dramatically higher rates than almost any other population—but why? In this episode, Dr. Sanjay Bhojraj is joined by functional medicine practitioner Shefaly Ravula to unpack the unique biology behind South Asian metabolic health. Together they explore the "thrifty gene" hypothesis, insulin resistance, muscle loss, continuous glucose monitoring (CGMs), gut health, personalized nutrition, cholesterol testing, and why traditional risk factors often miss the bigger picture. They also discuss practical strategies for improving metabolic health, including building muscle, optimizing protein intake, improving blood sugar regulation, interpreting advanced lipid testing, and adapting traditional Indian foods without abandoning cultural identity. Whether you're South Asian or simply interested in longevity, prevention, and precision medicine, this conversation offers actionable insights into one of today's biggest health challenges. Together they discuss: Why South Asians have unique metabolic risks The truth about insulin resistance Continuous Glucose Monitors (CGMs) Muscle, longevity, and blood sugar Advanced cholesterol testing Functional medicine vs conventional medicine Gut health and inflammation Traditional Indian diets Protein myths Precision nutrition Timestamps 00:00 Introduction 01:00 Meet Shefaly Ravula 02:15 From Gastroenterology to Functional Medicine 05:30 Why Lifestyle Medicine Comes First 07:00 Precision Medicine vs Traditional Medicine 08:20 Why South Asians Develop Heart Disease Earlier 10:30 The Thrifty Gene Hypothesis 13:00 Why "Skinny" Doesn't Mean Healthy 15:15 The Muscle Deficit in South Asians 17:00 Continuous Glucose Monitors Explained 21:00 Why HbA1c Isn't Enough 23:30 Should Healthy People Wear CGMs? 26:30 The Functional Medicine Lab Panel 31:00 The Indian Diet Problem 38:00 Protein, Muscle & Longevity 41:00 White Rice vs Brown Rice 45:00 Cooking Oils: Seed Oils, Ghee & Olive Oil 50:00 Ancient Wisdom Meets Modern Science
Millions of people struggle with fatigue, weight gain, thyroid issues, insulin resistance, menopause symptoms, and hormone imbalance—but are we treating the symptoms instead of the root cause? In this episode of The Curious Cardiologist , Dr. Sanjay Bhojraj sits down with functional endocrinologist Dr. Saadia Mian to explore why conventional medicine often overlooks the deeper causes of hormone dysfunction and metabolic disease. Together they discuss: Why insulin resistance starts years before diabetes The connection between gut health and hormones Hashimoto's disease and thyroid dysfunction PCOS and metabolic health Menopause and hormone replacement therapy (HRT) GLP-1 medications like Ozempic and Wegovy Stress, cortisol and the hidden drivers of chronic illness Functional medicine versus conventional medicine Practical lifestyle changes that can dramatically improve hormone health Whether you're struggling with fatigue, stubborn weight gain, thyroid disease, menopause symptoms, or simply want to optimize your long-term health, this conversation provides a science-backed roadmap to understanding your body. Time Stamps 00:00 Introduction 01:15 Why Both Doctors Left Conventional Medicine 04:10 Dr. Saadia's Functional Medicine Journey 05:15 What Is Functional Endocrinology? 07:00 Hashimoto's & Autoimmune Thyroid Disease 09:00 Treating Root Causes Instead of Symptoms 10:45 Insulin Resistance & PCOS 13:15 Gut Health and Hormones 15:10 Functional Hormone Testing 18:25 Menopause & Hormone Replacement Therapy 22:45 Why Endocrinologists Aren't Trained in HRT 25:20 Hormone Therapy Safety 26:00 GLP-1 Medications Explained 30:00 Should Everyone Take Ozempic? 33:00 Trauma, Stress & Weight Gain 37:00 Functional Medicine vs Conventional Medicine 40:15 The Earliest Signs of Insulin Resistance 42:30 Three Lifestyle Changes That Improve Hormones 47:45 Artificial Sweeteners vs Sugar 51:00 Finding a Functional Endocrinologist 53:00 Why Insulin Resistance Is the Root Cause 54:30 Early Symptoms You Shouldn't Ignore 57:30 Rapid Fire Questions
Women account for nearly one in three cardiovascular deaths, yet many of the biggest risk factors are still overlooked. In this episode of The Curious Cardiologist , Dr. Sanjay Bhojraj sits down with functional medicine expert Cynthia Thurlow to discuss why women's cardiovascular health deserves a completely different approach. Together they explore the relationship between menopause, metabolic health, hormone replacement therapy, intermittent fasting, advanced cholesterol testing, GLP-1 medications, and personalized medicine. They discuss why traditional lipid panels often fail to identify cardiovascular risk, how pregnancy can reveal future metabolic disease, and why markers like ApoB and Lp(a) are transforming preventive cardiology. You'll also learn how fasting differs between men and women, why muscle preservation becomes increasingly important during menopause, and how physicians can move beyond one-size-fits-all medicine toward truly individualized care. Whether you're interested in heart health, hormones, longevity, metabolic health, or evidence-based functional medicine, this conversation offers practical insights grounded in both clinical experience and emerging research. Topics include: • Why heart disease remains the #1 killer of women • Menopause and cardiovascular disease • Hormone replacement therapy (HRT) • ApoB vs LDL • Lipoprotein(a) Lp(a) • Advanced lipid testing • GLP-1 medications beyond weight loss • Intermittent fasting for women • Muscle preservation during menopause • Personalized preventive cardiology If you're interested in functional medicine, longevity, metabolic health, women's hormones, or preventive cardiology, this conversation is packed with practical insights.
