JAMAevidence Users' Guides to the Medical Literature

Toshi A Furukawa, MD, PhD, Kyoto University, Graduate School of Medicine, School of Public Health, discusses Understanding Bias and Random Error in Medical Research with Gordon H. Guyatt, MD, MSc, McMaster University. Related Content: CONSORT 2025 Statement Using Instrumental Variables to Address Bias From Unobserved Confounders

Thomas Agoritsas, MD, PhD, Geneva University Hospitals, Switzerland discusses Users' Guides to the Medical Literature about patient management recommendations with author Gordon H. Guyatt, MD, MSc, McMaster University. Related Content: How to Interpret and Use a Clinical Practice Guideline or Recommendation Platelet Transfusion Caring for Patients With Acute Respiratory Distress Syndrome

Mark C. Wilson, MD, MPH, University of Iowa, Carver College of Medicine discusses Evidence-Based Practitioners and Evidence-Based Care with Gordon H. Guyatt, MD, MSc, McMaster University. Related Content:

Mark C. Wilson MD, MPH, University of Iowa, discusses Teachers' Guides to the Users' Guides with Gordon H. Guyatt, MD, MSc, McMaster University. Related Content: Evidence vs Consensus in Clinical Practice Guidelines How to Interpret and Use a Clinical Practice Guideline or Recommendation

Gordon H. Guyatt, MD, MSc, discusses Assessing the Strength of Recommendations: The GRADE Approach with Per Olav Vandvik, MD, PhD. Related Content: How to Interpret and Use a Clinical Practice Guideline or Recommendation

Host Gordon Guyatt, MD, MSc, discusses Understanding and Applying the Results of a Systematic Review with M. Hassan Murad, MD, MPH. Related Content: How to Read a Systematic Review and Meta-analysis and Apply the Results to Patient Care Acute Treatments for Episodic Migraine in Adults

Gordon H. Guyatt, MD, MSc, discusses Fixed-Effects and Random-Effects Models with M. Hassan Murad, MD. Related Content: Random-Effects Meta-analysis

Gordon H. Guyatt, MD, MSc, discusses Adjusted Analyses in Studies Addressing Therapy and Harm with Thomas Agoritsas, MD, PhD. Related Content: Adjusted Analyses in Studies Addressing Therapy and Harm

Gordon Guyatt, MD, MSc, discusses Spectrum Bias with Reem A. Mustafa. MD, MPH, PhD.

Gordon Guyatt, MD, MSc, discusses Discrimination and Calibration of Clinical Prediction Models with Ana Carolina Alba, MD, PhD. Related Content: Discrimination and Calibration of Clinical Prediction Models With Dr Alba Read Transcript

Host Robert M. Golub, MD, discusses How to Interpret and Use a Clinical Practice Guideline or Recommendation with Gordon H. Guyatt, MD, MSc, and Romina Brignardello-Petersen, DDS, MSc, PhD.

Gordon Guyatt, MD, discusses Measuring Agreement Beyond Chance with Thomas McGinn, MD, MPH. Related Content: Does This Patient Have Infectious Mononucleosis? The Rational Clinical Examination Systematic Review

Gordon H. Guyatt, MD, MSc, discusses Correlation and Regression with Roman Jaeschke, MD, MSc.

Gordon Guyatt, MD, discusses economic analysis with Paul Moayyedi, PhD

Gordon Guyatt, MD, discusses Misleading Presentations of Clinical Trial Results with Victor Montori, MD Related Content: Misleading Presentations of Clinical Trial Results with Dr Victor Montori When Can Intermediate Outcomes Be Used in Clinical Trials? When Guidelines Recommend Shared Decision-making

Anne M. Holbrook, MD and Gordon Guyatt, MD, discuss Surrogate Outcomes from the JAMA Users' Guides to the Medical Literature Related Content: When Can Intermediate Outcomes Be Used as Surrogate Outcomes? FDA Acceptance of Surrogate End Points for Cancer Drug Approval: 1992-2019 What Constitutes a Valid Surrogate End Point in Cancer Clinical Trials?

Interview with Yun Liu, author of How to Read Articles That Use Machine Learning: Users' Guides to the Medical Literature

JAMA Deputy Editor Edward Livingston, MD, discusses "Cluster Randomized Trials: Evaluating Treatments Applied to Groups" With William J. Meurer, MD, MS

Ed Livingston, MD, FACS, AGAF, discusses Dose-Finding Trials: Optimizing Phase 2 Data in the Drug Development Process with Kert Viele, PhD

Ed Livingston, MD, FACS, AGAF, discusses Noninferiority Trials: Is a New Treatment Almost as Effective as Another? with Amy Kaji, MD, PhD