Giants Shoulder

🧠 JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/join Steven Barker is the chemist who has spent fifty years proving your brain makes its own psychedelic. He built the mass-spectrometry methods sensitive enough to find DMT in living tissue, and showed it sits in the brain at concentrations rivalling serotonin and dopamine. In 1981 the war on drugs cut his funding and the work stopped for fifteen years. He also synthesised his own supply — and took it. Expect to learn: - The locked cabinet: what his mentor kept behind two locks, and why Barker raided it - The missing neurotransmitter: why DMT meets every formal criterion and nobody noticed - Machine elves: why he calls the term marketing rather than science - DMT immunity: the lab technician who took a full dose and felt nothing - Receptors inside the neuron: the 2023 finding that explains the neuroplasticity SPONSORS Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial - https://app.macrofactor.com/mfgiants GS EPISODES MENTIONED Andrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDA Rick Strassman - Meet The Father Of Modern DMT Research: https://youtu.be/KeAZOj7tYsc Dennis McKenna - Dennis McKenna: "I've Spent 50 Years Investigating The Entities That Exist Within Ayahuasca": https://youtu.be/gTSBhfZhuD8 David Nichols - Meet The Greatest Living Psychedelic Scientist You've Never Heard Of: https://youtu.be/6umTgXsW1lQ GUEST LINKS ResearchGate Profile: https://www.researchgate.net/scientific-contributions/Steven-A-Barker-2164230436 N,N-Dimethyltryptamine, an Endogenous Hallucinogen (2018 review): https://doi.org/10.3389/fnins.2018.00536 A Critical Review of Endogenous DMT in Humans 1955-2010 (with Strassman): https://doi.org/10.1002/dta.422 LC/MS/MS Analysis of Rat Pineal Microdialysate (2013, the paper discussed on tape): https://doi.org/10.1002/bmc.2981 Administration of DMT in Psychedelic Therapeutics (2022 review): https://doi.org/10.1007/s00213-022-06065-0 LISTEN ON Spotify - https://open.spotify.com/show/5m3Gta5MtIYdk59pb2GJ7M Apple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249 SKOOL Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about FOLLOW EVAN https://x.com/evan_mcgl TIMESTAMPS 0:00:00 Trailer 0:02:15 50 Years Chasing One Molecule 0:06:37 Huxley, Osmond and the Birth of "Psychedelic" 0:08:01 The Schizotoxin Hypothesis That Started It All 0:10:54 Finding DMT in Everyone, Not Just Patients 0:11:56 How the War on Drugs Killed the Research 0:16:39 The 40 Years of Research We Lost 0:18:36 "Have You Ever Taken It Yourself?" 0:19:20 Inside the Locked Psychedelic Cabinet 0:20:22 The Overabundance He Didn't Want to Waste 0:22:51 Why He Won't Describe What He Saw 0:23:38 Set, Setting and the Expectancy Problem 0:27:16 Dennis McKenna Has Never Seen a Machine Elf 0:28:31 "Machine Elf" Was a Marketing Term 0:30:40 The Tryptamine Family Tree Explained 0:34:21 Bufotenine, 5-MeO-DMT and the Blood-Brain Barrier 0:38:36 DMT as a Working Neurotransmitter 0:41:34 "DMT Is the Missing Neurotransmitter" 0:44:56 You Have Two Brains - and the Gut Makes More 0:46:29 Pushing Back on Gallimore's Alien World 0:54:04 96% Say the Entity Was Conscious 0:57:52 Did the Caveman Experience an Alien? 0:59:07 "These Are Not Real Elves" 1:06:40 Are Some People Immune to DMT? 1:10:51 You Can't Build Tolerance to Your Own Neurotransmitter 1:15:46 The Receptors Hiding Inside Your Neurons 1:24:24 What a Psychedelic Overdose Actually Is .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇https://www.youtube.com/@thegiantsshoulder/joinAlexander Batthyány is the philosopher and psychologist who turned a deathbed anecdote into a science. He ran the first modern study of paradoxical lucidity, co-authored the field's founding definition with Bruce Greyson, and has now collected around 450 cases of severely demented patients unexpectedly getting their memory, speech and personality back. Victorian doctors documented the phenomenon at length and called it "lightening up before death"; twentieth-century medicine stopped writing it down because there was no way to phrase it in a case study. He is now working with a group at the Mayo Clinic to put cameras in patients' rooms so the episodes stop being missed. In one case a woman came back for two hours, discussed her own diagnosis, died — and imaging taken immediately afterwards showed no change whatsoever.SPONSORSGet One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqeGS EPISODES MENTIONEDRick Strassman - Meet The Father Of Modern DMT Research: https://youtu.be/KeAZOj7tYscAndrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDAGUEST LINKSX: https://x.com/Alxdr_BatthyanyGoogle Scholar: https://scholar.google.com/citations?user=VRL8CPYAAAAJPersonal Site: https://sites.google.com/view/alexanderbatthyany/startViktor Frankl Institute Vienna: https://www.viktorfrankl.org/Threshold (2023): https://us.macmillan.com/books/9781250782298/threshold/Psychology Today - Magic Mushrooms and Terminal Lucidity: https://www.psychologytoday.com/us/blog/consciousness-and-meaning-at-lifes-end/202607/magic-mushrooms-and-terminal-lucidityBatthyany & Greyson (2021), Spontaneous Remission of Dementia Before Death: https://med.virginia.edu/perceptual-studies/wp-content/uploads/sites/360/2021/04/terminal-lucidity-PC.pdfSKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:29 What Terminal Lucidity Actually Is0:05:33 Why He'd Rather Call It "Paradoxical Lucidity"0:06:01 "Call Your Grandma - She's Back Again"0:09:11 The Victorians Documented It, Then Medicine Stopped0:10:55 "We Saw It, But We Didn't Write It Down"0:12:58 Frankl's Rule: Treat Them As Fully Present0:17:35 What Brain Age Was She Speaking From?0:18:36 "It Was All As If In A Fog"0:21:11 The Wife Who Filmed It So People Would Believe Her0:25:40 The Art Historian Who Gave Back His Books0:30:27 Is It Comforting For Families, Or Crueller?0:32:02 The Three Shocks Every Family Goes Through0:38:05 450 Cases And Counting0:41:29 Does It Have Anything To Do With Death At All?0:45:12 Steven Pinker: "You're Seeing Figures In Clouds"0:47:10 "Everywhere And Nowhere"0:49:47 They Overdosed Her On Psilocybin. She Woke Up.0:51:37 She Got Her Sense Of Humour Back0:55:18 Dresden: The Brain Hadn't Changed At All0:56:37 "Some Of Our Personhood Is Platform Independent"1:02:40 Near-Death Experiences vs Paradoxical Lucidity1:05:52 Rick Strassman, DMT And Neuroprotection1:11:22 "How Can We Get Them Out?"1:20:20 When Vienna Gave Psychiatric Patients Malaria.....Email for sponsorship enquiries: evan@thegiantsshoulder.com