Can music become medicine? In this fascinating episode of The Curious Cardiologist , Dr. Sanjay Bhojraj speaks with Grammy-winning producer and author Barry Goldstein about the emerging science of Acousticeuticals™ —the intentional use of music to influence brain function, heart health, stress physiology, sleep, and emotional wellbeing. Barry explains how music affects the autonomic nervous system, heart rate variability, inflammation, cognition, and even our internal chemistry through dopamine, oxytocin, and cortisol. Together they explore ancient practices like chanting OM through the lens of modern neuroscience, discuss research on Alzheimer's disease and PTSD, and explain why certain tempos can literally entrain the heart and brain into healthier rhythms. The episode concludes with practical strategies anyone can use—including Barry's "Musical Nutrition" framework—to intentionally use music throughout the day for better health. Chapters / Time Stamps 00:00 Introduction: Can Music Become Medicine? 02:30 What are Acoustaceuticals? 05:20 Ancient Healing Meets Modern Science 09:00 The Neuroscience of Chanting OM 14:00 Alzheimer's Research & Memory Improvement 18:00 Drumming, PTSD & Inflammation 21:30 Heart Coherence Explained 26:00 Music, HRV & The Vagus Nerve 30:30 Why Noise Can Harm the Body 36:30 Ultrasound, Medicine & Future Therapies 41:00 Music's Effect on Hormones & Inflammation 45:00 How to Build a Daily Music Practice 51:00 Musical Nutrition: Morning, Midday & Evening 58:00 The Future of Acoustaceuticals 1:02:00 Rapid Fire Questions 1:07:00 Final Thoughts & Resources
Hair loss is often dismissed as a cosmetic issue—but what if it's actually one of your body's earliest warning signs? In this episode of the Curious Cardiologist Podcast, Dr. Sanjay Bhojraj sits down with Johanna Dahlman, founder of Alopecia Angel, to uncover the root causes of alopecia and why conventional medicine often falls short. After developing autoimmune alopecia in her early 30s, Johanna spent four years researching nutrition, functional medicine, lifestyle interventions, and autoimmune health before naturally restoring her hair. Today, she has helped thousands of people in more than 68 countries navigate hair loss by addressing the underlying drivers—not just the symptoms. Together, they discuss autoimmune disease, gut health, stress, genetics, medications, supplements, hormones, pregnancy, longevity, and why hair loss is often a sign that something deeper is happening inside the body. Whether you're experiencing hair loss yourself, supporting a loved one, or simply interested in preventative health, this conversation offers practical insights and a hopeful perspective. Topics discussed: ✔ What alopecia really is ✔ Autoimmune hair loss ✔ Functional medicine ✔ Gut health and the microbiome ✔ Stress and chronic inflammation ✔ Hormones and women's health ✔ DNA testing and personalized medicine ✔ Hair loss medications ✔ Supplements that may actually worsen hair loss ✔ Why "aging" isn't the whole story ✔ Hair regrowth through lifestyle changes Johanna also shares her personal journey of overcoming autoimmune alopecia naturally after being told there was no cure, and explains how that experience led her to help thousands of people worldwide. If you've ever wondered why you're losing your hair—or what your body might be trying to tell you—this episode is for you. 👍 Like, subscribe, and share if you found this conversation helpful. Timestamps 00:00 Introduction 01:20 Meet Johanna Dahlman 02:00 What Is Alopecia? 04:45 Johanna's Personal Hair Loss Story 08:00 Why Conventional Medicine Misses the Root Cause 10:30 The Functional Medicine Approach to Hair Loss 13:00 Healthcare Around the World 16:00 Is It Ever Too Early to Prevent Hair Loss? 18:30 DNA Testing & Personalized Medicine 20:00 Hidden Causes of Hair Loss 22:00 Breast Implants, Botox & Autoimmunity 24:30 Is Hair Loss Just Aging? 26:30 Can Exercise Improve Hair Growth? 28:00 Stress, Cortisol & Hair Loss 31:00 Diet, Nutrition & Protein 34:00 Medications That Cause Hair Loss 36:00 Supplements That May Be Making Things Worse 39:00 Gut Health & Autoimmune Disease 42:00 How Long Does Hair Regrowth Take? 45:00 Why There Isn't One Cure for Alopecia 47:30 Johanna's New Nonprofit Mission 50:00 Final Advice for Anyone Losing Their Hair 52:00 Rapid Fire Questions
