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Published by Dr Swapnil Pawar & Dr Madhuri Anupindi
This podcast is about Intensive care pharmacology and physiology. This is created to prepare intensive care trainees for their primary CICM exams. However, it will be of benefit to anyone who works in intensive care and keen to acquire new knowledge or want to refresh their memory.
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In this episode, we discuss viscoelastic testing in ICU using ROTEM. We cover the main assays (EXTEM, INTEM, FIBTEM, APTEM and HEPTEM), the key parameters (CT, CFT, A10, MCF and ML), and the expected changes and underlying mechanisms in platelet dysfunction, therapeutic heparin use and hyperfibrinolysis. Read the full episode notes on Substack: https://critcareedu.substack.com/p/rotem-platelet-dysfunction-heparin
In this episode, we discuss the definition of morbid obesity and the cardiovascular changes associated with it, including effects on preload, left and right heart function, cardiac output, pulmonary and systemic circulation, coronary circulation, and cardiac conduction.
In this episode, we discuss the differences between EVD and intrapreanchymal ICP monotors.
In this episode, we discuss the pharmacology of Meropenem.
In this episode, we discuss the classification of anticonvulsants and the pharmacology of gabapentin.
In this episode, we discuss the anatomy for the lumbar puncture and compare the differences between adult and paediatric populations.
In this episode, we discuss underlying principles of various temperature measurement methods.
In this episode, we discuss the anatomy of sympathetic nervous system w.r.t origin, fibre type, receptors and neurotransmitters.
In this episode, we compare and contrast the pharmacological profiles of Metoprolol and verapamil.
In this episode, we cover the production, metabolism and the role played by lactate in the body.
In this episode, we discuss the concept of Work of breathing and lung efficiency.
In this episode, we discuss the procedural anatomy of the femoral vein including surface
In this episode, we discuss the process of fibrinolysis in relation to coagulation cascade and the pharmacology of Alteplase.
In this episdoe, we compare and contrast fentanyl and remifentanyl.
in this episode, we discuss the role of various receptors and describe the terms - partial agonist, antagonist, and inverse agonists.
In this episode, we discuss the concept of venous admixture and the effect of supplemental oxygen on it in adults.
In this episode, we discuss the consequences of sudden and sustained afterload increase on the Left ventricle.
In this episode, we discuss the differences between two diuretic medications - Furosemide and Acetazolamide.
In this episode, we discuss various opioid receptors, their characteristics, distribution and activation process.
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Observed November 4, 2026.
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