The Biology of Trauma® With Dr. Aimie

You can feel lonely and still not want to be around anyone. What will surprise you is that inflammation itself can create a feeling of disconnection, and loneliness feeds that inflammation back. ➡ Full show notes + resources In this solo episode, Dr. Aimie answers a question from a participant in her practitioner training: why do I feel lonely, but also not want to be around people? She explains the difference between being alone and feeling lonely, why healthy habits did not offset the health cost of loneliness in a study of 277,489 adults, and how stored trauma creates a part that hides and a part that craves connection. She walks through the loop between loneliness and inflammation, and what to do as the holidays come closer, whether you are with family, with friends or on your own: blood sugar, sleep, a containment hug and words of support for the lonely part of you. WHAT YOU'LL LEARN: 00:00 – 03:12 Being Alone vs Feeling Lonely 03:12 – 06:19 Why Healthy Habits Don’t Offset Loneliness 06:19 – 08:56 Stepping Back From Family 08:56 – 11:58 Low Energy, Inflammation and Disconnection 11:58 – 14:39 The Loneliness-Inflammation Loop 14:39 – 18:15 Blood Sugar and Comfort Foods 18:15 – 20:56 Sleep and the Containment Hug 20:56 – 24:23 What to Say to the Lonely Part 24:23 – 26:01 Stress Loneliness or Trauma Loneliness? "I'm not trying to make the loneliness go away. I'm trying to make the loneliness know that it actually isn't all alone." ~ Dr. Aimie Apigian If you feel lonely but too tired to be around people, or you have stepped back from family on your healing journey, this episode is for you. RESOURCES: Get the free Stress or Trauma Guide and learn whether your nervous system has been running a stress response or a trauma response. Get The Biology of Trauma book. Chapter 9 describes the pattern of disconnection. This episode is educational and is not medical advice. Please work with your own qualified healthcare provider for decisions about your care. Grab your copy of The Biology of Trauma

A hard start in life can still be shaping your gut decades later. What will surprise you is that your gut microbes can sense when you are stressed, and they change how they treat your gut wall. ➡ Full show notes + resources Dr. Aimie speaks with Dr. Emeran Mayer, gastroenterologist, neuroscientist and Distinguished Research Professor at UCLA, about how early life stress reaches the gut, the immune system and the brain. He explains increased stress responsiveness, his term for how a difficult birth or childhood becomes biology, and why it does not mean you are doomed. They also talk about why brain fog may start in the gut, the mucus layer that protects the gut wall, and the foods that help it, from diverse fiber to fermented foods. WHAT YOU'LL LEARN: 00:00 – 00:38 Introduction 00:38 – 02:44 The First 1,000 Days 02:44 – 06:31 Early Stress Doesn't Mean You're Doomed 06:31 – 08:44 Hard Births and Stress Responsiveness 08:44 – 10:56 How Early Stress Shows Up in the Gut 10:56 – 14:27 Your Gut Microbes Can Sense Stress 14:27 – 17:28 From Gut to Brain: LPS and Brain Fog 17:28 – 19:17 The Gut's Protective Mucus Layer 19:17 – 21:42 The Interconnected Plate 21:42 – 24:01 Why Food Diversity Matters 24:01 – 26:46 Foods That Protect the Mucus Layer 26:46 – 30:13 Dr. Mayer's Key Message 30:13 – 31:12 Closing Reflection and Stress or Trauma Guide "When a gut microbe is exposed to the stress hormone norepinephrine, it changes its genes and becomes more aggressive toward the bowel wall." ~ Dr. Emeran Mayer If you had a difficult birth or a stressful childhood and have lived with gut symptoms or brain fog for years, this episode is for you. RESOURCES: Get the free Stress or Trauma Guide and learn the physical difference between a stress response and a trauma response in under two minutes. Get The Biology of Trauma book. Chapter 11 explains how early life shapes the filter through which the body meets every later stress. The Mind-Gut Connection by Dr. Emeran Mayer. This episode is educational and is not medical advice. Please work with your own qualified healthcare provider for decisions about your care. Grab your copy of The Biology of Trauma