What if the reason you feel tired, foggy, inflamed, or depleted isn’t stress, aging, or hormones… but something much more foundational? In this episode of The Curious Cardiologist Podcast , Dr. Sanjay Bhojraj sits down with Carol Allen, CEO and co-founder of Beam Minerals, to explore one of the most overlooked topics in modern health: minerals . Together, they unpack why mineral deficiencies may be contributing to fatigue, poor sleep, muscle cramps, hormone imbalance, brain fog, gut issues, stress resilience, and even mitochondrial dysfunction. They also dive into the science of humic and fulvic minerals , why delivery matters more than simply taking supplements, and whether modern food systems are leaving us fundamentally depleted. Topics covered include: In this episode: Why minerals are foundational to human health The connection between electrolytes, heart health, and energy Brain fog, fatigue, hormones, sleep & mineral depletion Why modern soil and food may be less nutrient dense The hidden problem with conventional electrolyte drinks Humic vs. fulvic minerals explained simply How minerals impact mitochondria and cellular energy Detoxification, glyphosate, heavy metals & environmental exposures Why some supplements don’t actually get into your cells What mineral testing can (and can’t) tell you Key Takeaway: You can’t build health on depleted foundations. Minerals may be one of the most overlooked pieces of the wellness puzzle. Chapters / Timestamps 00:00 – Introduction: Why minerals matter 02:45 – Fatigue, brain fog & hidden deficiencies 08:30 – Why food may no longer be enough 14:00 – Soil depletion & modern agriculture 24:30 – What are humic & fulvic minerals? 35:00 – How minerals actually get into cells 42:00 – The truth about electrolyte drinks 48:30 – Mineral testing: blood vs hair vs tissue 55:00 – The future of mineral replenishment 1:00:00 – Rapid fire questions
In this episode, Dr. Sanjay Bhojraj explores the decline of genuine doctor-patient connection, systemic issues in healthcare, and how a systems biology approach can transform medical practice. He shares personal experiences and insights on restoring empathy, curiosity, and holistic care in medicine. Interested in joining my U360 Membeship? Go to doctorsanjay.com to sign up! "When did doctors stop being doctors?" "Connection is more important than ever" "Inflammation drives most chronic diseases" Chapters 00:00 Welcome to Season Two 00:58 The Shift from Provider to Consumer 02:53 The Disconnection in Doctor-Patient Relationships 09:03 The Challenges of Modern Medicine 12:00 The Fragmentation of Care 17:48 The Importance of Lifestyle in Health 20:51 The Role of Curiosity and Listening in Medicine 27:00 The Future of Medicine: Connecting with Patients
In this episode of The Curious Cardiologist , Dr. Sanjay Bhojraj sits down with Dr. Shivani Gupta , PhD in Ayurvedic medicine, founder of Fusionary Formulas, and author of The Inflammation Code . Together, they explore why Ayurveda — a 5,000-year-old system of medicine — may be more relevant than ever in a modern world defined by chronic inflammation, burnout, disrupted circadian rhythms, and one-size-fits-all wellness trends. This conversation bridges ancient wisdom and modern science , reframing inflammation, gut health, sleep, fasting, and metabolic health through the lens of personalized, lifestyle-based medicine. If you’ve ever felt like you’re “doing all the right things” but still feel off — this episode is for you. 👇 Watch until the end for practical, simple ways to apply Ayurveda to your daily life. ⏱️ Chapters / Timestamps 00:01 – Welcome & introduction to Dr. Shivani Gupta 01:44 – What Ayurveda really is (and why it aligns with functional medicine) 02:57 – Doshas as the original personalized medicine 04:14 – Elemental Design: air, fire, earth explained 06:15 – Vata (air): anxiety, gut issues, grounding strategies 08:53 – Pitta (fire): inflammation, burnout, cooling the system 10:21 – Kapha (earth): metabolism, weight, mood, movement 12:36 – How seasons & life events shift your constitution 15:06 – Ayurveda vs genomics: two paths to personalization 18:20 – Why intermittent fasting & trends don’t work for everyone 22:44 – Why Ayurveda matters more than ever today 26:14 – Micro-rituals to reset the nervous system 29:17 – Tongue scraping, oil pulling, dry brushing, self-massage 35:34 – Food timing & the Ayurvedic circadian diet 37:41 – Super spices & the science of turmeric 50:46 – Supplement quality & why formulation matters 54:33 – Dr. Gupta’s Top 5 Ayurveda “Start Here” moves 59:01 – Rapid-fire questions (nachos, Italy, race cars) 01:01:54 – Where to find Dr. Gupta + listener discount 01:02:38 – Final thoughts & outro 🧠 What You’ll Learn in This Episode Why Ayurveda is the original root-cause & lifestyle medicine The three Ayurvedic constitutions (Vata, Pitta, Kapha) explained simply How circadian rhythm affects inflammation, digestion, and sleep Why some people feel worse with fasting, cold exposure, or extreme wellness trends Simple Ayurvedic rituals that support