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Neuroscientist and author David Eagleman discusses how our brain interprets the world and what that means for us. Through storytelling, research, interviews, and experiments, David Eagleman tackles wild questions that illuminate new facets of our lives and our realities.
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This week we reach into the archive for one of the most popular episodes of Inner Cosmos. Why do birds and bees choose different flowers? Why do mammals' eyes seem to be optimized for moving around at night, and what does that have to do with hairless humans getting angry? What does any of this have to do with road signs, camouflage, mantis shrimp, the sun, the dress that broke the internet, and women who can see more colors than you can?
Is your personality written into the circuitry of your brain? With brain disease, can someone lose who they are without realizing it? What happens when the person changing is the only one who can't see it? What does it mean to love someone whose personality has become unrecognizable? If you carried a genetic mutation that would alter your brain in the near future, would you want to know? Join Eagleman with bestselling author Robert Kolker to discuss these questions in the context of his new book about frontotemporal dementia, The Vanishing Family .
How do you get trillions of cells to collaborate as the single organism that we call you ? Does that kind of cooperation create opportunities for hijacking -- for example, is cancer a form of "cellular cheating"? Can we take the lessons learned from biology and apply them to understanding politics? And what do models of cooperation tell us about building and living with AI? Join Eagleman with evolutionary biologist and cooperation theorist Athena Aktipis to understand cooperation and competition from cells to societies to our technological future.
This week we reach into the archive for one of the most popular episodes of Inner Cosmos. Why do brains dream, and why are dreams so bizarre? Why doesn't your clock work in your dreams? And even though you spend much of your working day looking at your cell phone and computer – why do they almost never make appearances in your dream content? Is dream content the same across cultures and across time? Are dreams experienced in black & white, or in color? Are dreams the strange love child of brain plasticity and the rotation of the planet? What is the relationship between schizophrenia and dreaming? In the future, will we be able to read out the content of somebody's dream? Join Eagleman this week to learn why and how we spend a fraction of our sleep time locked in different realities, swimming in plots which aren't real but which compel us entirely nonetheless.
What's a feeling for? What is jealousy measuring and motivating? Why do both awe and grief slow us down? What happens when ancient emotions meet dating apps and like buttons? Does the intensity of a feeling decide which part of you takes control? Can understanding an emotion loosen its grip? Today we sit down with evolutionary psychologist Robert Kurzban to understand the logic behind the our varied panoply of emotions.
Can your smartwatch detect subtle changes before you feel them? Might a continuous glucose monitor pick up on things you didn’t know about yourself? Could a drop of blood map your future health? Why does your personal baseline matter more than a population average? Could AI decode the massive signaling networks of your body? Does seeing your own data change your behavior? Join Eagleman with Michael Snyder, Stanford professor of genetics and a pioneer in massive personal data, to understand what happens when healthcare moves from a snapshot of your body to a movie.
Why do two people facing the same choice feel different urges? How much effort hides behind resisting a cookie? Why can the brain keep wanting something long after pleasure fades? Can a molecule crank down the volume of your internal radio? Does a biological understanding of behavior reduce responsibility, or does it deepen compassion? And how would your life change if your loudest urge went quiet? Today Eagleman examines free will through the lens of eating disorders, with guest Paige Gordon, an author and former model who spent decades suffering an invisible internal battle.
What happens when we start birthing babies on Mars? Might a Martian human become unable to survive on Earth because of differences in microbes and gravity? How much of your body is shaped by the details of this planet? Will radiation accelerate human evolution on Mars? Could living on Mars eventually create a new species of human? Could Mars change the way humans dream? Would a Martian child find Earth's oceans as strange and awe-inspiring as we find another planet? Could two branches of humanity become too different to recognize each other? Today we’re joined by Scott Solomon, evolutionary biologist and author of the book “Becoming Martian: How Living in Space Will Change Our Bodies and Minds”.
Is AI thinking things it never says aloud? How would we know if a large language model were having a subjective experience? Is there a way to read the 'thoughts' of an LLM? Human brains seem to have a 'global workspace' -- what would it mean if we discovered that AI has something similar? Can you reach inside an LLM to change one of its 'thoughts'? Join Eagleman with Anthropic interpretability researcher Jack Lindsey to talk about what might be going on inside the mind of Claude.