Emotions held down for decades are still shaping your body. What will surprise you is that the way back can start very small, even with one finger. This is Part 2 of a two-part conversation. Part 1 is here. ➡ Full show notes + resources ➡Trauma Pattern Quiz: https://draimie.co/4jIXc9V Dr. Aimie continues her conversation with Dr. Howard Schubiner, internist, Clinical Professor at Michigan State and an early mentor of hers. He describes what changes in the body when an emotion held down for decades is finally felt and expressed, and why safety and self-compassion make that possible. They talk about why neuroplastic symptoms are reversible, how compassion, curiosity and calm answer the question pain is asking, and where to start when your capacity is very low. WHAT YOU'LL LEARN: 00:00 What changes when buried emotions are finally felt? 01:14 What does it mean that neuroplastic symptoms are reversible? 03:36 How does the nervous system learn its default response? 04:31 What changes in the body when emotions are expressed? 07:15 How do you make it safe to feel buried emotions? 10:37 How can compassion, curiosity and calm change pain? 13:49 Where do you start when capacity is very low? 18:23 How do you train the nervous system with patience? 20:45 Why ask whether your symptoms are neuroplastic? 22:29 How can you see your own patterns of stored emotions? "Sadness turns right into compassion. Anger gets expressed, and you let it go." ~ Dr. Howard Schubiner If you have held your emotions down for years and wonder whether it is safe to feel them, this episode is for you. RESOURCES: Take the free 2-Minute Assessment for Stored Trauma and see which patterns of stored trauma are most active for you. Get The Biology of Trauma book. Chapter 3 explains capacity and the critical line of overwhelm. Unlearn Your Pain by Dr. Howard Schubiner. The Foundational Journey , a clear path for stabilizing your internal state and nervous system. This episode is educational and is not medical advice. Please work with your own qualified healthcare provider for decisions about your care. Grab your copy of The Biology of Trauma

➡ Full show notes + resources ➡ Trauma Pattern quiz : Pain that no test has fully explained is still real pain. What will surprise you is that the brain decides whether to turn on pain, and it treats emotional danger from childhood or from an unjust world as danger. This is Part 1 of a two-part conversation Dr. Aimie welcomes back Dr. Howard Schubiner, internist, Clinical Professor at Michigan State and author of Unlearn Your Pain . He describes how a child who learned to keep the peace grows into an adult whose brain still reacts to everyday stress as danger, and why he sees racism and injustice as sources of pain. They talk about why chronic pain, fatigue and POTS keep rising while the body has not changed, why neuroplastic symptoms are real and reversible, and how someone with rheumatoid arthritis can carry both structural and neuroplastic pain. Trauma Pattern quiz : WHAT YOU’LL LEARN: 00:00 Why would the brain create pain? 02:02 Can emotional pain cause physical pain? 04:23 How does a childhood without safety become pain later? 07:32 Can racism and injustice cause chronic pain? 10:08 Why are chronic pain, fatigue and POTS becoming more common? 14:37 Can rheumatoid arthritis pain be neuroplastic? 18:27 How can the nervous system learn it is safe? “Not all pain is due to injury. It’s our job to sort it out because emotional pain can cause physical pain, and that’s a fact. And that’s how we’re wired.” ~ Dr. Howard Schubiner If you live with pain that no test has fully explained, this episode is for you. RESOURCES: Take the free 2-Minute Assessment for Stored Trauma and see which patterns of stored trauma are most active for you. Get The Biology of Trauma book. Unlearn Your Pain by Dr. Howard Schubiner. The Foundational Journey , a clear path for stabilizing your internal state and nervous system. This episode is educational and is not medical advice. Please work with your own qualified healthcare provider for decisions about your care. ➡ Full show notes + resources Grab your copy of The Biology of Trauma