gut health, lymphatic flow, and nervous system regulation The real science behind turmeric and Ayurvedic “super spices” Why healing starts when you stop fighting your nature Practical Takeaways Dr. Gupta shares her Top 5 Ayurveda Moves anyone can start today : Learn your Elemental Design (Ayurvedic constitution) Use a copper tongue scraper daily Align your day with circadian rhythm & sunlight Protect sleep — especially the 10pm–2am window Use turmeric strategically to lower inflammation (with lifestyle support) 🔗 Guest Links & Resources Dr. Shivani Gupta – Website & Elemental Design Quiz 👉 https://shivanigupta.com Instagram 👉 https://www.instagram.com/doctor.shivanigupta Book: The Inflammation Code 👉 https://theinflammationcode.com (Also available on Amazon & Barnes & Noble) Supplements: Fusionary Formulas 👉 https://fusionaryformulas.com 🎟 Listener Discount Code: CURIOUS15 👉 15% off at checkout (mentioned in the episode) 👍 Support the Show If you found this episode helpful: Like the video Subscribe to The Curious Cardiologist Comment with topics or guests you’d like to see next
In this episode of The Curious Cardiologist , Dr. Sanjay Bhojraj sits down with Sandra Scheinbaum, PhD , founder and CEO of the Functional Medicine Coaching Academy (FMCA) , to explore why health coaching may be the most underutilized—and most powerful—tool in modern healthcare. Together, they unpack the growing gap between what doctors say and what patients actually do , why behavior change is so difficult even when people know what’s “right,” and how trained health coaches dramatically improve outcomes for chronic disease, mental health, and lifestyle-related conditions. Dr. Scheinbaum shares her journey from psychology and mind‑body medicine to founding FMCA, explains the science behind health coaching, and outlines how coaches integrate seamlessly into medical teams without replacing physicians. The conversation also tackles physician burnout, patient non‑adherence, Medicare reimbursement, and the future of collaborative care. This episode is essential listening for clinicians, health system leaders, coaches, and anyone interested in sustainable health transformation. Key Topics Covered Why the U.S. healthcare system struggles with outcomes despite record spending The communication gap between doctors and patients What health coaches actually do (and what they don’t) Why doctors are not trained to create behavior change The psychology of motivation, self‑efficacy, and lifestyle change Evidence and randomized trials supporting health coaching Health coaching for cardiometabolic disease, autoimmunity, mental health, and GLP‑1 users How health coaches reduce physician burnout Group coaching, community medicine, and peer support models Scope, certification, and avoiding “bad actors” in coaching Medicare reimbursement and collaborative care models Becoming a health coach: training, certification, and career paths Episode Show Notes Guest: Sandra Scheinbaum, PhD Founder & CEO, Functional Medicine Coaching Academy Certified through the Institute for Functional Medicine (IFM) What You’ll Learn Why knowledge alone doesn’t change behavior How health coaches increase adherence, outcomes, and patient satisfaction Why patients are often more honest with coaches than doctors The role of self‑efficacy in healing and long‑term health How lifestyle interventions can improve anxiety, depression, and quality of life Why community and accountability matter more than willpower Memorable Quotes “Doctors diagnose. Coaches help people change when change is hard.” “Genes are not destiny—daily habits matter more than people realize.” “Health coaching doesn’t replace medicine; it completes it.” Resources Mentioned Functional Medicine Coaching Academy: https://functionalmedicinecoaching.org National Board for Health & Wellness Coaching (NBHWC)
In this episode, Dr. Sanjay Bhojraj speaks with Dr. Jennifer Pfleghaar about her transition from emergency medicine to integrative medicine, focusing on the importance of lifestyle changes, the challenges of conventional medicine, and the need for personalized care, especially in women's health during perimenopause. They discuss the impact of pharmaceuticals, the role of hormones, and the significance of education in health. Dr. Jen also shares insights from her book, 'The Perimenopause Reset,' which aims to help women navigate this critical phase of life. Takeaways Dr. Jen transitioned to integrative medicine after seeing chronic disease in the ER. Conventional medicine often fails to address root causes of health issues. 