Join Dr. Joel Kahn, the internationally recognized heart doctor, as he brings his unique blend of Eastern and Western medicine to Heart Doc VIP, the podcast that empowers you to take charge of your health. With a focus on the wellness of mind, body, and spirit, Dr. Kahn delves into the latest research and interviews leading experts in the health and wellness space, including Health Heroes who share their inspiring journeys to wellness. Each episode of Heart Doc VIP provides listeners with practical advice and tools to help them live their best lives. Dr. Kahn doesn't shy away from controversial topics and is not afraid to take on the giants and expose lies, follies, and confusion in the health industry. With his extensive knowledge and experience, he guides listeners through the maze of conflicting information to help them make informed decisions about their health. So if you're ready to feel better, look better, and live better, join Dr. Joel Kahn on Heart Doc VIP, the podcast that's changing the way we think about health and wellness.
This week, Dr. Kahn discusses new data from the amazing Valter Longo, PhD, and his colleagues regarding optimizing diet for both longevity and strong muscles. In a new publication, Dr. Longo used mouse models to show that animals fed a Longevity Diet, as described in his book, lived longer. However, when moderate amounts of methionine, an amino acid, were included in the diet, frailty was avoided. He then analyzed a dataset of 200,000 health professionals in the United States and found that those consuming the highest amounts of animal protein had double the risk of type 2 diabetes, as well as higher rates of obesity and hypertension, compared with those consuming more plant protein. You can learn more about Dr. Longo's L-Protein powder (with methionine) at prolonlife.com/drkahn . Other topics include PCOS and heart disease, aortic dissection, artificial sweeteners and memory loss, optimal medical treatment for high cholesterol, GLP-1 agonist use and hair loss, TMAO and the risk of atrial fibrillation, statins and better cognitive function in women, and how plant mitochondria may improve our own cellular function. Amazing. Thanks to the Fresh Pressed Olive Oil Club. Learn more at getfreshDrKahn.com . Dr. Kahn's new book can be found here: amazon.com/dp/B0HBGJ4J59
In this bonus episode, Dr. Kahn interviews functional medicine specialist Ivan Rusilko about the importance of advanced lab panels. Together, they explore the full spectrum of cardiac lab testing, with a special focus on inflammation, insulin resistance, and how these markers can uncover hidden cardiovascular risk. If you are a health care practitioner, set up an account at accessmedlab.com . Mention the Heart Doc VIP Podcast when creating your new practitioner account to receive 50% off CardioPro™ Advanced Diagnostic Panels , providing unparalleled insights into patient health.
This week, Dr. Kahn discusses the FDA approval of the first oral PCSK9 inhibitor, Lipfendra (enclicitide), taken as a 20 mg daily tablet. In a study of nearly 3,000 patients with elevated LDL cholesterol despite treatment with statins and, in many cases, ezetimibe, LDL-C dropped by more than 50% while Lipoprotein(a) levels fell by 28%, with an excellent safety profile. The medication is expected to retail for approximately $315 per month and will be available in pharmacies soon. A larger outcomes trial evaluating its impact on heart attack and stroke rates is currently underway. Other topics include oatmeal for diabetes, avocados for cholesterol, ketogenic diets and cancer, serotonin and heart valve disease, air pollution and cardiovascular events, and the relationship between sweetened beverages, fruit juice, and high blood pressure. Dr. Kahn also mentions the air filtration system he uses at home and in his office, available at: airdoctorpro.com Finally, thanks to this week's sponsor, the Fresh Pressed Olive Oil Club. Learn more at getfreshDrKahn.com .
This week, Dr. Joel Kahn explores important new research showing how elevated inflammation, measured by Interleukin-6 (IL-6), may dramatically increase cardiovascular risk in people with high Lipoprotein(a), or Lp(a). He explains why IL-6 is emerging as an important biomarker and reviews the other inflammation tests he routinely uses at the Kahn Center, including hs-CRP, MPO, Lp-PLA2, NT-proBNP, fibrinogen, ferritin, the sedimentation rate, and the white blood cell count. Dr. Kahn also discusses Lilly's newly approved oral weight loss medication, the ABCDEF framework for cardiovascular prevention, the growing evidence linking erectile dysfunction and sleep apnea to heart disease, new research on cannabis use and coronary artery plaque, and intriguing early findings on creatine's potential role in supporting the immune system and anti-tumor activity. Finally, thanks to this week's sponsor, the Fresh Pressed Olive Oil Club. Visit getfreshDrKahn.com to take advantage of their special introductory offer and experience the health benefits of fresh, polyphenol-rich olive oil.