🧠 JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/join Carl Hart is a human drug scientist — the Mamie Phipps Clark Professor of Psychology in Psychiatry at Columbia University and Chair of its Department of Psychology, who runs one of the very few laboratories on earth licensed to give people real doses of crack cocaine, methamphetamine and MDMA. His volunteers live inside a sealed four-room lab for weeks at a time, originally built for NASA to study astronauts, with no contact with the outside world while he measures their sleep, their food intake and how much they speak. He started that work believing drugs were what had gone wrong in neighbourhoods like the one he grew up in. Thirty years of data refused to agree with him. Expect to learn why there is no such thing as drug addiction in a rat, why "hard drugs" is a category the human body doesn't recognise, why he refuses to use the word "psychedelic", how one extra methyl group is the only difference between methamphetamine and the main ingredient in Adderall, why psychiatry still runs on a theory formalised in 1967 when only six neurotransmitters were known, what heroin actually feels like and why the real danger is constipation rather than overdose, why addiction tracks access rather than pharmacology, and much more… SPONSORS Get Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulder GS EPISODES MENTIONED David Luke - Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://youtu.be/qLKD1gt1X5o GUEST LINKS Columbia Psychiatry Profile: https://www.columbiapsychiatry.org/profile/carl-hart-phd Personal Website: https://drcarlhart.com/ X: https://x.com/drcarlhart Drug Use for Grown-Ups: Chasing Liberty in the Land of Fear: https://en.wikipedia.org/wiki/Drug_Use_for_Grown-Ups High Price: A Neuroscientist's Journey of Self-Discovery: https://en.wikipedia.org/wiki/High_Price_(book) FOLLOW EVAN https://x.com/evan_mcgl TIMESTAMPS 0:00:00 Trailer 0:02:16 Why Human Rights Became His Whole Mission 0:03:45 "I Believed the Bullshit About Drugs" 0:07:42 The Brain-Imaging Studies That Prove Nothing 0:10:32 Why "Hard Drugs" Is a Made-Up Category 0:12:42 There Is No Such Thing as Addiction in a Rat 0:14:18 Put Cocaine on Your Gum and See What Happens 0:15:50 Rat Models for Autism, ADHD and Depression 0:18:03 How Many Hoops to Give a Human Crack Cocaine 0:20:38 "Psychedelic" Is a Political Word, Not a Real Thing 0:22:40 Why the One-Receptor Story Is Bullshit 0:23:56 Psychiatry Is Still Running on a 1967 Theory 0:31:17 One Methyl Group: Meth vs Adderall 0:34:41 The Lab NASA Built for Astronauts 0:37:45 The Phenomenology Gap Nobody Studies 0:39:01 "I Was a Virgin to These Drugs, And Not Even Curious" 0:44:14 What Heroin Actually Feels Like 0:47:04 The Real Danger Is Constipation 0:52:47 The Overdose Myth He's Trying to Destroy 0:55:39 Education, Not Harm Reduction 0:58:40 Addiction Isn't About Drugs, It's About Access 1:01:38 Not Whether to Legalise, But How 1:05:30 Dublin's Cocaine Problem, Evan Pushes Back 1:06:46 "That's Quite Arrogant of You" 1:09:05 The Same Argument That Delayed Emancipation 1:12:50 "We Put People on the Moon. This Is Not Complicated." .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing👇 https://www.youtube.com/@thegiantsshoulder/join Luca Turin is a biophysicist who has spent thirty years arguing that the nose reads a molecule's vibrations rather than its shape, published in Nature at twenty-three, and co-wrote the definitive critical guide to perfume with his wife Tania Sanchez. The vibrational theory of olfaction was declared dead twice before he revived it, and he is still waiting for the one experiment that would settle it. His newest result has nothing to do with smell: fruit flies sealed in separate opaque wells, with no sight, sound or scent between them, coordinate their movement anyway — and the coordination vanishes the moment the plate is made of metal. This is a scientist who went looking for anaesthesia and found something that looks like insect telepathy. Expect to learn why creating a smell stimulus is nothing like creating a colour, how a startup elicited smell sensations with ultrasound for the first time in history, why the only two chemical groups in the universe that share one vibration are also the only two that smell of rotten eggs, how a receptor could read vibrations with no lenses or prisms anywhere in your nose, why the famous "trillion smells" figure was a mathematical error, why nobody in pharmacology can predict what a drug will do once it binds, how Google Quantum AI's xenon question led to fruit flies, what happened when the plates were swapped for aluminium, why radio frequency would be the perfect brain-wide reward signal, and much more… SPONSORS Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial - https://app.macrofactor.com/mfgiants GS EPISODES MENTIONED Earl K Miller - Meet the MIT Neuroscientist Showing Brain Waves Are the Secret Engine Behind Consciousness: https://youtu.be/7OFb-NG3jIw Marjorie Woollacott - Neuroscientist: "Your Brain Doesn't Create Consciousness" — NDEs, Telepathy and Terminal Lucidity: https://youtu.be/mDWtmfmIUHA GUEST LINKS Google Scholar: https://scholar.google.com/citations?user=fgXXdQYAAAAJ Wi-Fly Project: https://wi-fly.eu/ X: https://x.com/LucaTurin Substack: https://lucaturin.substack.com YouTube: https://www.youtube.com/@lucaturin SKOOL Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about FOLLOW EVAN https://x.com/evan_mcgl TIMESTAMPS 0:00:00 Trailer 0:02:20 Biophysicists Are Dreamers, Biologists Are Doomed 0:07:07 The Startup That Triggered Smells With Ultrasound 0:12:22 The Rotten-Egg Coincidence That Convinced Him 0:18:34 What The Receptor Is Actually Reading 0:19:54 Electron Tunnelling, Explained Simply 0:23:33 The Trillion-Smells Figure Was A Maths Error 0:28:21 What Perfumers Perceive That You Don't 0:32:14 Why Every Drug Receptor Might Be Electrical 0:33:12 The Mystery Nobody Admits: Drug Efficacy 0:39:28 "Cascade" Is A Word That Masks Ignorance 0:44:04 The Receptor As A Transistor 0:48:40 Google Quantum AI And The Xenon Puzzle 0:52:24 Two Years Of Work, A Definite Maybe 0:53:55 30 Flies Freeze Like The Guards At Buckingham Palace 0:55:28 One Fly Per Well, No Way To Communicate 0:56:17 To My Total Astonishment, They Coordinate 0:58:45 Metal Plates Kill The Signal 0:59:36 The Wi-Fly: A Radio Network For Flies 1:11:26 Radical Pairs: How A Fly Could Listen 1:16:34 What Is The Brain's Reward Signal? 1:19:59 Standing Waves And The Binding Problem 1:23:58 Could Humans Ever Do This? 1:27:46 Ramanujan And Latent Abilities 1:36:16 Giving Fruit Flies DMT .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

🧠 JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/join Karen Konkoly is a dream scientist who led the first study to hold a real-time, two-way conversation with a person inside a dream, putting maths problems to sleepers in REM and getting answers back through their eye movements. She is a Marie Curie Postdoctoral Fellow in the Cambridge Consciousness and Cognition Laboratory, completed her PhD in the Paller Cognitive Neuroscience Laboratory at Northwestern University, and has spent her career building tools to engineer dreams — from targeted lucidity reactivation for narcolepsy nightmares to planting unsolved problems into REM sleep. She has also asked a dream character to swap bodies with her, and woken up inside it. This is the strangest conversation we have had on the channel. Expect to learn how scientists prove someone is awake inside a dream, why you still cannot fly in your own dream even when you know it is a dream, what happened when Karen swapped bodies with a dream character, whether time really slows down while you sleep, why practising darts in a lucid dream works about as well as practising awake, what galantamine and acetylcholine actually do to REM sleep, the exact protocol for having your first lucid dream, why Karen no longer believes lucidity is the key to consciousness, and much more… SPONSORS Get One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqe GS EPISODES MENTIONED David Spiegel - World's Greatest Hypnosis Scientist Hijacks My Mind Live On Camera!: https://youtu.be/eCtRBZHIsgQ GUEST LINKS Personal Website: https://www.karenkonkoly.com/ Google Scholar: https://scholar.google.com/citations?user=teYHEFIAAAAJ&hl=en Cambridge Consciousness & Cognition Lab: https://www.ccc-lab.org/ Dust Systems (Dream Engineering): https://www.dust.systems/people/karen-konkoly X: https://x.com/KarenKonkoly LISTEN ON Spotify - https://open.spotify.com/show/5m3Gta5MtIYdk59pb2GJ7M Apple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249 SKOOL Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about FOLLOW EVAN https://x.com/evan_mcgl TIMESTAMPS 0:00:00 Trailer 0:03:18 What Lucid Dreaming Actually Is 0:05:37 Wake Back To Bed: The 4am Method 0:06:40 Why You Still Can't Fly In Your Own Dream 0:09:20 How You Prove Someone Is Lucid In A Dream 0:11:53 Are The Sleep Stages Even Real? 0:15:28 When A Dream Dissolves But You Don't Wake Up 0:19:19 The Reality Check You Can Do Tonight 0:21:00 Does Time Run Slower Inside A Dream? 0:24:45 Trying And Failing To Become Her Dog 0:26:10 Swapping Bodies With A Dream Character 0:27:51 Is Lucidity A Glitch In Consciousness? 0:33:37 Hyperphantasia And Maladaptive Daydreaming 0:37:53 Practising Darts While You're Asleep 0:41:52 When Lucid Dreaming Is A Bad Idea 0:46:09 Why A Giraffe Can't Appear While You're Awake 0:49:54 Galantamine, Acetylcholine And Dream Drugs 0:52:17 The Squat Experiment 0:58:38 The Full Protocol, Step By Step 1:04:55 What This Teaches Us About Consciousness 1:09:15 Who Are Your Dream Characters? 1:12:55 "You're Not You" 1:14:41 Hypnosis, David Spiegel And Lucid Dreaming 1:18:20 What She's Working On Next .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