➡ Full show notes + resources You react to everything. You want to find the cause and get rid of it. What will surprise you is that the most common place people start, binders, chelation or a mold detox, may be the very thing that makes a reactive body worse. This is Part 2 of a two-part conversation. Part 1 is here: Apple · Spotify · show notes . Dr. Aimie and Dr. Bruce Hoffman talk about where to start when the body reacts to everything. Dr. Hoffman shares the order he used for 30 years with his most complex patients: safety first, then daylight and natural rhythms, self-regulation, POTS, and then calming the mast cells, with binders, chelation and mold treatment much later. They also cover which medications calm mast cells, why supplements alone rarely do, how to tell a Herxheimer reaction from a mast cell reaction, and why mast cell labs so often come back normal. WHAT YOU'LL LEARN: 00:00 Where do you start when your body reacts to everything? 02:57 Why does safety come first for highly reactive patients? 04:03 What are the health cycle principles? 06:48 What order did Dr. Hoffman use with his most complex patients? 08:11 How do you stabilize mast cells beyond histamine? 10:50 Can supplements stabilize mast cells? 12:45 Why not start with binders or antibiotics? 16:19 Herxheimer or mast cell reaction: how can you tell? 19:29 What is a therapeutic trial? 21:11 Why wait 3 to 6 months before chelation? "I never approached the toxic load until I've got them stabilized in the health cycle principles, self-regulation, POTS, and mast cells." — Dr. Bruce Hoffman If you have tried detox after detox and your body only gets more reactive, this episode is for you. RESOURCES: Get the free Companion Guide to Mast Cell Reactivity . Every term and medication from this conversation explained in plain words, in the order it comes up. [Swap for the tracked Apple show notes link, campaign ep198-stabilize-mast-cells, needs a Lead Magnet Inventory row] Get The Biology of Trauma book . Chapter 12 lays out the biology lens that follows this same sequence. [VERIFY chapter] Dr. Bruce Hoffman’s website and his Substack, The New Medical Curriculum . The Foundational Journey , a clear path for stabilizing your internal state and nervous system. This episode is educational and is not medical advice. Please work with your own qualified healthcare provider for decisions about your care. ➡ Full show notes + resources Grab your copy of The Biology of Trauma

Full show notes + resources [ COMPANION GUIDE NAME ]: Every term from this conversation explained in plain words, in the order it comes up. First it was one food. Now it is smells, supplements, heat and stress, and the list keeps growing. What will surprise you is that mast cells respond to your total load, and a sensitized system can react to the thought of a trigger alone. This is Part 1 of a two-part conversation. [Part 2 is here: EP 198 LINK] Dr. Aimie sits down with Dr. Bruce Hoffman, who spent 30 years treating highly reactive, complex chronically ill patients. He explains why stress, from early trauma or daily life, is the largest trigger of mast cell activation he sees, and why the trigger list grows as toxins, processed food and indoor living add to the load. Dr. Aimie breaks down the cell danger response, the footprint childhood trauma leaves as oxidative damage, and the two-way loop that keeps mast cells and the nervous system setting each other off. WHAT YOU'LL LEARN: 00:00 Why are so many people reacting to everything? 02:52 How does early childhood trauma load the mast cells? 05:39 What is the cell danger response? 09:16 Why does childhood trauma show up as oxidative damage today? 12:32 Why does the trigger list keep getting longer? 14:39 What sets the threshold for mast cell activation? 17:58 Can mast cells react to a threat that is only predicted? 22:19 How do mast cells keep the nervous system on alert? 24:10 Why do people react to the supplements meant to help them? 27:21 Why does a roadmap create safety? "You don't even have to have the threat. You can just think about it and your mast cells degranulate." — Dr. Bruce Hoffman If you react to more foods, smells and supplements every year and no one can tell you why, this episode is for you. RESOURCES: Get the free [ COMPANION GUIDE NAME ]. Every term from this conversation explained in plain words, in the order it comes up Get The Biology of Trauma book . Chapter 4 covers the cell danger response Never Bet Against Occam by Dr. Lawrence Afrin Grab your copy of The Biology of Trauma

➡ Full show notes + resources: 2 Min Assessment: In this solo episode, Dr. Aimie explains what dysregulation actually is and why it never exists on its own. She walks through the patterns of stored trauma that feed it, and the four questions you can use to tell whether your nervous system is healing. She also shares why children's nervous systems change faster than adults', what a patient in the ICU taught her about changing slowly, and why biology is the most neglected piece of nervous system repair. WHAT YOU'LL LEARN 00:00 Intro: How Long Does Healing Take? 02:06 How the Nervous System Responds to Change 03:52 Overreacting, Underreacting, and Responding 06:26 Why Dysregulation Can't Create Health 08:14 The Five Steps of the Body's Trauma Response 10:57 Stuck in the Body Trauma Loop 12:35 Dissociation and Immobilization 15:03 Energy Conservation and Depletion 16:58 Why Dysregulation Never Happens Alone 18:49 The Fifth Pattern: When Trauma Becomes Disease 21:48 The Time Factor: Why Healing Takes Longer for Adults 25:53 Why Change Must Be Paced: A Lesson from the ICU 27:37 The Biology Piece: How to Accelerate Healing 29:35 Free Assessment and Closing "The longer that the nervous system has lived this way, the slower that change has to go in order for the nervous system to integrate that change over time." — Dr. Aimie Apigian If you have been working on your healing for years and cannot tell whether any of it is working, this episode is for you. RESOURCES: Take the free 2-Minute Assessment for Stored Trauma. Get a picture of your patterns now, so you have something to measure your healing against. Get The Biology of Trauma book . The fifth pattern, disease, is in Chapter 10, When Trauma Becomes Disease. This episode is educational and is not medical advice. Please work with your own qualified healthcare provider for decisions about your care. ➡ Full show notes + resources: Grab your copy of The Biology of Trauma

