Pioneers of AI is your guide to the latest technological frontier. Each week, host Rana el Kaliouby (AI scientist, investor, author, co-founder of Affectiva) is joined by the leading creators, critics, and thinkers behind mind-blowing technology and asks the important questions about how artificial intelligence is changing the way we live. As we venture together into the unknown, Pioneers is your tool to understanding and anticipating what comes next.
For nearly two decades, Amy Webb's annual Tech Trends Report was required reading for anyone trying to keep up with technology. But this year, Webb killed the report and replaced it with something more applicable for leaders in an AI era. In this episode, CEO of Future Today Strategy Group Amy Webb joins host Rana el Kaliouby to unpack her 2026 Convergence Outlook and examines how AI-driven convergences such as compute shock, living intelligence, and emotional outsourcing will reshape business and daily life. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
Why AI conversations are always one-sided
39 min
Is it possible for us to ever wholeheartedly trust a machine the way we would a human? According to Charles Duhigg, Pulitzer Prize-winning journalist and New York Times bestselling author of The Power of Habit and Supercommunicators: How to Unlock the Secret Language of Connection, the answer is no. And that’s what stops us from being able to emotionally connect with AI chatbots. In this episode, host Rana el Kaliouby and Duhigg dissect what's really happening when people confide in ChatGPT and why real connection depends on reciprocity and vulnerability, two things AI can't offer. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
Rapid Response: The quiet reinvention of a $42b business, with Canva’s Cameron Adams
23 min
In the last year, Canva redefined itself from the ground up. Co-founder and Chief Product Officer Cameron Adams joins Rapid Response live from the Cannes Lions festival to explain why the so-called SaaSpocalypse never kept him up at night, how Canva shifted from a design company to an AI company without losing what made it great, and why being only 1% of the way there is actually the most exciting place to be. Adams also shares the specific steps anyone can take to get real impact from AI tools rather than just falling down the rabbit hole, and makes the case that in a world of commoditized models, your organization's unfair advantage is the only thing that matters. Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
WorkLab: Culture, not tech, softens AI’s impact
22 min
AI's promise is real. But the challenge to realizing its value isn't technology—it's people. Rana el Kaliouby joins WorkLab's Molly Wood to explore what can stall progress. The conversation explores how emotional intelligence, empathy, and communication are essential for hybrid human–AI teams to thrive. Rana makes the case that leaders must foster trust and readiness, rethink workflows, and keep humans at the center to unlock AI's full potential and ensure sustainable adoption. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
Stanford’s Silicon Valley pipeline, investigated
32 min
American universities are a critical pillar of US innovation. But what happens when Silicon Valley gets more intentional about that, treating a campus more like a talent pipeline, especially in the race to build AI? In his new New York Times bestseller “How to Rule the World,” journalist and recent Stanford graduate Theo Baker explores that and more. He describes the extreme lengths students and VCs go to in supercharging the school’s system for cultivating talent and investment opportunity. Host Rana el Kaliouby knows this world from the other side – as a founder who spun her company out of MIT and as an investor who now scouts talent on college campuses. Theo and Rana compare perspectives, discuss how AI has changed college, and ask whether AI is an accelerant to “win at all costs.” Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
What my kids taught me about the AI divide
46 min
It often feels like the world is divided when it comes to AI — do you lean in, or opt out?. But what if that tension exists within your own household? In this episode, Rana brings her kids onto the show for a candid conversation about AI adoption. Her son Adam is an AI enthusiast and her daughter Jana is an AI skeptic, a dynamic she wrote about in a recent essay, " I'm an AI Scientist, My Daughter Refuses to Use AI, and I'm Okay with It ." She asks them both to explain their different perspectives on AI, how they've embraced it and how they haven't — prompting Rana to reflect on her role as a mother and an AI leader raising both of them. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
AI on the pitch at The World Cup
32 min
At the 2026 FIFA World Cup, AI has already played a role in high stakes moments – revealing “just barely” violations that have broken hearts and driven hopes for millions of fans. As the tournament’s technology partner, Lenovo has augmented the game with new tools like virtual models of each player, balls equipped with motion sensors, and thousands of cameras logging every second of play. Lenovo Chief Information Officer Art Hu sat down with Rana just before the games began to share all the ways this World Cup draws a line between the pre-AI and post-AI eras of sports. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
Masters of Scale: IBM’s $10 billion bet on what comes after AI
41 min
While many tech companies race to build ever-larger AI models, IBM CEO Arvind Krishna sees the future differently. Speaking with host Bob Safian before a live audience during New York Tech Week, Krishna explains why enterprises are overcomplicating AI adoption, what kinds of risks leaders should be taking right now, and how to weigh AI's costs against its benefits. He also shares why IBM believes quantum computing will reshape the next era of technology. Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribe See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
Reid Hoffman says the AI race is not a cage match
35 min
Anthropic and OpenAI’s plans to go public have set off waves of speculation about the ripple effects, and how they’ll stack up to the SpaceX IPO. What’s really driving the value of these companies? Does the timing of the IPOs matter? How might they impact the AI startup ecosystem? To process all this, Rana phones a friend: Reid Hoffman. As co-founder of LinkedIn and Manas AI, a longtime Microsoft board member, investor in OpenAI and Anthropic, and so much more, Reid offers his take on the AI investing landscape. Rana and Reid break down the IPO headlines, sovereign wealth fund proposals for AI, and what’s defensible in AI today. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
What we risk losing to AI, w/ Natalie Monbiot
41 min