🧠 JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/join David Spiegel is the world's leading hypnosis scientist — fifty years at Stanford spent proving that trance is a measurable brain state rather than a stage trick, across thirteen books, four hundred papers and roughly seven thousand patients hypnotised personally. I told him to his face that I thought his entire field was a scam, so he ran the hypnotisability test on me live on camera, my left arm floated off the desk and stopped obeying me for the next forty minutes, and he scored me seven out of ten. Expect to learn what hypnosis actually is and the three components it breaks down into, how stage hypnotists secretly screen their audiences before the show even starts, what changes in three separate brain networks the moment you go under, why "suggestibility" is the wrong word and cognitive flexibility is the right one, how hypnotised subjects cut their brain's electrical response to pain by 50%, why one in four smokers quit after a single session, the two very different childhoods that both produce highly hypnotisable adults, why eight-year-olds are the most hypnotisable people alive, how Rory McIlroy used self-hypnosis to break a seven-year Masters curse, what it feels like to have your own arm stop belonging to you, and much more… SPONSORS Try Reveri, Dr David Spiegel's Self-Hypnosis App (use code SPIEGEL20 for your discount) - https://reverihealth.app.link/e/spiegel Get One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqe GUEST LINKS Stanford Profile: https://profiles.stanford.edu/david-spiegel Reveri: https://www.reveri.com/ Reveri on X: https://x.com/reveri_health Stanford Center on Stress and Health: https://med.stanford.edu/stresshealthcenter.html Trance and Treatment (his clinical textbook): https://www.appi.org/Products/Hypnosis/Trance-and-Treatment-Second-Edition SKOOL Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about FOLLOW EVAN https://x.com/evan_mcgl TIMESTAMPS 0:00:00 Trailer 0:02:27 Who Is David Spiegel? 0:03:39 What Hypnosis Actually Is 0:05:37 Why He Calls Stage Shows "Dumb Shows" 0:06:29 How Hypnotists Secretly Screen The Audience 0:09:08 The Student Who Relived Being A Newborn 0:10:46 What Hypnosis Does To Three Brain Networks 0:13:23 It's Not Suggestibility, It's Cognitive Flexibility 0:16:12 Cutting The Brain's Pain Signal By 50% 0:17:05 One In Four Quit Smoking In A Single Session 0:18:33 The Meditator Whose Migraines Vanished 0:22:36 Why Hypnotisability Is Partly Genetic 0:23:54 The Two Childhoods That Make You Hypnotisable 0:27:16 Hypnosis, Flow States And Peak Performance 0:32:54 How Rory McIlroy Broke His Masters Curse 0:38:05 Why You Can Forget Your Own Name 0:44:29 Filtering The Hurt Out Of Pain 0:55:00 The Hypnotisability Test, Live On Camera 1:00:15 "It's Actually Going Up" 1:08:52 Evan Scores 7 Out Of 10 1:18:42 Trying To Erase The Number Four 1:31:04 "Please Don't Do This On My Other Arm" .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

🧠 JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing: https://www.youtube.com/@thegiantsshoulder/join Rick Strassman is the psychiatrist who ran the first new American psychedelic research in a generation — five years of DMT studies at the University of New Mexico, the first rating scale ever built specifically to measure a psychedelic experience, and the book that made DMT famous. DMT: The Spirit Molecule sold a quarter of a million copies and effectively created machine-elf culture. Thirty years on, he is the most sceptical man in the room about what those entities actually are. Expect to learn why your brain spends energy importing DMT across the blood-brain barrier, why the pineal gland story he made famous fell apart, how brain DMT sits at the same concentration as serotonin and dopamine, why DMT floods the visual cortex of a dying brain, why a molecule that shrinks strokes and protects kidneys should not be psychedelic at all, what the endomatrix is and why it raises the simulation question, why he now thinks psychedelics are super placebos, what a DMT entity actually is and why talking to one is like talking to an AI, how you would actually test whether the entities are real, why only one scientist on Earth is studying endogenous DMT, and much more… SPONSORS Get Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulder Join the Outskill AI Mastery Sprint (Free This Weekend) - https://links.outskill.com/GIASHOULAUG2 GS EPISODES MENTIONED Steven Barker - Meet The World's Greatest Endogenous DMT Psychedelic Scientist You've Never Heard Of: https://youtu.be/gTc5QjyZuvY David Luke - Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://youtu.be/qLKD1gt1X5o Deborah Mash - Meet The Ibogaine Psychedelic Scientist Who First Unravelled Its Big Mystery: https://youtu.be/z7eRtXV6ptA Robin Carhart-Harris - No. 1 Psychedelic Scientist: The Entropic Brain Hypothesis, Consciousness & DMT Entities: https://youtu.be/t-GkE4YtLRk Andrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDA GUEST LINKS Official Site: https://www.rickstrassman.com/ Books & Publications: https://www.rickstrassman.com/publications/ Substack: https://rickstrassman.substack.com/ YouTube: https://youtube.com/c/RickStrassman Biosynthesis and Extracellular Concentrations of DMT in Mammalian Brain (Dean et al., Scientific Reports 2019): https://www.nature.com/articles/s41598-019-45812-w TIMESTAMPS 0:00:00 Trailer 0:04:31 The First Legal DMT Studies in a Generation 0:07:41 The Bomb-Maker Who Became a Psychedelic Scientist 0:14:13 The Iron Curtain Reason We Know DMT Works 0:22:32 Why Your Brain Spends Energy Importing DMT 0:28:26 Your Brain Makes DMT at Serotonin Levels 0:29:26 DMT Floods the Dying Brain's Visual Cortex 0:30:28 Stroke, Kidneys and Heart — DMT as a Survival Molecule 0:32:39 The $64,000 Question Nobody Can Answer 0:36:33 Does DMT Regulate How Real Reality Feels? 0:39:32 Only One Person on Earth Studies This 0:43:52 The Endomatrix and the Simulation Question 0:49:48 "Psychedelics Are Super Placebos" 0:55:12 The Man Who Wrote Down "Bananas Are Really Yellow" 1:03:50 The Barking Patient — Entities as Dream Logic 1:05:42 Talking to Entities Is Like Talking to an AI 1:06:40 The Prime Number Test for Proving Entities Are Real 1:13:36 Half His Volunteers Met Beings — And a Conscious Apartment 1:18:08 "Your Brain On Drugs" vs Another Dimension 1:26:58 The Entities That Curse You 1:29:09 "Have You Started Yet?" — The Man Immune to DMT 1:33:30 Why DMT Is the Only Psychedelic Without Tolerance 1:36:12 Blocking 5-HT1A Tripled the Effect — Buried 30 Years 1:39:06 Aphantasia and Seeing For the First Time .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