Dr. Joel Kahn explores the latest science on supplements that may help slow or reverse atherosclerosis, building on a recent discussion from Simon Hill's The Proof podcast. He takes a closer look at the evidence behind vitamin K2, niacin, pycnogenol with centella asiatica, beta-cyclodextrin, and bergamot, explaining where the research is strongest and what it could mean for heart health. Additional topics include new research on nutrient deficiencies to watch for in vegan diets, the potential kidney risks of certain calcium channel blockers, the health benefits of onions, advanced plaque measurements from coronary CT angiography, the connection between periodontal disease and kidney disease, and how fasting-mimicking diets may improve gum health. Dr. Kahn also reviews encouraging early results from an emerging Lipoprotein(a)-lowering therapy that could reduce the need for lipoprotein apheresis. Dr. Kahn is leading a group PROLON fasting-mimicking diet beginning this Sunday, July 12, and continuing for five days. A PROLON kit is required and can be purchased at prolonlife.com/drkahn . The NextGen version is recommended. Finally, a giant thanks to this week's sponsor, Igennus. Learn more at igennus.com/drkahn .
This week, Dr. Kahn reviews important new research showing that the commonly prescribed antidepressant Prozac (fluoxetine) may disrupt cholesterol metabolism, injure the endothelium (the delicate lining of arteries), and potentially increase cardiovascular risk. He also examines growing evidence linking proton pump inhibitors (PPIs) and several common cancer therapies to endothelial damage, emphasizing that patients should always discuss the risks and benefits of these medications with their healthcare team rather than stopping treatment on their own. Other topics include new Harvard research showing that combining aerobic exercise, strength training, and less time spent watching television can reduce the risk of type 2 diabetes by up to 60%; promising data on niacin for glioblastoma brain cancer; predicting statin-related muscle injury; the protective effects of plant-based diets against heart disease, dementia, and several cancers; tea consumption and lower cardiovascular risk; vitamin K-rich leafy greens and lung health; whole grains and breast cancer prevention; and the latest research on red meat, inflammatory bowel disease, and hypertension. Thanks to igennus.com/drkahn for this week's podcast sponsorship featuring their vegan Super B Complex.
Can a simple gratitude practice improve your heart health? This week, Dr. Kahn explores the growing science linking gratitude to better well-being, improved sleep, lower inflammation, and even enhanced cardiac function. He shares his own gratitude practices and offers practical ways to incorporate them into daily life. Also covered in this episode: how adherence to Life's Essential 8 is associated with longevity, even among the ultra-elderly; the importance of identifying cholesterol hyperabsorbers; the connection between obesity and cancer risk; the relationship between sleep apnea and Lipoprotein(a); why strength training is especially important for women; and the link between hypothyroidism and elevated homocysteine levels. Thanks to IGENNUS for their support of this episode, featuring their vegan Pro-Collagen Powder. Learn more at igennus.com/drkahn .
In this special 500th episode of Heart Doc VIP, Dr. Joel Kahn reflects on the personal and professional journey that shaped his 36-year career in cardiology and preventive medicine. From his childhood in Detroit and medical training at the University of Michigan to founding the Kahn Center for Cardiac Longevity, Dr. Kahn shares the mentors, experiences, and lessons that influenced his approach to patient care. He also reviews new research on heart disease mortality in the United States, vitamin K2 and coronary artery calcium progression, plant-based diets for chronic kidney disease, factors influencing carotid intima-media thickness (CIMT), and emerging advances in calcium scoring technology. Thank you to Igennus for sponsoring this milestone episode. Visit Igennus.com/DrKahn and use code DRKAHN for savings on their vegan-certified supplements.