Your labs keep coming back acceptable. Your symptoms keep getting harder to hold. And you have probably landed on one of two conclusions: either something is wrong with you that nobody has found yet, or something is wrong with how you are handling it. I want to offer a third. Full show notes Three things change at the same time in this decade, and each one is invisible on its own. Your immune baseline was set decades before perimenopause. Estrogen, which your immune system has been reading as an instruction every day for years, stops declining in a straight line and starts swinging. And cortisol, which is one of the most powerful anti-inflammatory signals your body makes, stops being received even while your body is producing more of it. That third one is why a normal lab result can be a false negative. The all clear is being sent. It is not landing. In this episode I walk through all three, and I translate the research into language you can use with your own provider. I also tell you why I stopped calculating ACE scores, what a hazard ratio actually means when you read one about your own health, and what has to be stabilized before anything else will hold. Perimenopause does not create the autoimmunity. It does not create the pattern either. It removes the margin that had been holding that pattern quietly, which is why it feels like it arrived out of nowhere. In this episode: Why a cortisol test can read normal while inflammation gets worse The four immune control points estrogen sits at Why unpredictable estrogen costs more than declining estrogen What "seventy percent increased risk" really means Why I stopped calculating ACE scores What has to come first, and why most people start at the wrong end Resources: Take the free 2-Minute Assessment for Stored Trauma: https://biologyoftrauma.scoreapp.com/?utm_source=podcast&utm_medium=podcast_audio&utm_campaign=ep195-autoimmunity-perimenopause&utm_content=show-notes The Biology of Trauma by Dr. Aimie Apigian: https://www.amazon.com/dp/1637746237?tag=draimie-20 Full show notes: https://www.biologyoftrauma.com/post/episode-195-why-autoimmune-symptoms-get-worse-in-perimenopause Full show notes Grab your copy of The Biology of Trauma

I do not ask about your past. I do not get out the checklist of adverse childhood experiences. I am not calculating your ACE score. And I know how strange that sounds coming from a physician who works with stored trauma. Full show notes What I look at is the impact of your past on your today, because that is where it is still leaving its footprint. In this episode I walk you through the assessment I teach practitioners, so you can run it on yourself. Three domains, one repeating pattern, and the equation that decides whether a stressor stays a stress or tips you into overwhelm. Then I take you to the part that surprises people most. Trauma work runs on energy. If your body does not have the capacity, the work cannot integrate no matter how willing you are. Which means the most useful place to start is sometimes sleep, or brain inflammation, rather than the trauma itself. That is still trauma work. I also tell you about the pattern I carried for thirty years, and how it changed without me ever going looking for the reason. In this episode: Why the word trauma gets in the way of finding trauma The three domains I ask about, and the one pattern that runs through all of them Your capacity against your stress load, and what happens when capacity is small Where stress ends and overwhelm begins Why perimenopause costs more capacity than most women expect The nervous system dashboard, and the three things that feed it Why I sometimes tell someone not to do the trauma work yet How to find your biggest block without handing yourself the whole list Find your pattern: Take the free 2-Minute Assessment for Stored Trauma The book: The Biology of Trauma by Dr. Aimie Apigian Full show notes This podcast is educational and is not medical advice. Consult your own physician about your health. Grab your copy of The Biology of Trauma