🧠 JOIN THE GIANT’S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing: https://www.youtube.com/@thegiantsshoulder/join Deborah Mash is a neuropharmacologist who holds the first FDA licence ever granted to give ibogaine to a human being, built one of America's largest brain banks, and discovered noribogaine — the metabolite now entering its first US clinical trial. She has spent over thirty years on a drug that appears to interrupt addiction after a single dose. This April a US president named it specifically. This is the scientist who was right three decades early. Expect to learn what Trump's executive order actually changes for ibogaine, why Sasha Shulgin put ibogaine in a box of its own, how noribogaine blocks nicotine, alcohol, cocaine and opioid use in animal models, why ibogaine holds the brain's neuroplasticity window open for four weeks when ketamine manages days, why some patients get the full therapeutic benefit with no psychedelic experience at all, why the reported ibogaine deaths are almost impossible to interpret, why more than 80% of her patients said they never wanted to repeat it, and much more... SPONSORS Get Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulder Join the Outskill AI Mastery Sprint (Free This Weekend) - https://links.outskill.com/GIASHOULAUG2GS EPISODES MENTIONED David Nutt - Meet the Neuroscientist Fired For Exposing the Truth! Dr David Nutt: https://youtu.be/BLk6a5Vb2O0 David Nutt - Neuroscientist Ranks Every Drug By How Hard They Are to Quit! Tier List: https://youtu.be/G-OZ_UBGvvo GUEST LINKS University of Miami Faculty Profile: http://neurology.med.miami.edu/about-us/faculty-list/deborah-c-mash-ph-d X: https://x.com/drdeborahmash Google Scholar: https://scholar.google.com/citations?user=4383E7wAAAAJ&hl=en DemeRx: https://www.demerx.com/team/deborah-c-mash-phd/ 2018 Frontiers in Pharmacology paper (St. Kitts cohort): https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2018.00529/full Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about FOLLOW EVAN https://x.com/evan_mcgl TIMESTAMPS 0:00:00 Trailer 0:02:00 Why Ibogaine Is Suddenly Everywhere 0:02:22 Trump's Executive Order and What It Actually Does 0:05:55 The Drug That Breaks the Cycle of Addiction 0:08:07 Why One Drug Treats Addiction, Depression and Trauma 0:11:30 Noribogaine: The Metabolite Nobody Talks About 0:14:20 The Real Risks Nobody Reports Properly 0:16:36 How Ibogaine Became a Vast Underground Experiment 0:17:44 Veterans, Brain Trauma and the Testimonials 0:22:55 The Master Molecule: Why Ibogaine Stands Alone 0:23:30 Sasha Shulgin Draws Four Boxes 0:26:48 Is a Psychedelic Just a Hard Reboot? 0:28:11 Four Weeks of Neuroplasticity, Longer Than Anything Else 0:28:44 Fast, Slow and Ultra-Rapid Metabolisers 0:31:39 The First Patient in St. Kitts, Decades Later 0:34:35 Do You Need the Trip to Reach the Destination? 0:35:05 One Molecule, Every Addiction 0:37:39 Miami Vice and the Bodies at the Morgue 0:41:18 The Man Who Slept Through His Own Trip 0:44:11 Why America Will Lead on Ibogaine 0:47:51 Dual Dosing: The Second Stage of the Rocket 0:54:52 Why More Than 80% Never Want to Repeat It 0:57:33 What Would Ibogaine Do to a Healthy Brain? 0:58:18 Why She's Never Taken Ibogaine 0:59:39 Psychedelics, Longevity and Ageing Brains ......Email for sponsorship enquiries: evan@thegiantsshoulder.com

Get Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulder Join the Outskill AI Mastery Sprint (Free This Weekend): https://links.outskill.com/GIASHOULAUG2 Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about Martin Picard is a mitochondrial psychobiologist at Columbia University who just won the inaugural $1.5 million Baszucki Prize for a new theory of life. His radical claim: consciousness doesn't just run on energy, it might actually be made of it, generated inside your mitochondria rather than your brain. Expect to learn why calling mitochondria "the powerhouse of the cell" does them a disservice, how mitochondria might generate consciousness rather than just power the brain that has it, why some of history's most rigorous physicists ended up believing consciousness is more fundamental than matter, how psychedelics might work by reshaping the way energy is patterned through your body, why grey hair can reverse itself within weeks of a stressful period lifting, how a simple blood test might one day predict whether you're about to have a good or bad trip, why "no drug actually heals you" and what does instead, and much more. Timestamps: 0:00:00 Trailer 0:02:00 What Actually Keeps You Alive (Not What You Think) 0:04:40 Why There's No Experience Without Energy Flow 0:07:11 Are You Conscious Because of Matter, or Despite It? 0:10:13 Why History's Greatest Physicists Became Idealists 0:17:17 The Doctor Who Watched Patients Come Back From Death 0:22:09 Don Hoffman and the Day the Beach Disappeared 0:24:12 What Actually Triggers a Near-Death Experience 0:24:51 You Are an Eddy in a River of Consciousness 0:31:59 Bernardo Kastrup's Idealism, Tested Live 0:33:34 Could We Scan Your Energy and Predict Your Mind? 0:39:37 Stop Calling Mitochondria "The Powerhouse" 0:40:03 Your Cells Are Basically Tiny GPUs 0:41:04 How Psychedelics Might Rewrite Your Energy Pattern 0:49:10 The Study Testing Whether Psilocybin Changes Your Mitochondria 0:52:06 "It's Not the Drug That Heals You"0:52:38 A Blood Test That Predicts Your Best (and Worst) Trip 0:57:27 The Psychedelic Paradox: Less Brain, More Experience 0:58:57 Aldous Huxley's "Reducing Valve" Theory of the Brain 1:02:03 "The Brain Is Overrated" ... Email for sponsorship enquiries: evan@thegiantsshoulder.com GS Episodes Mentioned: Robin Carhart-Harris - No. 1 Psychedelic Scientist: The Entropic Brain Hypothesis, Consciousness & DMT Entities: https://youtu.be/t-GkE4YtLRk Guest Links: Columbia Faculty Profile: https://www.columbiapsychiatry.org/profile/martin-picard-phd Personal Website: https://www.martinpicard.energy/ X (Twitter): https://x.com/MitoPsychoBio Google Scholar: https://scholar.google.com/citations?user=IG2t_uMAAAAJ&hl=en Mitochondrial Psychobiology Lab: https://www.picardlab.org

Try Mind Lab Pro, The Universal Nootropic For A Sharper Brain: https://www.mindlabpro.com/?a_aid=67fd1cb8d9ad3&a_bid=6d45f5c3 Join The Outskill Claude Mastery Sprint (2 Days, Free): https://links.outskill.com/GIASHOULAUG2 Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about Min Zhao is the UC Davis professor whose lab discovered the first genes ever found in electrical signalling — proof that every cell in your body runs on a current, not just your brain. He can reverse the polarity of a field and watch a living cell physically turn around and walk the other way. Expect to learn why every wound in your body generates its own measurable electric current, how a single postdoc's "failed" experiment revealed a force that overrides genetics, how reversing an electric field can make a cell physically turn around mid-migration, how a damaged potato generates the same electrical signal that guides wound healing in humans, why Min stops short of fully agreeing with Michael Levin on whether cells count as agents, and where the fight between bioelectricity and genetics currently stands. Timestamps 0:00:00 Trailer 0:02:20 What Everyone Gets Wrong About Wound Healing 0:07:20 Your Skin Is Secretly Electric (And So Is Everything Alive) 0:11:09 The 200-Year-Old Discovery Hiding in Every Wound 0:15:19 The Postdoc Result That Changed the Whole Lab 0:19:19 How Do Cells Know Where to Grow? (Five Fingers, Not Six) 0:21:19 The Potato Experiment That Reveals How Infections Start 0:25:24 Reverse the Field, Watch a Cell Turn Around 0:38:10 The Bioelectricity Nobody Taught in Biology Class 0:44:17 Is Bioelectricity More Fundamental Than Genes? 0:45:33 "No Electricity, No Life" 0:49:14 When Electric Fields Override Genetics Entirely 1:03:40 Michael Levin's Xenobots, Debated 1:12:22 Do Cells Have Agency? The Fuzziest Question in Biology 1:15:16 To Be Continued... (Members Get the Rest) ... Email for sponsorship enquiries: evan@thegiantsshoulder.com GS Episodes Mentioned Michael Levin — Michael Levin: Bioelectricity, Morphogenesis, Platonic Spaces & Xenobots: https://www.youtube.com/watch?v=LTBZRVKUwyM Philip Ball — Philip Ball: "Biology Is Infinitely Weirder Than We Thought": https://www.youtube.com/watch?v=9SseGx0R0fY Denis Noble — Denis Noble: Evolution Has Purpose, Cell Consciousness & Why The Last 70 Years of Genetics Is Wrong: https://www.youtube.com/watch?v=xqw-DaWVK24 Michael Levin & Earl Miller — Michael Levin & Earl Miller: Platonic Space of Minds, Bioelectricity, Cell Intelligence & Neurobots: https://www.youtube.com/watch?v=6mU5nN5nlLA Guest Links UC Davis Faculty Profile: https://health.ucdavis.edu/dermatology/faculty/zhao.html Zhao Lab (UC Davis Dermatology): https://health.ucdavis.edu/dermatology/research/lab/zhao.html Google Scholar: https://scholar.google.com/citations?user=G7-zWBcAAAAJ&hl=en Neuroengineering at UC Davis: https://neuroengineering.ucdavis.edu/people/min-zhao-md-phd UC Davis Profiles (Publications): https://profiles.ucdavis.edu/min.zhao