90% of ER visits are related to chronic diseases. Hashimoto's thyroiditis can be reversed with lifestyle changes. Preventive care is lacking in the current healthcare system. Hormonal imbalances can significantly affect women's health. Bioidentical hormones are safer than synthetic alternatives. Education is crucial for patients to understand their health. Environmental factors can impact hormonal health. The Perimenopause Reset book provides a holistic approach to women's health. Chapters 00:00 Transitioning to Integrative Medicine 03:02 The Role of Nutrition in Emergency Medicine 06:11 Chronic Diseases and Conventional Medicine 08:46 The Disconnect in Patient Care 12:04 The Importance of Prevention 15:00 The Impact of Pharmaceuticals on Health 17:58 Motivational Interviewing in Patient Care 21:13 The Challenges of Hormone Replacement Therapy 23:57 Bioidentical Hormones vs. Synthetic Hormones 33:53 Understanding Hormonal Changes in Women 34:51 The Importance of Hormone Replacement Therapy 37:23 Navigating Hormone Testing and Medical Advice 38:03 The Risks of Self-Medication with Hormones 40:14 The Dangers of Hormone Pellets 43:32 The Need for Proper Medical Oversight 45:34 The Role of Continuous Learning in Medicine 51:01 The Holistic Approach to Perimenopause 54:11 The Impact of Environmental Factors on Hormones 56:41 Finding the Right Practitioner for Hormonal Health
In this episode of The Curious Cardiologist , Dr. Sanjay Bhojraj MD sits down with pharmacologist and genomic medicine specialist Dr. Tyler Panzner to unpack how your genes shape your response to diet, medications, and supplements. They explore the difference between genetics vs genomics , why one-size-fits-all nutrition advice (keto, carnivore, vegan) can be dangerous, and how polygenic risk scores and pathway-based genomics can guide truly precision nutrition and precision medicine . From vitamin D that never budges, to oxalate kidney stones, to why berberine may not be as “innocent” as Instagram says, this episode pulls back the curtain on the wild west of supplements . If you’ve ever wondered why your labs don’t change, why one cup of coffee wrecks you, or why your “clean” supplement stack makes you feel worse, this conversation is for you. Guest: Dr. Tyler Panzner Dr. Tyler Panzner, PhD is a pharmacologist specializing in genomic medicine and supplement pharmacology. He helps individuals and clinicians use comprehensive genomic data to personalize diet, lifestyle, and supplementation—focusing on bottom-up molecular pathways rather than fear-based, top-down disease labels. Website: drtylerpanzner.com Instagram / TikTok / YouTube / LinkedIn: @DrTylerPanzner [00:00] Welcome to The Curious Cardiologist & Guest Intro Dr. Sanjay Bhojraj MD introduces pharmacologist and genomic medicine specialist Dr. Tyler Panzner. [01:20] VHS, Blockbuster & the Hallmarks of Aging (Fun Cold Open) Light banter on VHS, rewinding tapes, and joking about “hallmarks of aging.” [02:25] Genetics vs Genomics: What’s the Difference? Tyler explains genetics (single variants) vs genomics (your entire genetic “book”) and polygenic risk scores. [04:30] Why One-Size-Fits-All Diets Fail: Keto, Carnivore, Vegan & Your Genes How saturated fat response, ancestry, and LDL genetics change who thrives or crashes on keto/carnivore. [08:40] Oxalates, Kidney Stones & Carnivore as a Tool (Not a Religion) Oxalate sensitivity, kidney stones, and why some people truly struggle with spinach and plant “defense chemicals.” [10:45] Vegan Fatigue, Conditional Amino Acids & “Have a Steak and See” Why some vegans feel amazing for 6–12 weeks, then crash when conditional amino acids run low. [12:35] Creatine, Carnitine, Iron & Taurine: When Your Genes Can’t Keep Up 9,400+ mutations tied to creatine production; why some people need more animal foods or very targeted supplements. [14:40] The Myth of Willpower, Food Noise & Micronutrient Deficiency How hormones and micronutrient gaps drive cravings, “food noise,” and self-blame. [17:40] “Loaded Gun vs Pulled Trigger”: Propensity, Transcriptome & Proteome Genes vs gene expression vs proteins—and why genotype ≠ destiny. [20:55] Bottom-Up Genomics: From Molecular Pathways to Real Symptoms Tyler’s “bottom-up” approach: focusing on linear pathways like glutathione, vitamin D, neurotransmitters, etc. [23:35] The Vitamin D Puzzle: CYP2R1, Low Levels & Why Your Labs Never Budge Chronic low vitamin D, CYP2R1 variants, gallbladder issues, and why megadoses sometimes don’t work—and may backfire. [28:25] Pharmacogenomics 101: COMT, MAO & Why Some People Hate Caffeine COMT and MAO variants, adrenaline sensitivity, and why some folks overthink, get anxious, or “overflow” on stimulants. [31:15] Supplements That Secretly Spike Adrenaline: Curcumin, Rhodiola, Berberine & More How “healthy” supplements (curcumin, resveratrol, quercetin, rhodiola, berberine, methylene blue) can trigger anxiety in sensitive people. [34:35] Berberine, CYP3A4 & Statins: Hidden Supplement–Drug Interactions Why berberine can affect CYP3A4, statin metabolism, and cardiometabolic patients. [35:55] Stacking 30 Supplements: Liver Strain & the Dark Side of “More Is Better” Tyler’s story of massive supplement stacks, elevated liver enzymes, and why “liver support” can still stress the liver. [47:50] Purity vs Pharmacology: The Two Sides of Supplement Safety Clean manufacturing vs how a supplement acts in your body: iron chelation, neurotransmitters, hormones, liver enzymes. [50:20] Big Pharma vs Big Wellness: Who’s Really Regulated? Comparing drug oversight to the “wild west” of AI-generated wellness brands and TikTok supplements. [57:00] How Tyler Actually Uses Supplements: Audits, Subtraction & Lifelong Bottlenecks Full supplement audits, using fewer products, and when something is truly lifelong (e.g., pre-activated vitamin D). [01:00:20] Supplements as Catalyst, Lifestyle as Foundation Using targeted supplements to get people out of a rut—but never as a replacement for sleep, movement, and real food. [01:01:55] Lightning Round: Favorite Food, Favorite Place, & What Keeps Tyler Curious Surf & turf, Tampa memories, and why he sees music as “acousticeuticals” and real epigenetic medicine. [01:04:40] How to Work with Dr. Tyler Panzner Where to find him online, plus how to think about genomic testing & interpretation. [01:06:30] Sanjay’s Final Thoughts & Call to Action How to choose good genomic testing, why interpretation matters, and where to subscribe and leave comments.
In this eye-opening episode of The Curious Cardiologist , Dr. Sanjay Bhojraj — a recovering interventional cardiologist turned functional medicine physician — sits down with Emily Sadri (APRN, CNM, WHP-BC), a nurse practitioner and certified nurse-midwife who has built a thriving hormone and metabolic health practice. Together they unpack the real story behind menopause, metabolic decline, and the cardiovascular consequences of ignoring hormone health. Emily shares her journey from hospital midwife to functional practitioner, the “aha” moment that meditation improved her gestational diabetes more than diet ever did, and how the Women’s Health Initiative (WHI) study derailed an entire generation’s access to hormone therapy. They explore: Why estrogen is far more than a “female hormone” — it’s a vascular, metabolic, and cognitive protector. How perimenopause is often the hidden root behind rising LDL, fatigue, anxiety, and weight gain. The difference between oral and transdermal hormones (and why route matters for heart health). How estrogen loss disrupts nitric oxide production, vagal tone, and even sleep and mood. Practical lab workups every woman in midlife should request. Why replacing hormones without fixing lifestyle is like “mopping up the ocean.” How functional and precision medicine can redefine women’s health and longevity. Emily and Sanjay weave humor, humility, and heart into a candid conversation that will change how you think about hormones — whether you’re a clinician, a patient, or a partner trying to understand what’s happening behind the scenes of midlife. 🧬 Key Takeaways Menopause isn’t a single event — it’s a 10–15-year metabolic and hormonal transition that starts in the 30s. Declining estrogen is directly tied to rising cardiovascular and metabolic risk. Transdermal estradiol + oral micronized progesterone remain the safest, most physiologic forms of HRT. Estrogen improves nitric-oxide production, insulin sensitivity, vagal tone, and arterial elasticity. Vaginal estrogen reduces UTI risk and supports the vaginal microbiome — even in breast-cancer survivors. The “menopausal machismo” mindset of “toughing it out” may actually shorten lifespan and healthspan. Functional medicine and hormone therapy must work together — lifestyle, nutrition, sleep, and stress are the foundation. 🧪 Guest Bio Emily Sadri, APRN, CNM, WHP-BC is a board-certified nurse practitioner, women’s health specialist, and former midwife who now leads Aurelia Health , a telehealth practice focused on personalized hormone therapy and metabolic medicine for women in midlife and beyond. Her mission is to redefine menopause care through education, precision hormones, and holistic root-cause healing. 🔗 Connect with Emily: Instagram → @EmilySadri_NP