Your labs confirmed the autoimmune diagnosis. The hardest symptom turned out to be the one nobody prepared you for. Dr. Aimie goes solo on depression and autoimmunity, and which one actually comes first. The answer is less orderly than the one most people are given, and it changes what to do about it. ➡️ Full show notes and research: CLICK HERE Most people are told depression is a reasonable response to being ill. Dr. Aimie interrupts that conclusion with what the research shows: each condition carries close to double the risk of the other, depression turns up in the two years before a diagnosis is made, and roughly a quarter of the link between early adversity and autoimmune disease appears to travel through mental health on the way. She also walks through why this depression rarely feels like sadness, and why the medication may have underperformed. She was on two of them herself, and the hardest part was not the depression. WHAT YOU'LL LEARN: 0:00 The hardest symptom of an autoimmune diagnosis 02:41 — Why is depression treated as the reasonable response to a diagnosis? 04:49 — What does double the risk actually mean for you? 07:58 — What is a dose-response pattern and why does it matter? 09:45 — Where does the childhood adversity evidence stop? 12:19 — What does it mean that depression mediates part of the link? 13:54 — What happens when your cells stop responding to cortisol? 15:55 — Why does this feel like the flu rather than sadness? 20:48 — Why has working on your thoughts not moved it? 22:55 — Why do antidepressants underperform here? 24:54 — What does the infliximab trial actually prove? 28:48 — Where do you start when both are running? "Depression is part of the road from I was healthy to I now have an autoimmune diagnosis." — Dr. Aimie Apigian If the antidepressant did not do much and you quietly concluded something was wrong with you, this episode is for you. RESOURCES: Take the FREE 2-Minute Assessment for Discovering Your Pattern of Stored Trauma : You cannot change a pattern you cannot see. Find your primary pattern of responding when life becomes too much, then see how the other four show up. Get The Biology of Trauma : Disease is one of the five patterns of stored trauma. Nothing in this episode is a recommendation to change or stop a medication. Talk to the prescriber who knows your history. This episode is educational and is not medical advice. Please work with your own qualified healthcare provider for decisions about your care. Grab your copy of The Biology of Trauma

You have been doing the work. The therapy, the somatic practices, the self-care. And your body still will not come online. You have also been doing the gut protocol. Months of it. And the exhaustion has not lifted. Here is what almost nobody tells you. The thyroid governs gut motility. When it runs low and slow, the bloating and the constipation you have been treating from the gut end may have been downstream of the thyroid the whole time. So you can do everything right, in the right order, and still be working the wrong end of the problem. This is Part 2 with Dr. Amie Hornaman, known as the Thyroid Fixer. She was misdiagnosed six different times in her twenties before anyone found it. In this episode she gets practical about selenium, about which system to start with, and about why she thinks adrenal fatigue is overdiagnosed. She also gives a number for how long before your energy and stress resilience actually shift, with the caveat that belongs beside it. WHAT YOU'LL LEARN: Which to treat first when your gut and thyroid are both struggling How a slow thyroid produces constipation, bloating and SIBO The foundational nutrients she starts everyone on, and why selenium leads Why one morning cortisol reading cannot tell you what you think it does How long before energy, mood and stress resilience begin to move The full show notes have the research behind the SIBO connection, every quote from the episode, the chapter list, and the optimal lab ranges to ask about. Read the full show notes: https://www.biologyoftrauma.com/post/gut-or-thyroid-first-when-you-are-in-chronic-freeze RESOURCES: Get the Stress or Trauma Guide Part 1 of this conversation By listening to this podcast, you agree not to use it as medical, psychological, or mental health advice to treat any condition in yourself or others. This podcast is for informational and educational purposes only. Always consult your own qualified health provider. Grab your copy of The Biology of Trauma

You have been doing the work. You understand your patterns. And you are still waking up unable to face the day. When the body decides survival is the priority, it stops converting thyroid hormone into the form your cells can use. It produces an inactive version instead, called reverse T3, and that version blocks the active hormone at the cell door. The result is a body running low and slow. It is the same physiology I call chronic functional freeze. Dr. Amie Hornaman ranks reverse T3 as the single most important thyroid marker, ahead of free T3, and it is a marker almost nobody orders. She also holds that stress and trauma on their own can raise it. This is Part 1 of a two part conversation. ➡️ Full show notes, research and timestamps: https://www.biologyoftrauma.com/post/can-a-thyroid-problem-keep-me-in-chronic-freeze WHAT YOU'LL LEARN: Why a normal TSH does not settle the question of whether your thyroid is involved What reverse T3 is, and why Dr. Hornaman ranks it above free T3 How stress and trauma can shift thyroid function directly Why the hibernation state and chronic functional freeze are the same physiology What happens to the thyroid in the year after an injury or accident Why you cannot think your way out of a decision the body made below thought RESOURCES: Take the free 2-Minute Assessment for Stored Trauma: https://biologyoftrauma.com/quiz Stress or Trauma Guide The Biology of Trauma : https://www.biologyoftrauma.com/book The Thyroid Fix by Dr. Amie Hornaman Part 2 releases August 20, 2026. Grab your copy of The Biology of Trauma