Get One Month Free of Consensus (The Best Ai Science Tool): https://get.consensus.app/we00d2cmjpqe Upgrade Your Shaving Experience With Henson (100 FREE BLADES): https://hensonshaving.com/thegiantsshoulder Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about Kirsten Cherian is the Stanford neuropsychologist who gave Special Forces veterans with traumatic brain injuries a single dose of ibogaine — a psychedelic root used in African shamanic ritual for millennia — and watched their injury scores collapse from severe to normal in a month. It's a weak agonist for nearly every receptor in the body, yet it somehow delivers a tailor-made result to each person — a form of pharmacology science has never seen before. Expect to learn why veteran suicide outpaces combat deaths, how one dose collapsed PTSD, depression, and anxiety at once, why users describe their brains being "defragged," a researcher's 12-hour "conversation" with the ibogaine molecule itself, the bizarre phenomenon of "DMT blocking" by hostile entities, why ibogaine has no single receptor target — "matrix pharmacology," how brain age dropped by over a year in a single month, and why the results contradict science's leading theory of consciousness. Timestamps 0:00:00 Trailer 0:02:11 How This Ibogaine Study For Veterans Began 0:04:06 Veteran Suicide Now Outpaces Combat Deaths 0:07:31 The 30-Veteran Study With Staggering Effect Sizes 0:12:22 Ibogaine Isn't A Trip, It's A Waking Dream 0:13:14 Vivid Trip Imagery: Slideshows And "Defragged" Brains 0:15:02 Reconciling Trauma By Talking To The Dead 0:20:01 What A Bad Ibogaine Trip Actually Looks Like 0:24:50 Purging "Black Demons" In A Room Full Of Strangers 0:27:23 The Scientist Who Talked To The Ibogaine Molecule 0:33:36 Why Elite Special Forces Veterans Still Broke 0:34:30 DMT Blocking: When Entities Refuse To Let You In 0:41:22 The Psilocybin Researcher Who Believes In Telepathy 0:43:00 Why Ibogaine Has No Single Target In The Brain 0:46:25 The 1920s Thought Experiment That Proves We're Too Skeptical 0:49:38 Ibogaine As A Full-System Diagnostic, Not A Drug 1:03:36 Measurable Brain Change From An African Tree Fruit 1:05:19 Brain Age Dropped Over A Year After One Dose 1:17:21 The Finding That Contradicts The Leading Theory Of Consciousness 1:20:28 If Ibogaine Research Got A Blank Billion-Dollar Check 1:23:21 Could Ibogaine Help Parkinson's And ALS Patients? ... Email for sponsorship enquiries: evan@thegiantsshoulder.com GS Episodes Mentioned Dalibor Sames — Meet The Greatest Ibogaine Psychedelic Scientist You've Never Heard Of: https://www.youtube.com/watch?v=K9whp_wtCoc Andrew Gallimore — No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://www.youtube.com/watch?v=USgWrxEFWDA David Luke — Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://www.youtube.com/watch?v=qLKD1gt1X5o Matthew Johnson — Consciousness Expert Explains The 5 Levels Of The Psilocybin Experience: https://www.youtube.com/watch?v=FHyy3aW09sk Robin Carhart-Harris — No. 1 Psychedelic Scientist: The Entropic Brain Hypothesis, Consciousness & DMT Entities: https://youtu.be/t-GkE4YtLRk Guest LinksStanford Profile: https://profiles.stanford.edu/kirsten-cherian Stanford Brain Stimulation Lab: https://bsl.stanford.edu/ MISTIC Study (Nature Medicine, 2024): https://pubmed.ncbi.nlm.nih.gov/38182784/ ResearchGate: https://www.researchgate.net/profile/Kirsten-Cherian VETS — Veterans Exploring Treatment Solutions: https://vetsolutions.org/

Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial: https://app.macrofactor.com/mfgiants Try Mind Lab Pro, The Universal Nootropic For A Sharper Brain: https://www.mindlabpro.com/?a_aid=67fd1cb8d9ad3&a_bid=6d45f5c3 Andrés Gómez Emilsson is a consciousness mathematician at the Qualia Research Institute, and he's back for round two of ranking altered states of consciousness by sheer intensity. He and Evan spend two hours ranking every substance and practice they can think of — arguing that ibogaine may be the most ethically urgent drug on Earth, that a hardcore meditation retreat can rival 5-MeO-DMT, and that an obscure nootropic produces psychedelic visuals through a mechanism nobody understands. Expect to learn why ibogaine seems to "scan" your whole nervous system instead of hitting one receptor, how advanced jhana meditation can go toe-to-toe with 5-MeO-DMT in depth, why ordinary DMT produces far more alien entity encounters than its "stronger" cousin, the topology behind why feeling like God and feeling like there's no self are almost the same state, why cannabis's real danger isn't addiction but a specific schizophrenia risk in young men, how combining LSD and ketamine produces "freewheeling hallucinations" you can consciously direct, why mescaline might be the best nootropic for doing actual math yet never caught on, and where MDMA, salvia, and a little-known nootropic called coluracetam land on the scale, and much more… Timestamps 0:02:53 Ibogaine 0:17:28 5-MeO-DMT 0:36:05 Meditation 0:46:33 DMT 0:58:41 Cannabis 1:05:15 Psilocybin 1:11:41 Ayahuasca 1:18:42 Coluracetam 1:21:09 MDMA 1:29:26 Salvia 1:44:21 Ketamine 1:54:37 Mescaline 1:58:48 LSD...... Email for sponsorship enquiries: evan@thegiantsshoulder.com Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about GS Episodes Mentioned David Nutt — Neuroscientist Ranks Every Drug By How Hard They Are to Quit! Tier List Part 2: https://www.youtube.com/watch?v=CEgbv6IHYaYMichael Levin & Earl Miller — Platonic Space of Minds, Bioelectricity, Cell Intelligence & Neurobots: https://www.youtube.com/watch?v=6mU5nN5nlLA Guest Links Qualia Research Institute: https://qri.org Qualia Computing (blog): https://qualiacomputing.com Substack: https://andrsgmezemilsson.substack.com X (Twitter): https://x.com/algekalipso