Could there be a better form of government than the one we have now? As we enter an AI-powered world, when might we choose an AI leader? Will your grandchildren ever vote for a human president, who comes with a political party & the weaknesses of a human, or will they vote for a system that has a jaw-dropping capacity to extract patterns from vast rivers of data, simulate millions of possible futures, & govern with a deeper wisdom than a human could naturally possess? Will we all have personal AI agents that know our strongest political opinions, such that we finally achieve (for the first time at scale) a direct democracy rather than a representative one? Join Eagleman as he explores the future of an AI leader (pros & cons) and where he thinks we’re inevitably heading.
What happens when old brain circuitry collides with modern tech? Are we heading into an age of abundance, and can abundance create its own psychological problems? Do we need friction in our lives to become better humans? Could curiosity become the most important survival skill of the twenty-first century? What happens to your biological neural networks when artificial neural networks do your thinking for you? Eagleman sits down with author and researcher Steven Kotler to discuss his new book, We Are As Gods .
A brain computer interface (BCI) is any technology that allows you to connect your 3 pounds of wetware to a computer. But instead of implanting electrodes via neurosurgery, might the next revolution in BCIs come from something very small, like nanoparticles? Would this allow us to spy on millions (or billions) of neurons talking at once -- and could we do so without opening the skull? Will this allow BCI tech to become as common as smartphones? Join Eagleman as he talks with the company Subsense about why the next brain-computer interface might come from thinking small.
Have you ever spent hours with a thought cycling around in your head? What happens when the brain continuously worries, craves, or replays something without finding the exit? Where does the feeling of being “done” come from? Might depression, addiction, OCD, and PTSD all share the same problem? Is mental freedom just the ability to change states? Join Eagleman with neuroscientist and psychiatrist Jonathan Downar to talk about doom loops and how we might break them.
Does your identity and performance change in different situations? What does this have to do with wondering how you’re being judged? What if polarization grows from uncertainty more than hatred? Might social uncertainty be more common than prejudice? Why do strangers become enemies so easily? Can we engineer more trust into society? Today Eagleman sits down with Stanford social psychologist Claude Steele to explore the hidden psychological forces that shape who we become whenever we wonder how other people see us.
What is artificial general intelligence (AGI) and how close are we to getting there? What defines the next step, called artificial superintelligence (ASI), and why might the gap between those two be so dangerous? When machines become smarter than us, what roles are left for humanity? Should we think of AI as software, or as something we’re raising like a child? Will tomorrow’s AI destroy us, ignore us, or protect us? This week Eagleman talks with computer scientist & AI researcher Ben Goertzel.
For all of medical history, we’ve tried to persuade sick cells to behave better. What if instead we just swapped them out? Can we insert new brain cells grown from your own skin cells? And what does any of this have to do with sending one’s own cells into space, or rescuing animals on the very brink of extinction? Today we talk with stem cell biologist Jeanne Loring about the exciting next horizons.
What do honeybee brains have in common with human brains -- and with the AI that beat the world's best Go player? What simple algorithm has been hiding inside brains for 100s of millions of years? When babies throw food from a high chair again and again, are they being mischievous or are they running physics experiments? And what does any of this have to do with whether dopamine is more than a pleasure molecule, or whether there are laws of physics we have yet to discover, or whether large language models are going to get outdated in favor of a new approach? Join Eagleman with computational neuroscientist Read Montague to explore how very old systems in our brains map onto the future of AI.
re you the author of your thoughts or just their witness? Do we simply watch our thoughts like we watch unfolding dream plots? What if the most familiar thing you experience — yourself — isn’t really there? If that’s the case, why does the experience of the self feel so solid that it often takes a lifetime to notice something strange? Why would evolution invent the feeling of a self at all? Join Eagleman with philosopher & neuroscientist Sam Harris as they explore the self, meditation, dreams, movies, and much more.
Could a tiny injury to your brain change your personality? If your friends didn’t know something had happened in your brain, would they just think you're choosing to act strangely? What if the self is nothing but a fragile coalition of neural processes? Join Eagleman today with Masud Husain, a neurologist and neuroscientist at Oxford, to explore fascinating case studies about how changes in the brain lead to changes in the self.
When AI gets the right answer, how do we know it got there the right way? Why do we assume that fluent language means intelligence? What do infants and chatbots have in common? What do AI’s mistakes teach us about our own minds? And what does any of this have to do with Frankenstein’s creature, why some people wear a stop sign on their T-shirt, or smiling monkeys? Join Eagleman today with computer scientist Melanie Mitchell, a professor at the Santa Fe Institute who’s working to bridge AI and cognitive science.
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Observed November 4, 2026.
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