Most trauma has a place you can avoid. Medical trauma lives inside your body, so there is nowhere to go. Dr. Aimie sits down with Dr. James Jackson for the second half of their conversation on medical trauma. What will surprise you is how much recovery is available while the symptoms are still present. This is Part 2 of a two part conversation. Part 1 is here. ➡ Full show notes + resources: https://bit.ly/BOT190 Dr. Jackson works with people recovering after critical illness, and he is direct about something most clinicians avoid saying. Patients have been taught that recovery means every symptom is erased. That standard fails most bodies. He offers a different measure, along with the markers that actually move. Dr. Aimie also shares why she left general surgery residency after four years, and the one question she started asking her patients that changed everything about how she practiced. WHAT YOU'LL LEARN: 02:55 — Why do you carry the source of a medical trauma with you? 05:35 — What is acceptance and commitment therapy? 06:37 — How can you be fine right now? 07:09 — Why did Dr. Aimie leave general surgery residency? 08:17 — What happens when you ask a patient what their diagnosis means to them? 11:40 — Why should no one else decide what counts as a big trauma? 13:33 — Why is overselling recovery a problem? 14:46 — What does a rich recovery actually look like? 15:32 — What are the objective markers that recovery is happening? 17:02 — How should we talk about post-traumatic growth? 20:22 — Why can no one recover from medical trauma alone? "If the trauma happened in your body, you're carrying that around. You're carrying it around, and you can't avoid it. It's always there." — Dr. James Jackson If you have quietly decided you are not recovering because something still hurts, this episode is for you. RESOURCES: Take the free 2-Minute Assessment for Discovering Your Pattern of Stored Trauma . You cannot change a pattern you cannot see. Find your primary pattern of responding when life becomes too much, then see how the other four show up. Get The Biology of Trauma . Avoidance and the pattern of disconnection are on page 117, chapter nine, The Patterns of Pain: Recognizing Stored Trauma in the Body. Reclaiming Your Life from Medical Trauma by Dr. James C. Jackson, PsyD. This episode is educational and is not medical advice. Please work with your own qualified healthcare provider for decisions about your care. Grab your copy of The Biology of Trauma

A hospital saved your life, and now you plan your route so you do not drive past it. That has a name, and the name is medical trauma. Medical trauma is a trauma response that comes from a medical experience. It can follow an ICU stay, a hard surgery, or an emergency C-section. Post-intensive care syndrome, or PICS, describes new or worsened problems in thinking, mood, and physical function after critical illness. Full show notes: https://www.biologyoftrauma.com/post/why-do-i-avoid-the-doctor-now-medical-trauma-and-post-intensive-care-syndrome-with-dr-james-jacks Dr. James Jackson of Vanderbilt co-founded one of the first clinics in the country for survivors of critical illness. He sat on front porches across the South asking people what their life was like after the ICU, and he heard the same story hundreds of times. In this Part 1 conversation with Dr. Aimie, he names the one sign he watches for above all others, why so many doctors have never heard of PICS, and how long recovery actually takes. This is Part 1 of two. Part 2 is here: Take the free 2-minute assessment for stored trauma at biologyoftrauma.com/quiz . Find your primary pattern of responding when life becomes too much. You cannot change a pattern you cannot see. The Biology of Trauma book: biologyoftrauma.com/book Reclaiming Your Life from Medical Trauma, by Dr. James C. Jackson, PsyD. Full show notes: https://www.biologyoftrauma.com/post/why-do-i-avoid-the-doctor-now-medical-trauma-and-post-intensive-care-syndrome-with-dr-james-jacks This content is educational and is not medical advice. It is not intended to diagnose or treat any condition. Always consult your own qualified health provider. Grab your copy of The Biology of Trauma

