Published by Dr Karl Kruszelnicki
Dr Karl's a curious optimist. Join him as he explores the latest developments in science with leading researchers and communicators. And remember, it's never too late for a happy childhood. Series Producer: Isabelle Benton Technical Producer: Maya Cook Contact: shirtloadspodcast@gmail.com
Listen on Apple Podcasts33 min
Associate Professor Anai González Cordero joins us on Shirtloads to explore the remarkable world of stem cells and how they can develop into almost any cell in the human body! She explains how her team is using stem cell technology to better understand and develop potential treatments for inherited retinal diseases, including Stargardt disease and Usher syndrome. We also discuss her work at the Children's Medical Research Institute and the importance of supporting genetic research through Jeans for Genes Day (coming up on the 7th of August!) If you'd like to help fund life-changing genetic research, consider making a donation this Jeans for Genes Day www.cmrijeansforgenes.org.au/
27 min
What if evolution isn't just about the survival of the fittest? Rowan Hooper, senior editor at New Scientist, joins Shirtloads to discuss his new book Togetherness - a challenge to the idea that nature is defined purely by competition. From the fig and wasp's ancient partnership to the mycorrhizal fungal networks threading through forest soils, Hooper makes a compelling case that relationships and symbiosis are overlooked fundamental aspects of evolution.
32 min
This conversation was originally recorded and published in November, 2024. In light of Richard's passing, we wanted to share it again because his insights remain as inspiring and relevant as ever. We extend our deepest condolences to his family, friends and colleagues.
31 min
Dr. Ann Jones joins me to chat about her hilarious new What the Duck? series, Nature's Most Wanted , which dives into the wild world of criminal animals. We investigate some of nature's strangest case files… a duck caught speeding (twice), drug-addicted parrots, an underwear-nicking cat, drunk elephants, and heavyweight hamsters! A funny look at the surprising ways animals collide with the human rules we've created. What The Duck?! Nature's Most Wanted
25 min
Marine Ecologist Assoc. Professor Alex Campbell takes us into the wonderful, under-appreciated world of seaweed and makes the case that it might be one of our most powerful allies against climate change! We dive into seaweed's evolutionary history and the troubling decline now underway: as ocean temperatures rise, marine organisms are shifting toward the poles at a rate of over 60km per decade to escape the heat, with Tasmania's once-thriving giant kelp forests shrinking by a staggering 90% since the 1990s due to devastating changes to their habitat. But the story isn't all bad news. Seaweed also holds genuine promise as a climate solution - from carbon sequestration and biofuel production, to a renewable alternative to plastic, to livestock feed additives that can dramatically cut methane emissions. Alex makes a compelling case for why this humble marine organisms deserves a much bigger role in how we tackle climate change.
24 min
I'm joined by Dr Nick Fuller to dissect the long-term effectiveness of weight loss medications and why lasting results do actually require more than medication alone. Nick explains why evidence-based behavioural weight management programs remain the first-line approach to weight loss built on three key pillars: diet, exercise and sleep (did you even know that sleep plays a big role in regulating hunger hormones?!) Drawing on his team's research, Nick shares why many people regain weight after stopping medication and why behavioural change is essential for sustainable success (and keeping weight off for good!)
34 min
This episode I'm joined by Dr Peter Lee, Head of Research at Microsoft, to explore the ideas shaping the future of technology. Leading 14 research laboratories globally and overseeing a research and development program that receives more than 10% of Microsoft's overall budget, Dr Lee shares his journey to the top of one of the world's largest innovation engines. From AI tools transforming early cancer detection and predicting protein structures in hours (instead of years!), to discovering new battery materials and improving weather forecasting through deep learning, the conversation reveals how research is moving from possibility to real-world impact. We also explore Microsoft's investment in open-ended innovation, research not driven by immediate products, but by imagining entirely new experiences and technologies. Encrypted Spaces - Microsoft Research | Microsoft Research
28 min
In this episode, we speak with Dietmar Müller about the "Boring Billion", a seemingly quiet period in Earth's deep history that may have been crucial for the evolution of complex life. Drawing on his latest research, Müller explains how plate tectonics, passive continental margins, and volcanic outgassing shaped Earth's slow carbon cycle and gradually oxygenated the oceans during the mid-Proterozoic era. Müller also reflects on how young the science of plate tectonics really is, and discusses the open-source EarthByte tools his team at the University of Sydney has developed to model Earth's ancient geological past. www.earthbyte.org/
29 min
Astronomer and soon-to-be Dr. Kovi Rose joins us to discuss his newly published Nature Astronomy paper on one of the universe's newest mysteries: strange repeating flashes of radio waves and X-rays coming form deep within our galaxy! His team's discovery of ASKAP J174 has helped identify the source as a pair of stars orbiting each other, with a white dwarf pulling or accreting material from its companion. This discovery could help unlock the origins of mysterious signals flashing across the sky, unlocking even more secrets of the universe.