Natalie Monbiot is the founder of Virtual Human Economy (VHE) and was one of the first experts to advocate that your digital twin can be one of your most valuable assets. In fact, she argues that when we use AI models like ChatGPT and Claude, we are already creating a digital twin of ourselves. We welcome Natalie back to the show, following up on some topics we touched upon in our 2025 live taping at On Air Fest, “The making of an AI clone.” In this conversation, Rana and Natalie dive into what’s really at stake when we rely on AI for our thinking, what qualities make you indispensable at work, and what parts of ourselves we should not outsource to AI. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
Rapid Response: The race no one can win: AI’s anti-human crisis, with Aza Raskin
39 min
Big Tech is moving fast on AI. But who's watching out for the rest of us? Aza Raskin, co-founder of the Center for Humane Technology, has spent years sounding the alarm about where the race to build powerful AI is actually taking us. He joins Rapid Response to expose the incentive structures quietly pushing Silicon Valley toward dangerous territory, and to make the case that it's not too late to change course. Raskin also unpacks the significance of Pope Leo XIV's sweeping new encyclical on AI, what China's AI priorities reveal about the global race, and why the hidden assumptions baked into AI systems may be the most underestimated risk of all. Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
Does AI know you better than your doctor? w/ Ōura CEO Tom Hale
40 min
Historically, the only way to know what was going on in your body was to make a doctor’s appointment, run tests, and wait for the results. Now, wearable tech is changing access to health data. Rana sits down with Tom Hale, CEO of Ōura, the company behind the smart ring found on the fingers of everyone from elite athletes to patients managing chronic illness. Together they discuss how wearables give your body a voice, why and how Ōura is leaning into women’s health, and how a trifecta of sensors, data, and AI can move healthcare from reactive to preventive. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
Reimagining business school through AI with MasterClass CEO David Rogier
34 min
When MasterClass CEO David Rogier was a kid, his grandmother sat him down and told him how she'd lost everything during World War II. The lesson David took from her is that education is the one thing no one can ever take from you. That idea became the basis of the online learning platform he co-founded, MasterClass. Now, after celebrating its 10-year milestone, AI is leading David to reimagine what learning actually looks like. On this Pioneers of AI episode, David joins host Rana El Kaliouby in a frank conversation about how MasterClass hopes to upskill their audience with AI-driven offerings, how he is reimagining what business school can look like with AI, and how David himself is incorporating AI into his everyday CEO life. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
Rapid Response: Duolingo’s battle for learning in an AI world, with Luis von Ahn
31 min
When Duolingo CEO Luis von Ahn sent an internal memo about AI last year, he didn't expect it to go viral — or to ignite a firestorm about the future of work. Now he joins Rapid Response to unpack what he got right, what he got wrong, and what the backlash taught him about the real limitations of AI. Von Ahn also reveals why he's made a deliberate pivot in 2026: chasing users, not revenue — and what that bet says about how big Duolingo can get before ads become inevitable. It's a candid reckoning with hype, growth, and the surprisingly complicated promise of technology in education. Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
How fast can you upskill in AI? We did a sprint to find out.
34 min
We all feel the urgency: learn to use AI, or risk falling behind at work. And we all know there's an upside: AI can reduce tedious tasks, streamline operations, and boost output. But knowing is half the battle (maybe even less) and implementing AI needs to happen across an entire organization. So what does it take to start? Well, here at WaitWhat (the company behind this podcast!) we paused all operations for three days to find out. From editorial curation to visual design to event planning, we split into teams for an “AI Sprint.” And this Pioneers of AI episode takes you to the starting blocks on the track with us, as we test new tools, discover their limitations, and find where AI can deliver on its promise. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
Possible: Should we give AI a bank account?
57 min
This week, we're sharing something from our friends over at Possible. In this episode of Possible, Reid Hoffman and Aria Finger talk with Sean Neville, co-founder of Circle and architect of USDC, about building the financial infrastructure for an AI-driven economy. Now leading Catena Labs, Neville is working on what he calls the first AI-native bank —designed for autonomous agents that can transact, comply, and interact without humans in the loop. The conversation explores what breaks when AI tries to use today’s financial rails, why stablecoins may power machine-to-machine commerce, and why new concepts like “Know Your Agent” could become the foundation of trust in an AI financial system. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
I gave AI a year of my life: tech journalist Joanna Stern
39 min
It’s not easy to cover AI as a reporter when the technology moves so fast. Joanna Stern’s approach: learn by doing. For one year, the longtime Wall Street Journal tech reporter and Pulitzer Prize finalist embedded AI into every corner of her life: her doctor's office, her kids' toys, even her romantic relationships. (Her wife approved the last one.) Stern chronicles the experience in her new book, I Am Not a Robot , a perspective on consumer AI that's equal parts honest, funny, and hopeful. On this Pioneers of AI episode, Stern shares what her year with AI actually taught her. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
John Deere's AI vision for future farms
36 min
Tractors are smarter than you think. John Deere, the nearly 200-year-old company, is combining sensors, data, and machine learning in highly advanced vehicles and software to reinvent how the world grows food. On this Pioneers of AI episode, John Deere CTO Jahmy Hindman breaks down how AI is making farms faster, smarter, and more sustainable. Plus he shares his vision for a fully autonomous farm. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
ChatGPT doesn’t want you to email your ex
47 min
The rhetoric around AI tends to swing between doomerism and idealism, but the reality is much more nuanced. In this special live episode, Pioneers of AI turns the tables; MIT Sloan professor Sinan Aral interviews host Rana el Kaliouby and gets her candid perspective on the current state of AI. Dr. el Kaliouby makes the case for human-centric artificial intelligence that augments humans, rather than replace them. She also speaks frankly on the risks of a male dominated startup landscape, defends why AI needs EQ, and shares a piece of uncharacteristically critical advice she received from ChatGPT. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info .