A new mom was losing weight without trying. Her heart raced. Waves of panic arrived without warning. Her doctor congratulated her on the weight and offered her something for the anxiety. Her anxiety had been doing its job the whole time. It was a message from her thyroid. In Part 2, Dr. Aimie and Dr. Nicole Cain, author of Panic Proof, walk through the last six of the nine body systems that can produce anxiety. Nervous system, endocrine, immune system, depressive, anger, and trauma anxiety. Each one leaves a different signature, and each one asks for something different. You will hear why anger rises as you come out of chronic functional freeze, and how trauma work shifted one woman's biology down to what showed up on objective testing. In This Episode You'll Learn: 01:00 — What is nervous system anxiety? 02:53 — Which herb supports a nervous system worn down by stress? 03:42 — What blood work should I ask for? 04:37 — How did Charlotte's anxiety turn out to be her thyroid? 07:17 — What is immune system anxiety? 08:35 — Why does an antihistamine sometimes settle anxiety? 09:07 — How does inflammation in the brain create anxiety? 11:33 — Can my gums be affecting my anxiety? 13:01 — What is depressive anxiety, and what can an SSRI set off? 17:07 — What is anger anxiety, and how do I cool it down? 18:57 — Why am I angrier as I come out of freeze? 20:36 — Can trauma work change a condition like PCOS? Resources/Guides: Get the free guide, Is It Stress or Trauma? Discover your primary pattern of responding when life becomes too much. Read Panic Proof by Dr. Nicole Cain. All nine types, with quizzes and checklists. The Biology of Trauma book. The biology underneath these anxiety types. Part 1 of this conversation covers cardiac, gut, and thought anxiety . This episode includes a description of a child being physically hurt by a parent, and discusses SSRIs, benzodiazepines, and herbs. This podcast is for educational purposes and is not medical advice. Always consult your own qualified health provider before changing any medication, supplement, or herb. ➡️ Full show notes with links and resources: Grab your copy of The Biology of Trauma

You feel anxious. Nothing has happened. Nothing is wrong on paper. Dr. Aimie learned in the emergency room that anxiety is never one thing. Someone would come in and say the word, and her job was to work out why. It could be a hard week. It could be a heart attack. Same word, two entirely different bodies. She still runs that checklist on herself. Then she read Dr. Nicole Cain's book Panic Proof and found the same approach mapped into nine types, each one named for the body system driving it. In this Part 1 conversation, they cover the first three. Cardiac, gut, and thought anxiety. You will learn how to tell fear from anxiety from panic, why the first place you feel it is your best clue, and why the same word describes both high energy activation and shutdown. This is Part 1 of two. WHAT YOU'LL LEARN: 03:15 Why anxiety gets treated as one condition 06:33 Fear, anxiety, and panic as three different states 08:07 The green, yellow, and red zones 09:31 How your body measures how much danger you are in 11:08 Your canary, and why the first signal matters 12:25 High energy anxiety or shutdown 13:27 Flop, fawn, fracture, and perimenopause 15:24 The therapeutic order 17:09 Cardiac anxiety, and when to see a cardiologist 19:28 Gut anxiety and the gut-brain axis 21:11 What a food and mood journal revealed 22:34 Thought anxiety and looping thoughts 25:07 Parts work, and the moment it landed for Miguel RESOURCES: Get the free guide, Is It Stress or Trauma? For working out whether what you carry is ordinary stress, or something past that line. Get The Biology of Trauma book . Read Chapter 3, on our critical line and our capacity. It covers how the body reads danger. Panic Proof by Dr. Nicole Cain Dr. Nicole Cain's website Full show notes This episode includes a personal disclosure about thoughts of suicide connected to a food reaction. Content here is educational and is not medical advice. Grab your copy of The Biology of Trauma

You know the thing that would help. You have known for a while. You still have not done it. Dr. Aimie recognized herself in the research on learned helplessness. For a long stretch of her life she expected everything to be hard, expected to fail, and quietly stopped trying without ever deciding to. It is not laziness. It is a body that learned effort did not matter and powered the effort down. In this Part 2 conversation, recorded in Josh Trent's Austin studio, they talk about what separates resting from escaping, why the drive built on your own wound eventually stops working, and how a little safety is enough to take the next step. This is Part 2 of two. Part 1 is here: https://www.biologyoftrauma.com/post/why-do-we-escape-instead-of-rest-josh-trent-on-emotional-epigenetics WHAT YOU'LL LEARN: 02:04 How to tell resting from escaping 04:25 The three questions behind your purpose 06:48 Why the fuel of your own wound stops working 07:58 Grieving the old identity 10:05 Why showing up takes borrowed energy 13:24 Conditioned happiness and the opposite he found 17:18 The Seabiscuit story and learned helplessness 21:45 Recognizing the pattern in someone else 26:49 What most people misunderstand about a leader 30:20 Freedom fuels flow, fear fuels force 31:27 Why curiosity needs safety first RESOURCES: Take the free 2-Minute Assessment for Stored Trauma . Discover your primary pattern of responding when life becomes too much, then see how the other four show up. Get The Biology of Trauma book . Read Chapter 13, on why the body will not rest until it feels safe, and how to start building that safety. Josh Trent hosts the Wellness + Wisdom Podcast Full show notes: https://www.biologyoftrauma.com/post/why-is-not-trying-a-survival-response-not-a-weakness-with-josh-trent-part-2 Grab your copy of The Biology of Trauma