Connect with Dr. Leon and MemoryAir at: https://learn.memoryair.com Summary In this episode of the Curious Cardiologist Podcast, Dr. Sanjay Bhojraj interviews Dr. Michael Leon about the groundbreaking MemoryAir device, which utilizes olfactory stimulation to enhance brain health and cognitive function. They discuss the science behind olfaction, its connection to memory and emotional centers in the brain, and how olfactory loss can precede cognitive decline in various neurological disorders. Dr. Leon shares insights from clinical studies demonstrating significant improvements in memory and mood through olfactory enrichment, particularly in older adults and children with autism. The conversation explores the potential applications of olfactory therapy in treating a range of health conditions and the importance of continued research in this innovative field. Takeaways The olfactory system has direct access to memory and emotional centers in the brain. Olfactory stimulation is crucial for maintaining brain health. Chronic inflammation is linked to olfactory dysfunction and cognitive decline. MemoryAir can significantly improve memory and mood in users. Olfactory loss is a common precursor to various neurological disorders. Pleasant odors can reduce inflammation in the brain. The device provides a passive way to receive olfactory enrichment during sleep. Children with autism showed remarkable improvements with olfactory therapy. Cognitive reserve can help prevent memory loss despite the presence of neurological damage. Future research may expand the applications of olfactory therapy beyond cognitive health. Chapters 00:00 Introduction to Olfactory System and Brain Health 02:50 The Importance of Olfactory Stimulation 08:37 Olfactory Loss and Cognitive Decline 09:58 Linking Olfactory Loss to Various Diseases 12:39 Quantifying Olfactory Ability 15:16 Pleasant vs. Unpleasant Smells 18:11 The Unique Role of Smell in Brain Health 20:16 Introduction to MemoryAir Device 22:55 Clinical Studies and Results of MemoryAir 25:51 Device Functionality and User Experience 26:04 Innovative Olfactory Therapy Device 27:04 Exploring Mental Health Benefits 28:32 Olfactory Enrichment in Autism Treatment 30:54 Cognitive Reserve and Memory Preservation 36:13 Olfactory Therapy for Brain Health 38:54 Future Frontiers in Olfactory Research 43:55 Commercial Availability and Practical Use
Why do some people never feel “back to normal” after COVID—or after any major illness—despite normal labs? Dr. Sanjay sits down with naturopathic physician and complex-illness specialist Jenny Tufenkian, ND to explore long COVID and myalgic encephalomyelitis/“chronic fatigue syndrome” (ME/CFS) : brain fog, fatigue, post-exertional malaise, mast cell activation, and the mental/emotional toll of being dismissed. They discuss root causes (viral reactivation, immune exhaustion, mitochondrial dysfunction, gut involvement), useful biomarkers (blood–brain barrier and neuroinflammation panels, lymphocyte mapping, herpes-family titers), and Jenny’s Five Foundations (digestion, detox, movement/breath & circadian rhythm, mindset/spirit, and connection). You’ll also hear practical starting points—sleep and gut first for many—and why joy, nature, laughter, and community are not “soft” add-ons but nervous-system medicine. Jenny previews her Long COVID 2.0 Summit featuring leading researchers and clinicians. Guest Jenny Tufenkian, ND — Naturopathic physician specializing for 20+ years in complex chronic illness, including long COVID and ME/CFS. She leads patient programs focused on root-cause healing and nervous-system regulation and hosts the Long COVID 2.0 Summit. Key topics & takeaways Why complex patients get “spit out” by the system : algorithmic care misses multi-system illness; dismissal often defaults to “it’s depression/anxiety.” ME/CFS clarified : better termed myalgic encephalomyelitis —neuro-immune inflammation affecting brain and muscle; symptoms wax and wane. Post-Exertional Malaise (PEM) : delayed crash (sometimes 72+ hours later); recognize patterns and “energy budgeting.” Vagus nerve & autonomic dysregulation : buzzing/vibration sensations, high sympathetic tone; mindset and breathwork matter. Viral reactivation : EBV/CMV/HHV-6 can hijack mitochondria and evade immunity; consider immune status (over/under-reactive). Useful labs (examples mentioned) : Neuroinflammation/BBB markers & Alzheimer’s-link panels (e.g., Cyrex). Immune/lymphocyte mapping and long-COVID panels (e.g., Immunosciences). Herpes-family titers; consider tau/other neurodegeneration biomarkers. Five Foundations : Digestion/Gut (COVID’s GI residency is common) Detoxification Movement & Breath / Circadian Rhythm & Sleep Mindset & Spirit Connection (to self, others, community; joy & laughter as therapy) Start where it moves the needle : sleep or gut for many; or choose the easiest win to build momentum. Joy is medicine : positive affect, nature, art, and play help downshift the nervous system, benefiting immunity and aging biology. Notable quotes (pull-quotes) “If you don’t fit neatly into a bucket, the system spits you out.” “Post-exertional malaise can be delayed—sometimes days later.” “Joy and connection aren’t extras; they’re nervous-system medicine.” “Be a detective: the path back is unique to each body.” Chapter markers (approx.) 