In Episode 499, Dr. Joel Kahn explores the growing importance of apolipoprotein B (ApoB) testing as a powerful tool for assessing cardiovascular risk. He reviews new research highlighting why ApoB may provide a more complete picture of atherosclerosis risk than traditional cholesterol measurements alone and explains how it relates to LDL-C and Lp(a). Dr. Kahn also discusses several noteworthy studies in preventive medicine and longevity, including research linking GLP-1 medications to lower cancer risk, the potential DNA-protective effects of melatonin, and new findings on stroke and clot prevention in patients with atrial fibrillation. Additional topics include the relationship between very low Lp(a) levels and diabetes risk, the benefits of organic produce for breast cancer prevention, Pilates training for blood pressure management, and the connection between processed meat consumption and gastrointestinal cancers. The episode concludes with a look at Endothelin-1 (ET-1), an important marker involved in vascular health and cardiovascular disease, along with a discussion of Vinia grape powder and its potential role in lowering ET-1 levels. Thanks to Igennus.com and their Triple Vitamin K Complex using the discount code DrKahn
Dr. Joel Kahn dives into a groundbreaking Phase 1 trial of Verve 102, a one-time intravenous gene-editing treatment that silences the PCSK9 gene to produce lasting LDL cholesterol reduction. Among 35 participants, the high-dose group saw LDL drop by 62% with mostly mild side effects — promising results, though Phase 2 and 3 trials and 15 years of follow-up still lie ahead. Also covered: updated colorectal cancer screening guidelines now starting at age 45, healthy lifestyle habits cutting mortality risk in cancer survivors by one-third, real-world weight regain data after stopping GLP-1 medications, why your B12 "normal" range may be too low, a blood test that may predict Alzheimer's years in advance, and a longevity preparedness tool from MIT AgeLab. Sponsored by Igennus — visit igennus.com/drkahn for 20% off.
In this episode of HeartDoc VIP, Dr. Joel Kahn breaks down the newly released — but not yet fully published — results from the highly anticipated Triumph-1 study on retatrutide, an investigational weight loss medication that's already generating major buzz in the cardiometabolic world. The reported weight loss results at 80 and 104 weeks are remarkable, with side effects appearing consistent with other medications in this class, including semaglutide and tirzepatide. Dr. Kahn discusses what's known so far, what questions still remain, and why the full peer-reviewed publication is so important before drawing final conclusions on risks and benefits. FDA approval may not be far away. Other topics in this packed episode include the troubling rise in fatal heart attacks among younger adults, a modified Mediterranean diet linked to lower diabetes risk, the connection between food preservatives and heart disease, atrial fibrillation in athletes, nitric oxide's role in brain health, fatty liver disease and cardiovascular risk, and how the American Heart Association's Life's Essential 8 score may predict diabetes risk in women. Thanks to Igennus for sponsoring this episode. Visit their site and use promo code DRKAHN to save on high-quality supplements.
This week, Dr. Kahn discusses Bryan Johnson's efforts to reverse his "biological age" and the 41 lessons he has shared along the way. These are valuable insights that Dr. Kahn largely endorses. Other topics include the sit-to-stand test; how PCOS can become PMOS; therapies for Peyronie's disease and PSA testing; plant-based diets and aging; plant-based diets during pregnancy; pregnancy complications; and the cardiac health of offspring. A big thanks to Igennus for supporting the podcast. Use discount code DrKahn to save on the BeKind line of plant-based nutritional products.
This week, Joel Kahn, MD, dives into fascinating new research on aged garlic extract and its potential role in healthy aging, muscle function, and cardiovascular wellness. He reviews a recent study showing how aged garlic extract improved muscle and aging markers in mice while also activating the NAMPT pathway in humans, which may help boost NAD+ production. Dr. Kahn also breaks down several newer studies highlighting the cardiovascular benefits of aged garlic extract, a supplement he's used at the Kahn Center for more than a decade. He discusses the specific Kyolic formula available here: Kyolic Aged Garlic Extract Additional topics include dietary nitrates from greens and nitric oxide production, the Mediterranean diet and longevity, high-intensity interval training and heart health, visual acuity and lifespan, plant-based diets and breast cancer outcomes, and the connection between poor sleep and survival rates. This episode is brought to you by VINIA and their line of heart-supporting products.