You finally have an evening with nothing in it. Twenty minutes later you are on your phone. Josh Trent spent most of his life in a body that did not know how to rest. A clench in his stomach. A breath that stayed high in his chest. His first memory is of being a boy watching the adults around him be angry, unable to change it and unable to leave. The bracing stayed for thirty years. Dr. Aimie and Josh talk about why stillness can feel unsafe, what separates real rest from escape, and why so many practitioners hold grief in a diaphragm that will not drop. This is Part 1 of two. Part 2 releases July 30. WHAT YOU'LL LEARN: 01:22 How one question from childhood shaped an entire life 05:11 What happens when you know something is missing 09:24 How patterns get passed down through a family 13:49 The moment feeling became the way back in 17:12 Feeling an emotion in your body for the first time 18:38 Why practitioners carry grief in their bodies 19:31 What worries a wellness leader most about his own industry 23:57 Why social media makes it harder to feel 26:20 The difference between rest and escape RESOURCES: Take the free 2-minute assessment for stored trauma . Find your primary pattern of responding when life becomes too much, then see how the other four show up. Is it stress or is it trauma? The guide that walks through the difference. Josh Trent hosts the Wellness + Wisdom Podcast. Full show notes: https://www.biologyoftrauma.com/post/why-do-we-escape-instead-of-rest-josh-trent-on-emotional-epigenetics Grab your copy of The Biology of Trauma

Why do I crash every time I finally slow down? Maybe you feel fine all week, then crash on the weekend. Maybe an open Saturday fills you with a quiet dread. So you fill it. An early bike ride. A full list. Anything to keep moving. Many people call this high-functioning burnout. It has a name, and it has a cause. ➡️ Full show notes: https://www.biologyoftrauma.com/post/episode-184-why-you-crash-when-you-slow-down-the-pattern-of-depletion WHAT YOU'LL LEARN: 01:34 — Why do I crash every time I finally slow down? 04:03 — What is the pattern of disconnection, and why do I feel numb or distant? 04:33 — What is the pattern of disruption, and why do I feel stuck and unable to move forward? 05:03 — What is the pattern of depletion, and why do I feel like I'm running on empty? 05:15 — What is the pattern of dysregulation, and why does my nervous system overreact or under-react? 05: 32 — What is the pattern of disease, and how does stored trauma become physical symptoms? 06:30 — Why is the pattern of depletion the one that hides? 08:52 — Why does the crash come with the rest, if the rest did not cause it? 11:22 — How are stress and burnout different to my biology? 12:53 — What is capacity, and why does low capacity turn stress into overwhelm? 16:33 — What does it mean to live at two speeds, fast and stopped? 18:35 — How does depletion show up in my biology, from magnesium to ferritin? Resources/Guides: Stress or Trauma Guide — a free guide to tell a stress response from a trauma response, and see the sequence your nervous system needs next. ➡️ Full show notes with links and resources: https://www.biologyoftrauma.com/post/episode-184-why-you-crash-when-you-slow-down-the-pattern-of-depletion Grab your copy of The Biology of Trauma

Most of us were told to grieve, to rest, to be present. Nobody taught us the skill. In Part 2, Dr. Aimie and neuroscientist Dr. David Rabin get into heart rate variability and resilience, why anxiety masks itself as focus, and why grieving is a skill your body has to learn. Feeling safe enough to feel is where the work begins. ➡️ Full show notes: https://www.biologyoftrauma.com/post/why-grieving-is-a-skill-what-hrv-reveals-about-resilience-david-rabin 01:03 — Why is heart rate variability the key marker for resilience? 03:08 — What is intention, and what is it in the nervous system? 04:08 — Where does intention fit if you have lived in hypervigilance? 08:18 — What practices in therapy get in the way of healing? 11:28 — How do you apply these principles in a full, busy life? 16:33 — How do you grieve a loss, and why is grieving a skill? Listen to Part 1 here . Resources/Guides: Get the "Is It Stress or Trauma" Guide . Know whether what your body is carrying is stress or something deeper. ➡️ Full show notes with links and resources: https://www.biologyoftrauma.com/post/why-grieving-is-a-skill-what-hrv-reveals-about-resilience-david-rabin Grab your copy of The Biology of Trauma