00:00 Intro & why “complex” patients get lost 05:10 ME/CFS explained; gaslighting & the psych default 10:18 Brain & muscle inflammation; why root causes differ 16:06 Common symptoms, PEM, infections vs. vaccine patterns 17:30 Autonomic dysregulation, vagus sensations, stress loops 19:59 Delayed crashes & the trap of real-time correlations 22:10 Energy budgeting & the hidden life of patients 25:05 Joy, laughter, and neuro-immune health 27:58 The “gateway” HPA axis; stress addiction & culture 30:47 Mindset/spirit, nature, and connection as therapy 37:20 Biomarkers: BBB, neuroinflammation, viral panels, immune mapping 43:17 Treatment philosophy & Five Foundations 46:39 Long COVID 2.0 Summit preview 49:29 Rapid-fire: favorite places, food, curiosity Resources & links (add your URLs) Jenny’s Long COVID 2.0 Summit – https://drjennytufenkian.com/summit-2-0-registration/ref/28/
In this episode of The Curious Cardiologist Podcast , Dr. Sanjay Bhojraj sits down with Daniel Brown—aka “The Not Doc” —a real estate developer turned health thinker with a radical perspective: nearly all chronic illness can be traced back to lifestyle or emotions . Together, they dive into how our homes, lighting, water, and environment directly shape our health, and why paying attention to these often-overlooked factors may be just as important as diet and exercise. Daniel shares how he evolved from building houses to building healthier houses—and why feeling safe, supported, and aligned in your own space is essential for well-being. Highlights of the conversation include: 🏠 Healthy Homes : Why modern houses may be harming us—and the design tweaks that can restore balance. 💡 Light as Medicine : How artificial light disrupts circadian rhythms, hormones, and metabolism—and how to fix it. 💧 Water Wisdom : Filters, remineralization, and why your shower might matter more than your drinking glass. 🧠 The Power of Emotions : Daniel’s personal story of reversing autoimmune pain by addressing unresolved trauma. ⚡ Two Root Causes : Why most chronic disease comes down to lifestyle or emotional health—and how you can reclaim control. 🌱 Simple First Steps : From adding electrolytes to walking outside, unsexy habits often beat expensive hacks. This episode blends functional medicine, evolutionary biology, and real-world practicality into a fresh lens on what it truly means to live well. 🔗 Connect with Daniel Brown Instagram: @thenotdoc Twitter/X: @thenotdoc 🙌 Connect with Dr. Sanjay Instagram: @doctorsanjaymd Website: www.lagunamedicine.com Instagram: @doctorsanjaymd
In this episode of the Curious Cardiologist podcast, Dr. Sanjay Bhojraj and Dr. Spencer Zimmerman delve into the complexities of brain health, particularly focusing on postural orthostatic tachycardia syndrome (POTS) and its impact on cognitive function. They discuss the increasing prevalence of cognitive issues, especially in older populations and those recovering from long COVID. The conversation highlights the challenges patients face in the conventional medical system, including misdiagnosis and emotional distress. Dr. Zimmerman shares insights on the importance of early intervention, lifestyle changes, and the need for a holistic approach to treatment. The episode emphasizes the significance of understanding the interconnectedness of neurological, immune, and hormonal factors in managing conditions like POTS and cognitive decline. Chapters 00:00 Introduction to Brain Health and POTS 02:25 Understanding Cognitive Issues and Patient Experiences 07:23 Early Warning Signs of Cognitive Decline 11:34 Evaluating Cognitive Health: Tests and Assessments 14:25 The Importance of Balance in Cognitive Function 16:47 The Impact of Falls on Elderly Patients 19:29 Challenging the Concept of Age-Appropriate Health 20:40 The Effects of Concussions on Cognitive Health 24:09 Exploring POTS: Symptoms and Diagnosis 29:09 Demographics and Diagnosis of POTS 33:09 Emotional Toll of POTS on Patients and Families 34:40 The Importance of Movement in POTS 36:27 Understanding Diagnostic Criteria for POTS 43:15 Neuroimmune Disorder: The Dual Nature of POTS 49:37 Lifestyle Changes for Managing POTS 56:53 Intensive Retreats for POTS Patients Connect with Dr. Spencer Zimmerman: Instagram: @drspencerzimmerman WebsiteL https://drspencerzimmerman.com/
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