Upgrade Your Shaving Experience With Henson (100 FREE BLADES): https://hensonshaving.com/thegiantsshoulder Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about Dr. Reshanne Reeder is a cognitive neuroscientist at the University of Liverpool and creator of the Ganzflicker — a flickering screen that makes most people hallucinate complex scenes within a minute, no drugs required. Her research suggests hallucinations themselves are just disordered mental imagery, and that the most vividly imaginative among us may be the closest normal-range group to a psychotic break. Expect to learn why a simple red-and-black flicker makes most people hallucinate faces and landscapes within a minute, the accidental lab discovery that led to the Ganzflicker experiment, why she believes hallucinations are simply "disordered mental imagery," why psychedelic and clinical hallucinations come from entirely different brain mechanisms, the 1960s art device built to replace the television, why almost nobody hallucinates their own phone, how aphantasia may carry a hidden cost to face recognition, how she's trying to predict psychosis risk years before it ever develops, and much more… Timestamps 0:00:00 Trailer 0:02:29 How She Discovered Imagery Isn't One Thing 0:08:43 Can You Decode Images in an Aphantasic's Brain? 0:10:37 The Truth About "Unconscious" Mental Imagery 0:16:01 Imagery vs Imagination: Why They Aren't the Same Word 0:18:55 Imagery, Perception, Hallucination, Dreaming: Where's the Line? 0:20:36 The Hyperphantasics Who Project Images Into the Real World 0:22:23 Her Bold Claim: Hallucinations Are Disordered Imagery 0:23:37 Can Aphantasics Hallucinate on Psychedelics? 0:27:55 The DMT Study Where 90% Said It Felt More Real Than Reality 0:29:39 Why Mental Imagery Breaks the Predictive Brain Theory 0:32:21 The Irish Castle Test: Are Mental Images Just Priors? 0:38:58 She Made People See Faces in Pure Random Noise 0:42:04 The Illusion That Turns Faces Into Monsters 0:45:48 Why Aphantasia Might Come With a Face-Recognition Cost 0:47:35 His Sister Went 31 Years Without Knowing She Had Aphantasia 0:49:59 The Accidental Origin Story of Ganzflicker 0:51:26 The 1700s Origin of the "Whole Field" Hallucination Effect 0:57:41 "I See a Lighthouse": The Moment Ganzflicker Was Born 1:00:28 Why Aphantasics Barely Hallucinate on Ganzflicker 1:05:31 The Sharp Cliff Between Zero and Weak Mental Imagery 1:12:30 Why Nobody Hallucinates Their Phone 1:19:45 The Hypnosis Session That Left His Arm Frozen in the Air 1:22:13 The 1960s "Dream Machine" That Was Supposed to Replace TV 1:35:59 Can This Predict Psychosis Before It Happens? ... ... Email for sponsorship enquiries: evan@thegiantsshoulder.com GS Episodes Mentioned Adam Zeman — The Blind Mind's Eye: How Aphantasia Is Rewriting Consciousness ! Dr Adam Zeman: https://www.youtube.com/watch?v=SgA2up6-Bok Alfredo Spagna — Meet The Neuroscientist Proving We Got Imagination & Aphantasia WRONG!: https://www.youtube.com/watch?v=k8SBHefDnEk David Luke — Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://www.youtube.com/watch?v=qLKD1gt1X5o Karl Friston — Meet The Neuroscientist Who Created The Best Universal Theory Of Brain Function: https://www.youtube.com/watch?v=R-IZOFs4qmY Anil Seth — No. 1 Consciousness Expert: Optical Illusions that Prove Reality is a Lie, Emotions, Books and AI!: https://www.youtube.com/watch?v=lOSA06K0l1o Guest Links University of Liverpool Faculty Page: https://www.liverpool.ac.uk/people/reshanne-reeder Personal Website (Ganzflicker Demo): https://www.reshannereeder.com/ Bluesky: https://bsky.app/profile/kerblooee.bsky.social Google Scholar: https://scholar.google.com/citations?hl=en&user=DfdUB3UAAAAJ LinkedIn: https://uk.linkedin.com/in/reshanne-reeder-53182123b

Check out Scispace: (JNGIANT35: Get 35% off on the Max plan) https://scispace.com/?via=jun1giantshoulder Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about David Resnik is the NIH's Senior Advisor for Research Integrity and a philosopher of science who has spent his career defending careful, sober naturalism. He just co-authored a paper with biologist Michael Levin arguing that the shape of your body — and maybe your mind — is pulled from a nonphysical space of mathematical forms. Expect to learn why cicadas evolved to emerge only in prime-numbered years to dodge predators, why a mule's infertility comes down to simple odd-and-even chromosome math, why mathematics might be a "free lunch" baked into the universe rather than something we invented, why there may be no real difference between an electron and the equation that describes it, why Michael Levin's leap to calling certain mathematical forms "minds" might be the biggest jump in modern biology, why a Xenobot growing eyes and ears it doesn't need raises the question of where biological information actually comes from, why even a few lines of sorting-algorithm code can behave in ways nobody predicted, and why David thinks it might not matter whether Platonism is literally true, as long as it keeps producing good science. Timestamps 0:00:00 Trailer 0:02:52 Is Math Discovered or Invented? 0:15:48 Why Cicadas Emerge in Prime-Numbered Years 0:19:45 Why Mules Can't Reproduce (It's Just Math) 0:21:19 Michael Levin's "Free Lunch": Math That Isn't Physical 0:24:16 Is Materialism Actually Incomplete? 0:29:43 Xenobots: Where Did the Information Come From? 0:35:08 Why Do Xenobots Grow Ears and Eyes They Don't Need? 0:43:40 The Magnet and Iron Filings Experiment 0:45:26 Is There Really a Difference Between an Electron and Math? 0:46:40 Michael Levin's "Grand Canyon Jump" to Platonic Minds 0:48:03 What Is a Cognitive Light Cone? 0:54:26 Cutting a Triangle: What "Ingression" Actually Means 0:59:40 Michael Levin's Biological Compiler Idea 1:01:27 The Two-Headed Worm and the Eye That Shouldn't Exist 1:02:02 A Sorting Algorithm That Does the Unexpected 1:05:17 Laplace's Demon and the Limits of Prediction 1:09:43 Does It Matter If Platonic Space Is Real? 1:16:00 Could AI Access Minds Human Brains Can't? 1:17:36 The Limits of Any Mind in the Universe ... Email for sponsorship enquiries: evan@thegiantsshoulder.com GS Episodes Mentioned Michael Levin — Michael Levin: Bioelectricity, Morphogenesis, Platonic Spaces & Xenobots: https://youtu.be/LTBZRVKUwyM Michael Levin & Earl Miller — Meet the Scientist Showing Every Cell In Your Body is Conscious!: https://youtu.be/eNi-_2cOVtc Julian Barbour — Meet The Greatest Mathematician You've Never Heard Of: https://youtu.be/LcYdhjcFnzA Guest Links David Resnik — NIH Office of Intramural Research: https://oir.nih.gov/about/leadership-staff/david-resnik Levin & Resnik — "Mind Everywhere" Part One (Biological Theory): https://doi.org/10.1007/s13752-025-00523-6 Levin & Resnik — "Mind Everywhere" Part Two (Biological Theory): https://doi.org/10.1007/s13752-025-00524-5 David Resnik — ResearchGate: https://www.researchgate.net/profile/David-Resnik-2 David Resnik — NIEHS Bioethics: https://www.niehs.nih.gov/research/resources/bioethics/bioethicist

Upgrade Your Shaving Experience With Henson (100 FREE BLADES): https://hensonshaving.com/thegiantsshoulder Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about Elliot Murphy is a neurolinguist at UTHealth Houston who records language directly from inside the human brain, placing electrodes deep in the cortex of epilepsy patients and watching meaning get built in real time. His claim is unsettling: every time you speak, your brain performs an operation no other cognitive system — and no AI — can do, and the structure of grammar may be something the brain discovers rather than invents.Expect to learn why the phrase "old men and women" proves language breaks the laws of algebra, how "red boat" and "barco rojo" hide the same secret structure, what it means to record single words forming inside a living brain, why the deepest things you feel are impossible to put into words, how one word like "lunch" can be food, an event, and a time all at once, where Elliot stands on Michael Levin's idea that meaning lives in a Platonic space, why he thinks large language models don't understand a word they produce, what really separates human intelligence from pattern-matching, and much more… Timestamps 0:00:00 Trailer 0:01:56 From Liverpool Bookworm to Brain Scientist 0:10:25 The Phrase That Breaks the Laws of Logic 0:12:36 Why "Red Boat" and "Barco Rojo" Are Secretly Identical 0:15:14 Where Language Actually Lives in Your Brain 0:20:02 Recording Single Words Inside a Living Brain 0:23:38 The Surgery That Changed How We Study Language 0:36:12 Does Anything Else Work Like Language? Even Music? 0:40:28 The Feelings No Words Can Ever Reach 0:42:19 The Nietzsche Line Elliot Can't Shake 0:44:52 How "Lunch" Is Three Contradictory Things at Once 0:57:47 Does Meaning Have a Mathematical Shape? 1:03:34 Is Grammar Invented — or Discovered in a Platonic Space? 1:13:54 What Even Is Agency? 1:25:00 What Actually Separates You From an AI 1:30:12 Where to Start With Nietzsche and Dostoevsky... Email for sponsorship enquiries: evan@thegiantsshoulder.com GS Episodes Mentioned Michael Levin — Michael Levin: Bioelectricity, Morphogenesis, Platonic Spaces & Xenobots: https://www.youtube.com/watch?v=LTBZRVKUwyM Michael Levin & Earl Miller — Meet the Scientist Showing Every Cell In Your Body is Conscious!: https://www.youtube.com/watch?v=eNi-_2cOVtc Guest Links Elliot Murphy — Website: https://elliot-murphy.com Elliot Murphy — Google Scholar: https://scholar.google.co.uk/citations?user=4AYNRj0AAAAJ Elliot Murphy — UTHealth Profile: https://www.uth.edu/people/profile?id=a676259c-6b83-45de-bba3-f9ce464344a6