17 min
Professor Clare Collins returns to the pod to answer a common question: does coffee raise your blood pressure? We also discuss how genetics influence whether you're a fast or slow caffeine metaboliser, the beneficial phytonutrients found in coffee, why decaf still has health benefits, and when people with high blood pressure may need to be more cautious with their intake. nomoneynotime.com.au
30 min
Friend of the pod Professor Clare Collins returns to dive down into the sticky depths of the surprisingly powerful world of honey - far beyond being "just a sugary liquid". From the hallucinogenic "mad honey" of the Rhododendrons to the science behind medical-grade honey dressings that can heal wounds days faster than conventional treatments, Dr. Clare explains why this ancient food deserves a second look. We dive into honey's beneficial micronutrients, anti-inflammatory properties, and why the nutritional profile can vary dramatically depending on where bees source their pollen. Clare also busts the myth that honey is "bee vomit", revealing the fascinating biology behind how bees actually make honey and why these incredible insects deserve our respect! nomoneynotime.com.au
28 min
What is the universe actually made of? Particle physicist Theresa Fruth join us at Shirtloads to explore one of science's greatest unsolved mysteries - dark matter! Making up roughly 85% of the universe, yet appearing in none of our known particles, dark matter is invisible, elusive and almost certainly the reason the universe (and us!) exist at all. Theresa and her team are hunting for it anyway. Working 1.2 kilometres underground in a converted gold mine in regional Victoria, they're searching for WIMPs - weakly interacting massive particles - in one of the quietest, most interference-free environments on Earth. The lab is being built out now, and further experiments are on the horizon. We may be closer to one of the biggest discoveries in scientific history than we realise.
32 min
Professor Ollie Jay, a leading expert in heat and health, returns to Shirtloads to discuss the growing toll of climate change on human wellbeing and global economics. Insights drawn from the latest Lancet Countdown report show that over half a million people die from heat-related causes each year, and a million more from fossil fuel pollution - deaths that are largely preventable. Rising temperatures are quietly reshaping our daily lives, from reducing physical and cognitive productivity, to costing the global economy an estimated trillion dollars annually. But it's not all bleak - Professor Jay highlights that meaningful change is within reach. With the right political action and long-term interventions, we can protect both public health and economic stability - the solutions are already in our hands.
31 min
In this episode, we speak with Professor Emmanuel Stamatakis about Vigorous Intermittent Lifestyle Physical Activity (VILPA) - short bursts of high-intensity movement built into everyday life, like walking briskly or carrying groceries. With only a quarter of adults exercising regularly, his research highlights how incidental activity, when done with enough intensity, can offer meaningful health benefits. We discuss how VILPA is grounded in observational research and the idea of "exercise snacks" which describes quick, accessible moments of effort that add up. The focus is on helping people recognise and maximise these daily opportunities to improve fitness and support long-term health.
33 min
We're living through the great Space Boom and with great innovation comes a lot of whacky ideas... Astronomer and Associate Professor Michael Brown from Monash University joins me to discuss stupid things in space. The conversation dives into some of the more bizarre and ambitious ideas circulating the space industry, from firing villains and radioactive waste in to the sun to deploying giant orbital mirrors to light up Earth's dark side. Brown breaks down why many of these concepts are far less practical than they sound. With over 15,000 satellites circling earth, Brown also examines the promises and downsides of mega-constellations like Starlink, including how they operate and the challenges they pose for astronomers and the environment. It's a fascinating and critical peek in to the intersection of innovation, risk, and imagination in the new space age.
31 min
In this episode I sit down with Professor Conny Aerts, a pioneering mathematician and founding figure of astroseismology, who reveals how scientists are "listenting" to stars to understand what's happening deep inside them. From oscillating stars to solar sunquakes, she explains how sound waves can measure the sun's size, age and activity. Beyond the science, she shares her remarkable journey from a small rural town in Belgium where she had to attend an all-boys school, the only school near her family home. She was expected to become a seamstress but Conny's dreams were beyond this planet, leading her on a path toward becoming a highly acclaimed asteroseismologist.
30 min
We're scared to say the D word! But why is talking about death such a taboo? Dr. Hannah Gould, a cultural anthropologist at the University of Melbourne, joins me to discuss the topic in the wake of the release of her new book 'How To Die in the 21st Century'. The discussion dives in to the modern experience of dying, from the pressures of having a 'good death' to the reality of overly medicalised, 'prolonged dwindling'. Hannah unpacks how death isn't just biological but also cultural and legal, raising the question: When does death officially occur? The conversation is an invitation to rethink death - not as something to fear, but as something we can approach with openness, intention, and maybe even a sense of celebration https://www.hannahgould.com/
28 min
When a problem with the James Webb Space Telescope left its images frustratingly out of focus, the solution wasn't fixed in space... it was fixed from Earth. At the University of Sydney, PhD students Dr. Louis Desdoigts and Max Charles spent two years rewriting and refining code to recalibrate a critical instrument designed by Professor Peter Tuthill: the Aperture Masking Interferometer. Their breakthrough sharpened the telescope's infrared vision unlocking clearer views of distant worlds, including volcanic activity on Io, one of Jupiter's moons. In a fitting tribute, the pair even got matching tattoos of the hardware they helped fix! Not only did their work restore clarity to one of humanity's most powerful observatories, it also saved NASA the immense cost and impossibility of repairing the telescope in space.
26 min
This episode features Dr. Linzi Wilson-Wilde and Hannah Jarman discussing the realities of forensic science beyond shows like CSI . Through cases such as the Phantom of Heilbronn case and Lindy Chamberlain-Creighton, they explore how flawed evidence and forensic myths have contributed to wrongful convictions. They also examine common misconceptions around techniques like bite mark analysis, fire investigation, and glass evidence. The conversation emphasises the importance of approaching forensic science holistically, recognising it as just one piece of the broader investigative puzzle. www.epistemicsolutions.com.au/
30 min
Pharmacist and science communicator Kate Thomas shares how a viral debunking video launched her into the world of online health education. In this episode we explore the booming "wellness woo" economy and sift through the weeds on why misleading short-form content spreads so easily and the risks of unregulated wellness influencers. Kate breaks down the truth about supplements, the power of placebo, and why accessible, personalised health advice is so hard to find online. She also highlights the important role pharmacists play in helping consumers make informed choices. TikTok & Instagram: @PrescribeOrPass Linkedin: Kate Thomas
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