This week, Dr. Kahn discusses his long-standing interest in the amino acid glycine and its potential health benefits. Sleep is a key focus, highlighted by a new report on the widespread difficulty adults face in getting a full night's rest. Glycine may also offer favorable cardiovascular support. Additional topics include coffee and aging, methamphetamines and heart attacks, Lipoprotein(a) and cardiovascular risk, yoga and overall health, a tribute to Eugene Braunwald, MD, TMAO and atherosclerosis, and a new study on the benefits of adopting heart-healthy habits early in life. Thanks to the Fresh Pressed Olive Oil Club and the special discount offer at getfreshdrkahn.com
This week, Dr. Kahn reviews new data from the Global Burden of Disease study analyzing the relationship between diet and death from heart disease. In 2023, an estimated 5.9 million deaths worldwide were linked to poor dietary choices, led by excessive sodium intake and insufficient consumption of fruit and whole grains. It's a fascinating and important study with clear takeaways. Other topics include stents for angina, causes of sudden cardiac death, daytime napping and health outcomes, plastic-free diets, PCSK9 inhibitors vs. statins, calcium supplements, and the purity of fish oil samples. Thanks to the Fresh Pressed Olive Oil Club. Visit getfreshdrkahn.com for an incredible introductory offer.
This week, Dr. Kahn addresses a topic gaining attention in the media: whether taking the shingles vaccine (Shingrix in the USA) may reduce the risk of heart events and dementia. Multiple studies suggest this could be true, although no randomized trials have been performed to confirm it. Furthermore, most of these studies focus on a version of the vaccine that was discontinued in the U.S. in 2020 (Zostavax), making the assumption that Shingrix provides the same benefits somewhat speculative. This is a topic worth discussing with your primary care team. Other topics include controversies in nutrition, B vitamins and stroke risk, and the impact of medications for mild dementia. This episode is sponsored by the Fresh Pressed Olive Oil Club at getfreshdrkahn.com , featuring a limited $1 offer on high-quality olive oils.
This week, Dr. Kahn dives into heart disease in "masters athletes," highly active individuals over 35 who train and compete at a serious level. Despite their fitness, research shows they may face equal—or even higher—rates of cardiovascular issues like arrhythmias, coronary artery disease, and aortic dilation. A new consensus statement breaks down what to watch for and recommends advanced screening like EKGs, coronary calcium scans, and detailed blood work. Beyond that, Dr. Kahn shares insights from his own recent mitral valve surgery recovery and explores why common heart risk calculators often miss people who go on to have heart attacks. He highlights better testing options, including coronary calcium scoring, and discusses a study showing most heart attack patients would have been labeled "low risk" using standard tools. The episode also covers research on plant-based diets lowering dementia risk and reducing environmental impact, plus findings that avocados and mangos may improve vascular health. Sleep gets a spotlight too, with evidence that irregular sleep patterns can double heart attack risk, and that both too little and too much sleep may increase dementia risk. This episode is sponsored by the Fresh Pressed Olive Oil Club at getfreshdrkahn.com , featuring a limited $1 offer on high-quality olive oils.
This week, Dr. Kahn shares an update on his recovery following robotic mitral valve repair surgery at the Cleveland Clinic. Just 10–12 days post-op, he walks through his experience—from diagnosis and testing to surgery with Marc Gillinov, MD. He covers the procedure, time in the ICU, and early recovery milestones, along with what's next in his healing journey. Thanks to Igennus for sponsoring this episode—visit igennus.com and use code DrKahn.
This week, Dr. Kahn shares exciting updates from the American College of Cardiology meeting, highlighting several new trials focused on reducing heart events in patients with diabetes and those with established heart disease. The results are promising and could help prevent strokes, heart attacks, and even save lives. Additional topics include vegan diets and cancer risk, heart disease in police officers, the link between Alzheimer's disease and statins, concerns around erythritol sweeteners, Lp(a) levels in stent patients, niacin for fatty liver disease, and the role of beta blockers after heart attacks. This episode is brought to you by Igennus Healthcare Nutrition—formulators of high-quality, science-backed supplements designed for optimal absorption and effectiveness. Their products are rigorously tested and trusted by health professionals worldwide. Visit igennus.com and use code DrKahn to save on your order.
What if a quick, painless ultrasound could reveal your true vascular age? In this bonus episode of Heart Doc VIP, host Dr. Joel Kahn sits down with Joseph Ence to discuss CIMT (carotid intima-media thickness)—a simple, non-invasive test used in over 5,000 research studies over the past 20+ years to measure plaque and thickness in the carotid arteries. Safe and radiation-free, this ultrasound provides valuable insight into your cardiovascular health by estimating your "vascular age." They also explore how targeted interventions—like lifestyle changes, supplements, and medications—may help improve—and even reverse—vascular age.