Try Mind Lab Pro, The Universal Nootropic For A Sharper Brain: https://www.mindlabpro.com/?a_aid=67fd1cb8d9ad3&a_bid=6d45f5c3Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutAdam Butler is a DMT researcher and author who has taken the molecule over 100 times and completed the same Monroe Institute consciousness program the CIA funded during the Cold War. He went from suicidal alcoholic to sober and mission-driven through a molecule his own brain already produces -- and then, one day, found himself completely locked out of the DMT space with zero pharmacological explanation for why.Expect to learn why DMT stops working for some people with no pharmacological explanation for it, how the body produces its own DMT internally, what the Monroe Institute's Hemi-Sync binaural beats protocol has in common with a DMT trip without any substance at all, why a declassified CIA-linked report took remote viewing seriously enough to fund it for decades, what DMT entities actually look like across 100+ trips, the controversial DMT laser experiment that claims to reveal a rigid code-like grid in the visual field, why effect sizes in psychedelic-assisted therapy trials are becoming impossible to ignore, and much more…Timestamps0:00:00 Trailer0:02:17 Who Is Adam Butler? From Rock Bottom to a Mission0:07:18 The Story That Changed Everything0:13:21 Inside His First DMT Session0:24:22 Why DMT Doesn't Build Tolerance0:31:56 Blocked: The Night DMT Just Stopped Working0:38:22 The Telepathy Tapes and the DMT Laser Experiment0:40:38 Huxley's Reducing Valve and the DMT "Cheat Code"0:44:29 What Is a DMT Entity, Really?0:48:21 Jesters, Mantis Beings, and the Entity Portfolio0:54:48 Carhart-Harris's Theory vs Alien World-Building1:02:52 Do DMT Entities Have Their Own Agency?1:09:20 The Mantis "Technicians" and the Body Upgrade1:11:23 Meeting His Future Self on DMT1:17:28 Inside the Monroe Institute1:32:17 The Declassified CIA Gateway Project1:41:10 Temporal Lobe Epilepsy and DMT-Like States1:44:27 The DMT Laser Experiment Explained1:53:21 Debating the "Code of the Simulation" Claim1:58:37 Near-Death Experience and Why It All Matters... Email for sponsorship enquiries: evan@thegiantsshoulder.comGS Episodes Mentioned:Robin Carhart-Harris — No. 1 Psychedelic Scientist: The Entropic Brain Hypothesis, Consciousness & DMT Entities: https://youtu.be/t-GkE4YtLRkAndrew Gallimore — No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://www.youtube.com/watch?v=USgWrxEFWDAAndrés Gómez Emilsson — Consciousness Expert Explains The 6 Levels Of The DMT Experience: https://youtu.be/xMdl7zF2MWEGuest Links:Instagram: https://www.instagram.com/booksbyadambutlerYouTube: https://www.youtube.com/@ButlersDMTFieldGuidePatreon: https://www.patreon.com/BooksByAdamButlerBook — Butler's DMT Field Guide: https://www.amazon.com/dp/196050505XBook — Butler's Psychedelic Integration Field Guide: https://www.amazon.com/dp/B0H4GL8H6V...Email for sponsorship enquiries: evan@thegiantsshoulder.com

Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial: https://onelink.to/giants Get Manta Sleep Mask: https://bit.ly/4ilzfBL and Code GIANTSMANTA10Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about Dalibor Sames is the chemist who reverse-engineered ibogaine into a version that appears to erase heroin addiction in a single dose, without the cardiac risk that can kill people on the original drug. He also took his own medicine — and says he watched the molecule's exact 3D structure rotate in front of him for 36 hours straight.Expect to learn why ibogaine breaks every rule of classical pharmacology, what "matrix pharmacology" means and why it's heresy to a one-drug-one-target industry, how editing a single atom deletes ibogaine's fatal heart risk, why a common antidepressant turned out to be a secret opioid for thirty years, what it's like to watch a molecule's structure appear during a 36-hour flood dose, why ibogaine seems to erase interest in alcohol overnight, whether the "DMT block" phenomenon researchers describe is real, and much more… Timestamps0:00:00 Trailer0:02:39 Meet the Chemist Who Fell for a Molecule's Shape 0:04:13 The Dogma That the Adult Brain Can't Heal0:09:00 Why Synapses Might Explain Every Brain Disorder0:10:28 Reverse-Engineering Nature's Own Drugs 0:16:44 The Paper That Changed Everything About Addiction 0:20:01 Why Ibogaine Breaks Every Rule of Pharmacology 0:33:08 The Weakest Drug That Works the Strongest 0:38:21 The Traffic Jam That Explains Matrix Pharmacology 0:44:18 A Human Genome Project — For One Molecule 0:47:48 Deciding to Take Ibogaine Himself 0:50:02 Inside a 36-Hour Flood Dose 0:54:38 The Chapter Called "Treatment" 0:56:26 Ibogaine Shows Him the Future of Design 1:00:01 Seeing Ibogaine's 3D Molecular Structure 1:03:14 High-Fiving a Molecule1:06:47 "This Is a Computational Technology" 1:16:36 The Simulation So Real It Panicked Him 1:24:26 Did He Earn This Experience? 1:30:56 Six Months Later — What Actually Changed 1:36:01 Did This Change His View of Consciousness?...... Email for sponsorship enquiries: evan@thegiantsshoulder.com GS Episodes Mentioned Andrew Gallimore — No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://www.youtube.com/watch?v=USgWrxEFWDA David Luke — Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://www.youtube.com/watch?v=qLKD1gt1X5oGuest LinksColumbia Chemistry faculty page: https://www.chem.columbia.edu/content/dalibor-sames Sames Lab: https://www.samesgroup.org/professor-dalibor-sames Gilgamesh Pharmaceuticals: https://www.gilgameshpharmaceutical.com/ Oxa-Iboga paper (Nature Communications, 2024): https://doi.org/10.1038/s41467-024-51856-y Beond Ibogaine Clinic (where he took ibogaine): https://beondibogaine.com

Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial: https://onelink.to/giants Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about Dráulio Barros de Araújo is a physicist who spent twenty years pointing MRI scanners at the ayahuasca experience, and ran the world's first controlled trial proving a single dose of a psychedelic could lift treatment-resistant depression in a week. He thinks DMT entity encounters are not hallucinations, and he wants to know if they could be real.Expect to learn why calling ayahuasca visions "hallucinations" is scientifically wrong, why you can't overdose or build tolerance to ayahuasca the way you can with alcohol or cocaine, why vomiting is considered part of the medicine rather than a side effect, how a physicist measured the entropy of a mystical experience and watched it rise, why your eyes physically won't stay open during a vision, the hippocampal memory glitch that may explain why DMT entities feel real, and why psychedelic science may be measuring altered states with the wrong tools entirely. Timestamps 0:00:00 Trailer 0:02:50 Who Is the Physicist Studying Ayahuasca Visions 0:05:05 The 1930s Origin of Brazil's Ayahuasca Churches 0:10:13 Why You Can't Buy Ayahuasca Like a Coca-Cola 0:11:22 What a Typical Ayahuasca Trip Actually Feels Like 0:16:53 Why LSD Visions Happen With Eyes Open, Ayahuasca Doesn't 0:17:22 Your Brain on Ayahuasca Looks Like a Dream, Not a Hallucination 0:21:08 Why Ayahuasca Visions Never Feel Like "Just a Dream" 0:22:23 There's No Such Thing as an Ayahuasca Overdose 0:24:18 Why Vomiting and Diarrhea Are Part of the Medicine 0:28:34 The Hippocampus Theory of Why DMT Entities Feel Real 0:33:22 Would Irish People See Snakes on Ayahuasca Too? 0:35:40 We're Measuring Trips With the Wrong Scientific Tools 0:40:44 Speech Analysis: A New Way to Study the Trip 0:44:31 The Flawed Questionnaire Behind Every Psychedelic Study 0:50:23 Why Dráulio Refuses to Ask a Single Direct Question 0:55:19 The Entropic Brain Hypothesis, Explained by a Physicist 1:02:01 Why Psychedelics Dissolve Your Career Ambitions 1:04:02 The Most Important Psychedelic Question Science Avoids: Death 1:06:09 What the West Should Learn From Indigenous Ayahuasca Traditions... Email for sponsorship enquiries: evan@thegiantsshoulder.com GS Episodes Mentioned David Luke — Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://www.youtube.com/watch?v=qLKD1gt1X5o Robin Carhart-Harris — No. 1 Psychedelic Scientist: The Entropic Brain Hypothesis, Consciousness & DMT Entities: https://www.youtube.com/watch?v=t-GkE4YtLRk David Nutt — Neuroscientist Ranks Every Drug By How Hard They Are to Quit! Tier List Part 2: https://www.youtube.com/watch?v=CEgbv6IHYaY Guest Links UFRN Brain Institute — Faculty Profile: https://neuro.ufrn.br/institute/members/investigators/draulio Google Scholar: https://scholar.google.com/citations?user=NoO4Rt0AAAAJ Centro Avançado de Medicina Psicodélica (CAMP): https://www.camp-sci.com/ptLinkedIn: https://www.linkedin.com/in/draulio-araujo-06ab47125

Get Manta Sleep Mask: https://bit.ly/4ilzfBL and Code GIANTSMANTA10 Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about Dennis McKenna is an ethnopharmacologist who spent fifty years decoding the chemistry of psychedelic plants, producing the first hard pharmacological proof of why ayahuasca actually works. He's also the younger brother of Terence McKenna, and in 1971 the two of them ran an experiment on their own minds in the Colombian Amazon that ended in a two-week psychotic break neither has ever fully explained.Expect to learn why the McKenna brothers thought DMT was a portal to another dimension rather than a drug trip, what happened during Dennis's two-week dissociation from reality in the Amazon, how ayahuasca's DMT and MAO-inhibitor plants actually work together in the body, why Dennis still calls the entire 1971 expedition "an act of science fiction, not science," how his PhD research became the first pharmacological proof of why ayahuasca works, why he thinks his own brother unintentionally seeded the "machine elf" into everyone else's DMT trips, why a career pharmacologist has never personally seen one himself, and why DMT entity encounters may be linked to real mental health outcomes, and much more… Timestamps 0:00:00 Trailer 0:03:07 How Dennis Got Into Psychedelics 0:06:07 Terence The Philosopher vs Dennis The Scientist 0:11:11 The 1971 Expedition To The Colombian Amazon 0:16:05 Why DMT Was "The Holy Grail" 0:17:50 The Ayahuasca Chemistry Nobody Understood Yet 0:18:45 Hunting For The Legendary Oo-Koo-Hé 0:22:00 Stumbling Into A Mushroom Paradise 0:27:05 When The Mushrooms Started "Talking" 0:28:38 The DNA Resonance Experiment 0:36:01 The Two-Week Psychotic Break 0:40:46 Psychotic Break, Shamanic Initiation, Or Alien Encounter? 0:47:08 From Psychotic Break Back To The Lab 0:53:16 Proving How Ayahuasca Actually Works 0:58:47 The Book That Seeded Mushrooms Into Society 1:05:39 Sasha Shulgin And The Chemistry Of Psychedelics 1:11:02 "I've Never Seen A Machine Elf Myself" 1:17:56 Pushing The DMT Experience To Five Hours 1:20:02 What Makes DMT Different From Psilocybin 1:26:18 DMT Entities And Mental Health Outcomes...... Email for sponsorship enquiries: evan@thegiantsshoulder.comGS Episodes MentionedAndrew Gallimore — No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://www.youtube.com/watch?v=USgWrxEFWDA David Luke — Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://www.youtube.com/watch?v=qLKD1gt1X5oGuest Links Heffter Research Institute Bio: https://www.heffter.org/dennis-j-mckenna-phd/ McKenna Academy of Natural Philosophy: https://mckenna.academy/mka-team/dennis-mckenna/ X: https://x.com/DennisMcKenna4Book — The Brotherhood of the Screaming Abyss: http://brotherhoodofthescreamingabyss.com/ ResearchGate: https://www.researchgate.net/profile/Dennis-Mckenna

Get Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulder Get Manta Sleep Mask: https://bit.ly/4ilzfBL and Code GIANTSMANTA10 Denis Noble is the physiologist who built the first computer model of the heart in 1960 — and has spent the sixty years since using it to dismantle the gene-centric view of life that dominates modern biology. He took Richard Dawkins's Selfish Gene and rewrote its most famous passage word for word in reverse — and every single experiment still fits.Expect to learn why the central dogma of molecular biology is provably wrong, how your immune system rewrites its own DNA to fight off new viruses, why the peppered moth story in every biology textbook turns out to be false, what happened when Denis told Richard Dawkins "Lamarck is back" to his face, why a cell corrects roughly 800,000 DNA replication errors before it's allowed to divide, how epigenetic inheritance can persist indefinitely if the environment stays changed, whether plants might have a form of experience, and where exactly agency ends and pure chemistry begins. Timestamps 0:00:00 Trailer 0:02:27 Meet The Man Who Modeled The Heart By Hand 0:04:43 Why The Central Dogma Of Biology Is Wrong 0:06:39 The 1866 Split Between Darwin And Wallace 0:09:02 The Infinite Monkey Theorem, Tested For Real 0:17:30 The Peppered Moth Myth Textbooks Still Teach 0:20:19 The Nobel Laureate Textbooks Forgot To Cite 0:22:53 Telling Richard Dawkins "Lamarck Is Back" 0:27:43 Was Lamarck's Giraffe Neck Story Actually Right? 0:29:40 How Your Body Talks To Your DNA 0:38:17 A New Species Evolved In Two Generations 0:44:18 So What's Actually Controversial Here? 0:48:09 Cellular Agency: When Cells Act Like Organisms 0:53:04 Steelmanning The Case Against Cellular Agency 0:55:05 The 17th-Century Prediction That Proved Purpose Works 1:04:20 Your Cells Correct 800,000 DNA Errors Per Division 1:13:14 Life Lives On The Edge Of Order And Chaos 1:15:27 Do Plants Have Experience? 1:27:31 How Does Consciousness Fit Into Systems Biology?...... Email for sponsorship enquiries: evan@thegiantsshoulder.com GS Episodes Mentioned Michael Levin — Meet the Scientist Creating New Forms of Synthetic Life! Dr Michael Levin: https://www.youtube.com/watch?v=LTBZRVKUwyM Philip Ball — Philip Ball: "Biology Is Infinitely Weirder Than We Thought": https://www.youtube.com/watch?v=9SseGx0R0fY Guest Links Oxford Faculty Page: https://www.dpag.ox.ac.uk/team/denis-noblePersonal Website: https://www.denisnoble.com Google Scholar: https://scholar.google.com/citations?user=J6kLmsIAAAAJ&hl=en Understanding Living Systems (Book): https://www.amazon.com/Understanding-Living-Systems-Life/dp/1009277367 The Third Way of Evolution: https://www.thethirdwayofevolution.com/people/view/denis-noble